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| | purL | Phosphoribosylformylglycinamidine synthetase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...] (779 aa) |
| | purF | Glutamine amidotransferase class-II:Phosphoribosyl transferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (486 aa) |
| | argH | Fumarate lyase:Delta crystallin; COG165 Argininosuccinate lyase [Amino acid transport and metabolism]. (459 aa) |
| | gap2 | COG57 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa) |
| | accB | Biotin / Lipoyl attachment:Acetyl-CoA biotin carboxyl carrier subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (168 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (152 aa) |
| | argJ | ArgJ family; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (412 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | pgm | COG33 Phosphoglucomutase [Carbohydrate transport and metabolism]. (545 aa) |
| | ABM69383.1 | Putative NADH dehydrogenase, transport associated; COG1252 NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]. (397 aa) |
| | ABM69400.1 | Inositol monophosphate family protein; COG483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]. (266 aa) |
| | ABM69410.1 | RibD/ribG C-terminal domain-containing protein; COG1985 Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]. (216 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (185 aa) |
| | hemD | Putative uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (265 aa) |
| | crtQ | Zeta-carotene desaturase; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'. (484 aa) |
| | ABM69429.1 | O-acetylserine (thiol)-lyase A; COG31 Cysteine synthase [Amino acid transport and metabolism]; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (472 aa) |
| | fabD | COG331 (acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]. (298 aa) |
| | ABM69443.1 | COG204 1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]. (206 aa) |
| | crtB | COG1562 Phytoene/squalene synthetase [Lipid metabolism]. (302 aa) |
| | pds | Phytoene desaturase; COG3349 Uncharacterized conserved protein [Function unknown]. (466 aa) |
| | cugP | Putative sugar-phosphate nucleotidyl transferase; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. (392 aa) |
| | gltA | COG372 Citrate synthase [Energy production and conversion]; Belongs to the citrate synthase family. (381 aa) |
| | trpB | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (414 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (163 aa) |
| | chlM | Mg-protoporphyrin IX methyltransferase; COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme metabolism]. (233 aa) |
| | ABM69479.1 | Predicted thioesterase; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily. (150 aa) |
| | menE | Probable O-succinylbenzoic acid--CoA ligase (OSB-CoA synthetase); COG318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism]. (400 aa) |
| | menC | Putative O-succinylbenzoate synthase; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (321 aa) |
| | menA | 1,4-dihydroxy-2-naphthoate (DHNA) octaprenyltransferase; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily. (305 aa) |
| | menF | COG1169 Isochorismate synthase [Coenzyme metabolism. (470 aa) |
| | dgkA | COG818 Diacylglycerol kinase [Cell envelope biogenesis, outer membrane]. (136 aa) |
| | ABM69492.1 | Aminotransferases class-I; COG79 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]. (369 aa) |
| | pgk | COG126 3-phosphoglycerate kinase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate kinase family. (402 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | hemB | COG113 Delta-aminolevulinic acid dehydratase [Coenzyme metabolism]; Belongs to the ALAD family. (333 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (365 aa) |
| | met3 | ATP-sulfurylase; COG2046 ATP sulfurylase (sulfate adenylyltransferase) [Inorganic ion transport and metabolism]. (391 aa) |
| | crtR | Beta-carotene hydroxylase; COG3239 Fatty acid desaturase [Lipid metabolism]. (277 aa) |
| | leuD | COG66 3-isopropylmalate dehydratase small subunit [Amino acid transport and metabolism]; Belongs to the LeuD family. (207 aa) |
| | leuC | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa) |
| | glyA | Serine hydroxymethyltransferase (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa) |
| | lytB | LytB; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (398 aa) |
| | purH | AICARFT/IMPCHase bienzyme:Methylglyoxal synthase-like domain-containing protein; COG138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]. (517 aa) |
| | hisB | COG131 Imidazoleglycerol-phosphate dehydratase [Amino acid transport and metabolism]. (201 aa) |
| | fabI | COG623 Enoyl-[acyl-carrier-protein]. (260 aa) |
| | chlD | Protoporphyrin IX Magnesium chelatase, ChlD subunit; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (727 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (413 aa) |
| | ABM69645.1 | COG1012 NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Belongs to the aldehyde dehydrogenase family. (463 aa) |
| | ABM69704.1 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]. (254 aa) |
| | aroQ | Dehydroquinase class II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (147 aa) |
| | proC | Delta 1-pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (270 aa) |
| | pdhC | Dihydrolipoamide acetyltransferase; COG508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes [Energy production and conversion]. (455 aa) |
