STRINGSTRING
gap2 gap2 pgm pgm pgk pgk eno eno eda eda ABM69645.1 ABM69645.1 ABM69736.1 ABM69736.1 recO recO deoC deoC lrtA lrtA lipB lipB fadD fadD pdhC pdhC mqo mqo tal tal lplA lplA ABM69934.1 ABM69934.1 glk glk rpe rpe glpX glpX gnd gnd pgl pgl cbbA cbbA ABM70129.1 ABM70129.1 ABM70183.1 ABM70183.1 pdhB pdhB spt spt pykF pykF pgi pgi tpi tpi ABM70433.1 ABM70433.1 zwf zwf prsA prsA lipA lipA sdhA sdhA adhC adhC ABM70737.1 ABM70737.1 ABM70738.1 ABM70738.1 acoA acoA lpd lpd serA serA gpmI gpmI fumC fumC rpiA rpiA lipA-2 lipA-2 ppc ppc icd icd tktA tktA gcvP gcvP gcvH gcvH gcvT gcvT acnB acnB purU purU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gap2COG57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
pgmCOG33 Phosphoglucomutase [Carbohydrate transport and metabolism]. (545 aa)
pgkCOG126 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate kinase family. (402 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
edaCOG800 2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]. (208 aa)
ABM69645.1COG1012 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Belongs to the aldehyde dehydrogenase family. (463 aa)
ABM69736.1Possible Glycosyl transferase, group 1; COG438 Glycosyltransferase [Cell envelope biogenesis, outer membrane]. (385 aa)
recOPossible Recombination protein O (RecO); Involved in DNA repair and RecF pathway recombination. (261 aa)
deoCPutative deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (219 aa)
lrtALight repressed protein A; Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth. (194 aa)
lipBPutative lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (216 aa)
fadDPutative long-chain-fatty-acid--CoA ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism]. (647 aa)
pdhCDihydrolipoamide acetyltransferase; COG508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes [Energy production and conversion]. (455 aa)
mqoPutative malate/quinone oxidoreductase; COG579 Predicted dehydrogenase [General function prediction only]. (498 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (341 aa)
lplABiotin/lipoate A/B protein ligase family. (219 aa)
ABM69934.1Lipase family protein. (203 aa)
glkCOG837 Glucokinase [Carbohydrate transport and metabolism]; Belongs to the bacterial glucokinase family. (344 aa)
rpeCOG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Belongs to the ribulose-phosphate 3-epimerase family. (251 aa)
glpXFructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (333 aa)
gnd6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa)
pglPutative 6-phosphogluconolactonase (DevB, Pgl); Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (245 aa)
cbbAFructose-bisphosphate/sedoheptulose-1, 7-bisphosph ate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (357 aa)
ABM70129.1COG3588 Fructose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]. (355 aa)
ABM70183.1COG4240 Predicted kinase [General function prediction only]. (314 aa)
pdhBPyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
sptCOG75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]. (394 aa)
pykFCOG469 Pyruvate kinase [Carbohydrate transport and metabolism]; Belongs to the pyruvate kinase family. (596 aa)
pgiPhosphoglucose isomerase (PGI); COG166 Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Belongs to the GPI family. (527 aa)
tpiTriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa)
ABM70433.1COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (289 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
prsARibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (331 aa)
lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (299 aa)
sdhACOG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]. (584 aa)
adhCCOG1062 Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]. (355 aa)
ABM70737.1COG3959 Transketolase, N-terminal subunit [Carbohydrate transport and metabolism]. (288 aa)
ABM70738.1COG3958 Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]. (304 aa)
acoAPyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (357 aa)
lpdCOG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]. (479 aa)
serAPutative D-3-phosphoglycerate dehydrogenase (PGDH); COG111 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
gpmIPhosphoglycerate mutase, co-factor-independent (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (540 aa)
fumCFumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa)
lipA-2Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (297 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (989 aa)
icdCOG538 Isocitrate dehydrogenases [Energy production and conversion]. (474 aa)
tktATransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
gcvPCOG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain [Amino acid transport and metabolism]; Belongs to the GcvP family. (969 aa)
gcvHPutative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvTPutative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. (370 aa)
acnBAconitate hydratase B; COG1049 Aconitase B [Energy production and conversion]; Belongs to the aconitase/IPM isomerase family. (857 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa)
Your Current Organism:
Prochlorococcus marinus AS9601
NCBI taxonomy Id: 146891
Other names: P. marinus str. AS9601, Prochlorococcus marinus str. AS9601, Prochlorococcus sp. AS9601
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