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metF metF thy1 thy1 glyA glyA purH purH purN purN metH metH fmt fmt purT purT ABM70442.1 ABM70442.1 folD folD gcvT gcvT purU purU
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query proteins and first shell of interactors
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second shell of interactors
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metFCOG685 5,10-methylenetetrahydrofolate reductase [Amino acid transport and metabolism]; Belongs to the methylenetetrahydrofolate reductase family. (296 aa)
thy1Possible Thy1-like protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (210 aa)
glyASerine hydroxymethyltransferase (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
purHAICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain-containing protein; COG138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]. (517 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (218 aa)
metHPutative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1188 aa)
fmtPutative Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (328 aa)
purTGAR transformylase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa)
ABM70442.1COG212 5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (195 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (298 aa)
gcvTPutative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. (370 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (290 aa)
Your Current Organism:
Prochlorococcus marinus AS9601
NCBI taxonomy Id: 146891
Other names: P. marinus str. AS9601, Prochlorococcus marinus str. AS9601, Prochlorococcus sp. AS9601
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