| | ABM69745.1 | O-acetylserine (thiol)-lyase A; COG31 Cysteine synthase [Amino acid transport and metabolism]; Belongs to the cysteine synthase/cystathionine beta- synthase family. (328 aa) |
| | ABM69746.1 | COG626 Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]. (489 aa) |
| | metB | COG626 Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism]. (387 aa) |
| | mqo | Putative malate/quinone oxidoreductase; COG579 Predicted dehydrogenase [General function prediction only]. (498 aa) |
| | chlG | Chlorophyll synthase 33 kD subunit; COG382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases [Coenzyme metabolism]. (315 aa) |
| | hisF | Imidazole glycerol phosphate synthase subunit HisF (cyclase); IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (256 aa) |
| | ubiE | Ubiquinone/menaquinone biosynthesis methyltransferases; Methyltransferase required for the conversion of 2-phytyl- 1,4-beta-naphthoquinol to phylloquinol. (233 aa) |
| | ribE | COG307 Riboflavin synthase alpha chain [Coenzyme metabolism]. (217 aa) |
| | ctaA | COG1612 Uncharacterized protein required for cytochrome oxidase assembly [Posttranslational modification, protein turnover, chaperones]. (308 aa) |
| | cyoE | Putative protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (333 aa) |
| | ABM69797.1 | 3-oxoacyl-[acyl-carrier protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa) |
| | ispD | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (223 aa) |
| | ubiA | Probable 4-hydroxybenzoate-octaprenyltransferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate. Belongs to the UbiA prenyltransferase family. (302 aa) |
| | gltX | Glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (476 aa) |
| | hemL | COG1 Glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily. (433 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (316 aa) |
| | argB | Aspartokinase superfamily:Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (283 aa) |
| | gpmB | Possible alpha-ribazole-5'-P phosphatase; COG406 Fructose-2,6-bisphosphatase [Carbohydrate transport and metabolism]; Belongs to the phosphoglycerate mutase family. (442 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (341 aa) |
| | hemH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (391 aa) |
| | ilvB | COG28 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] [Amino acid transport and metabolism / Coenzyme metabolism]. (587 aa) |
| | accA | acetyl-CoA carboxylase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (335 aa) |
| | trpF | COG135 Phosphoribosylanthranilate isomerase [Amino acid transport and metabolism]; Belongs to the TrpF family. (218 aa) |
| | ABM69884.1 | Light dependent protochlorophyllide oxido-reductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (334 aa) |
| | chlL | Protochlorophyllide reductase iron-sulfur ATP-binding protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (295 aa) |
| | chlB | Light-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (523 aa) |
| | chlN | Light-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (418 aa) |
| | rbcL | Ribulose bisphosphate carboxylase, large chain; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (471 aa) |
| | rbcS | COG4451 Ribulose bisphosphate carboxylase small subunit [Energy production and conversion]. (113 aa) |
| | hisG | Possible ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (212 aa) |
| | trpA | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (261 aa) |
| | hisI | COG139 Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; In the N-terminal section; belongs to the PRA-CH family. (219 aa) |
| | hemE | Uroporphyrinogen decarboxylase (URO-D); Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (346 aa) |
| | glgB | 1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (754 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (436 aa) |
| | thrB | Homoserine kinase:GHMP kinases putative ATP-binding domain-containing protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (302 aa) |
| | glk | COG837 Glucokinase [Carbohydrate transport and metabolism]; Belongs to the bacterial glucokinase family. (344 aa) |
| | menD | Menaquinone biosynthesis protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). (587 aa) |
| | menB | Napthoate synthase; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (285 aa) |
| | glgA | Putative ADPglucose--glucosyltransferase (GlgA); Synthesizes alpha-1,4-glucan chains using ADP-glucose. (483 aa) |
| | aroA | EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (436 aa) |
| | sds | Polyprenyl synthetase; COG142 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Belongs to the FPP/GGPP synthase family. (323 aa) |
| | acs | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa) |
| | ABM69975.1 | Putative lycopene epsilon cyclase; COG644 Dehydrogenases (flavoproteins) [Energy production and conversion]. (422 aa) |
| | ABM69976.1 | Possible light-dependent protochlorophyllide oxido-reductase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]. (333 aa) |
| | met17 | COG2873 O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism]. (442 aa) |
| | metA | Putative homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (296 aa) |
| | aspC | Aminotransferases class-I; COG436 Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]. (392 aa) |
| | gcpE | GcpE protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (405 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (363 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (396 aa) |
