STRINGSTRING
ANS73281.1 ANS73281.1 ANS73282.1 ANS73282.1 ANS73748.1 ANS73748.1 ANS73749.1 ANS73749.1 sucC sucC sucD sucD sdhB sdhB sdhA sdhA ANS75609.1 ANS75609.1 ANS76936.1 ANS76936.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANS73281.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
ANS73282.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
ANS73748.1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
ANS73749.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
sucCFis family transcriptional regulator; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (309 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
ANS75609.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
ANS76936.1Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
Your Current Organism:
Paenibacillus yonginensis
NCBI taxonomy Id: 1462996
Other names: JCM 19885, KCTC 33428, P. yonginensis, Paenibacillus sp. DCY84, Paenibacillus yonginensis Sukweenadhi et al. 2016, strain DCY84
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.