STRINGSTRING
SAY55128.1 SAY55128.1 SAY55163.1 SAY55163.1 SAY55352.1 SAY55352.1 ypjD ypjD yfjD yfjD trmA trmA recJ recJ dsbC dsbC xerD xerD fldB fldB ygfX ygfX ygfY ygfY yqiA yqiA yqiB yqiB nudF nudF ygiB ygiB ygiC ygiC tusB tusB tusC tusC tusD tusD yheO yheO nudE nudE tusA tusA nudF_1 nudF_1 yjjX yjjX miaE miaE rdgC rdgC tusE tusE hflD hflD trmU trmU ymfB ymfB ymfC ymfC yeaC yeaC yciK yciK sohB sohB rnt rnt ychN ychN ycgN ycgN ycgM ycgM ycgL ycgL minC minC minD minD minE minE sbcB sbcB zipA zipA cysZ cysZ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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SAY55128.1Putative iron-regulated membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (452 aa)
SAY55163.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (153 aa)
SAY55352.1Hypothetical protein; No homology to any previously reported sequences. (71 aa)
ypjDConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (263 aa)
yfjDConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (428 aa)
trmAtRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (366 aa)
recJssDNA exonuclease, 5'--> 3'-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (577 aa)
dsbCProtein disulfide isomerase II; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (237 aa)
xerDSite-specific tyrosine recombinase; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically ex [...] (298 aa)
fldBFlavodoxin 2; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (173 aa)
ygfXHypothetical protein; No homology to any previously reported sequences. (136 aa)
ygfYConserved hypothetical protein; Homologs of previously reported genes of unknown function. (88 aa)
yqiAPutative esterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (191 aa)
yqiBPutative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (140 aa)
nudFADP-ribose pyrophosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (210 aa)
ygiBConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component; Belongs to the UPF0441 family. (223 aa)
ygiCPutative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (386 aa)
tusBMethylsulfur transfer protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (95 aa)
tusCMethylsulfur transfer protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (119 aa)
tusDMethylsulfur transfer protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE. (128 aa)
yheOPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (240 aa)
nudEADP-ribose diphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (186 aa)
tusASulfurtransferase; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. (81 aa)
nudF_1ADP-ribose pyrophosphatase; Belongs to the Nudix hydrolase family. (186 aa)
yjjXThiamin metabolism associated protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (171 aa)
miaEtRNA-(ms(2)io(6)A)-hydroxylase. (254 aa)
rdgCDNA-binding protein, non-specific; May be involved in recombination; Belongs to the RdgC family. (303 aa)
tusESubunit of enzyme for 2-thio modification of mnm5s2U of tRNA anticodon U; Part of a sulfur-relay system. (109 aa)
hflDPutative inner membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (213 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. (388 aa)
ymfBBifunctional thiamin pyrimidine pyrophosphate hydrolase and thiamin pyrophosphate hydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Nudix hydrolase family. NudJ subfamily. (152 aa)
ymfC23S rRNA pseudouridine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pseudouridine synthase RsuA family. (216 aa)
yeaCConserved hypothetical protein; Homologs of previously reported genes of unknown function. (92 aa)
yciKPutative oxoacyl-(acyl carrier protein) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (266 aa)
sohBPutative inner membrane peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (363 aa)
rntRibonuclease T (RNase T); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (215 aa)
ychNConserved hypothetical protein; Homologs of previously reported genes of unknown function. (117 aa)
ycgNConserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0260 family. (148 aa)
ycgMPutative isomerase/hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (219 aa)
ycgLConserved hypothetical protein; Homologs of previously reported genes of unknown function. (93 aa)
minCCell division inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (232 aa)
minDCell division inhibitor, a membrane ATPase,activates minC; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (270 aa)
minECell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (89 aa)
sbcBFunction of homologous gene experimentally demonstrated in an other organism; enzyme. (474 aa)
zipACell division protein involved in Z ring assembly; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (353 aa)
cysZPutative inner membrane protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (253 aa)
Your Current Organism:
Klebsiella quasipneumoniae
NCBI taxonomy Id: 1463164
Other names: CCTCC AB 206144 [[Klebsiella alba]], CIP 110770, DSM 28212, K. quasipneumoniae subsp. similipneumoniae, KCTC 12878 [[Klebsiella alba]], Klebsiella alba, Klebsiella alba Xu et al. 2015, Klebsiella quasipneumoniae subsp. similipneumoniae, Klebsiella quasipneumoniae subsp. similipneumoniae Brisse et al. 2014, Klebsiella sp. 07A044, Klebsiella sp. CW-D, LMG 24441 [[Klebsiella alba]], LMG:24441 [[Klebsiella alba]], strain 07A044, strain CW-D 3 [[Klebsiella alba]], strain SB30
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