| | pcyA | Ferredoxin-dependent biliverdin reductase; Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. Belongs to the HY2 family. (241 aa) |
| | chlP | Aromatic-ring hydroxylase (flavoprotein monooxygenase); COG644 Dehydrogenases (flavoproteins) [Energy production and conversion]. (446 aa) |
| | rpe | COG36 Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; Belongs to the ribulose-phosphate 3-epimerase family. (251 aa) |
| | glpX | Fructose-1,6-bisphosphatase/sedoheptulose-1, 7-bis phosphatase; Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6- phosphate and sedoheptulose 7-phosphate, respectively; Belongs to the FBPase class 2 family. (333 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (436 aa) |
| | glgC | COG448 ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (431 aa) |
| | gnd | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (472 aa) |
| | pgl | Putative 6-phosphogluconolactonase (DevB, Pgl); Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (245 aa) |
| | ilvD | COG129 Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism / Carbohydrate transport and metabolism]; Belongs to the IlvD/Edd family. (557 aa) |
| | purS | Phosphoribosylformylglycinamidine synthetase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to ass [...] (84 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (221 aa) |
| | cbbA | Fructose-bisphosphate/sedoheptulose-1, 7-bisphosph ate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (357 aa) |
| | ABM70129.1 | COG3588 Fructose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]. (355 aa) |
| | accD | acetyl-CoA carboxylase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (293 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa) |
| | proB | Putative glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (360 aa) |
| | hisA | COG106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase [Amino acid transport and metabolism]. (255 aa) |
| | ABM70183.1 | COG4240 Predicted kinase [General function prediction only]. (314 aa) |
| | trpD | Putative Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa) |
| | ispE | Putative 4-diphosphocytidyl-2C-methyl-D-erythritol kinase (CMK); Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (311 aa) |
| | pdhB | Pyruvate dehydrogenase E1 beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa) |
| | spt | COG75 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]. (394 aa) |
| | pykF | COG469 Pyruvate kinase [Carbohydrate transport and metabolism]; Belongs to the pyruvate kinase family. (596 aa) |
| | ilvA | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (513 aa) |
| | dxs | 1-deoxy-D-xylulose 5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (629 aa) |
| | hisZ | COG124 Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]. (383 aa) |
| | suhB | Possible myo-inositol-1(or 4)-monophosphatase; COG483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]. (282 aa) |
| | ribB | Possible GTP cyclohydrolase II / 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (574 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (351 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (218 aa) |
| | pgi | Phosphoglucose isomerase (PGI); COG166 Glucose-6-phosphate isomerase [Carbohydrate transport and metabolism]; Belongs to the GPI family. (527 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (286 aa) |
| | ABM70264.1 | COG1981 Predicted membrane protein [Function unknown]. (188 aa) |
| | ilvE | Putative Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (304 aa) |
| | metH | Putative methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1188 aa) |
| | pniL34 | Phytochrome-regulated protein; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (390 aa) |
| | ubiH | Possible 2-octaprenyl-6-methoxyphenol 4-monoxygenase; COG654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism. (384 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (282 aa) |
| | chlH | Protoporphyrin IX magnesium chelatase, subunit chlH; COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases [Coenzyme metabolism]. (1336 aa) |
| | tpi | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (241 aa) |
| | ansA | COG4448 L-asparaginase II [Amino acid transport and metabolism]. (321 aa) |
| | purT | GAR transformylase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa) |
| | thrA | Homoserine dehydrogenase:ACT domain-containing protein; COG460 Homoserine dehydrogenase [Amino acid transport and metabolism]. (433 aa) |
| | chlI | Protoporphyrin IX Magnesium chelatase, ChlI subunit; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (362 aa) |
| | hisH | Glutamine amidotransferase class-I; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa) |
| | guaB | COG516 IMP dehydrogenase/GMP reductase [Nucleotide transport and metabolism]. (387 aa) |
| | ABM70453.1 | Putative lycopene beta cyclase; COG644 Dehydrogenases (flavoproteins) [Energy production and conversion]. (403 aa) |
| | ABM70454.1 | COG1543 Uncharacterized conserved protein [Function unknown]; Belongs to the glycosyl hydrolase 57 family. (527 aa) |
| | leuA | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (546 aa) |
| | ispA | Polyprenyl synthetase; COG142 Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Belongs to the FPP/GGPP synthase family. (300 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa) |
| | prsA | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (331 aa) |
| | malQ | COG1640 4-alpha-glucanotransferase [Carbohydrate transport and metabolism]. (506 aa) |
| | cad | COG1982 Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]. (465 aa) |
| | cdsA | Phosphatidate cytidylyltransferase; COG575 CDP-diglyceride synthetase [Lipid metabolism]; Belongs to the CDS family. (285 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (457 aa) |
| | uppS | Undecaprenyl pyrophosphate synthetase (UPPS); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (267 aa) |
| | crtH | Putative carotenoid isomerase; COG1233 Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism]. (514 aa) |
| | sdhA | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [Energy production and conversion]. (584 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (404 aa) |
| | ilvN | COG440 Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]. (174 aa) |
| | aroH | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (127 aa) |
| | manC | COG836 Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Belongs to the mannose-6-phosphate isomerase type 2 family. (480 aa) |
| | rfbC | dTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (178 aa) |
| | ABM70700.1 | Hypothetical protein; COG107 Imidazoleglycerol-phosphate synthase [Amino acid transport and metabolism]; Belongs to the HisA/HisF family. (254 aa) |
| | ABM70701.1 | Hypothetical protein; COG118 Glutamine amidotransferase [Amino acid transport and metabolism]. (195 aa) |
| | ABM70723.1 | Putative sugar-phosphate nucleotidyl transferase; COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) [Cell envelope biogenesis, outer membrane / Translation, ribosomal structure an. (236 aa) |
| | adhC | COG1062 Zn-dependent alcohol dehydrogenases, class III [Energy production and conversion]. (355 aa) |
| | rfbB | COG1088 dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]. (332 aa) |
| | ABM70737.1 | COG3959 Transketolase, N-terminal subunit [Carbohydrate transport and metabolism]. (288 aa) |
| | ABM70738.1 | COG3958 Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]. (304 aa) |
| | argF | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (308 aa) |
| | ABM70747.1 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (364 aa) |
| | surE | Survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (269 aa) |
| | ribF | Putative riboflavin kinase/FAD synthase; COG196 FAD synthase [Coenzyme metabolism]; Belongs to the ribF family. (307 aa) |
| | trmD | Putative bifunctional enzyme: tRNA methyltransferase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP); Belongs to the RNA methyltransferase TrmD family. (408 aa) |
| | acoA | Pyruvate dehydrogenase E1 alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (357 aa) |
| | trpC | COG134 Indole-3-glycerol phosphate synthase [Amino acid transport and metabolism]; Belongs to the TrpC family. (295 aa) |
| | lpd | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]. (479 aa) |
| | argD | COG4992 Ornithine/acetylornithine aminotransferase [Amino acid transport and metabolism]; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (391 aa) |
| | panB | Putative Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (257 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (329 aa) |
| | glgX | Putative isoamylase; COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Belongs to the glycosyl hydrolase 13 family. (677 aa) |
| | plsY | Predicted membrane protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (197 aa) |
| | ABM70822.1 | Hypothetical protein. (105 aa) |
| | purD | Phosphoribosylglycinamide synthetase; COG151 Phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]; Belongs to the GARS family. (443 aa) |
| | serA | Putative D-3-phosphoglycerate dehydrogenase (PGDH); COG111 Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa) |
| | ABM70847.1 | Short-chain dehydrogenase/reductase (SDR) superfamily; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]. (309 aa) |
| | gpmI | Phosphoglycerate mutase, co-factor-independent (iPGM); Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (540 aa) |
| | purB | Fumarate lyase:Adenylosuccinate lyase; COG15 Adenylosuccinate lyase [Nucleotide transport and metabolism]; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa) |
| | fumC | Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (461 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | rpiA | Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (231 aa) |
| | dapL | Putative aminotransferase; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (408 aa) |
| | pheA | Chorismate mutase-Prephenate dehydratase; COG77 Prephenate dehydratase [Amino acid transport and metabolism]. (281 aa) |
| | ABM70991.1 | SAM (and some other nucleotide) binding motif; COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. (311 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (182 aa) |
| | tyrA | COG287 Prephenate dehydrogenase [Amino acid transport and metabolism]. (279 aa) |
| | ABM71067.1 | COG147 Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]. (506 aa) |
| | hemF | Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (342 aa) |
| | purM | Phosphoribosyl formylglycinamidine cyclo-ligase; COG150 Phosphoribosylaminoimidazole (AIR) synthetase [Nucleotide transport and metabolism]. (347 aa) |
| | cmk | Putative bifunctional enzyme; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily. (509 aa) |
| | pebB | Phycoerythrobilin:ferredoxin oxidoreductase; Catalyzes the two-electron reduction of the C2 and C3(1) diene system of 15,16-dihydrobiliverdin; Belongs to the HY2 family. (253 aa) |
| | pebA | Phycoerythrobilin:ferredoxin oxidoreductase; Catalyzes the two-electron reduction of biliverdin IX-alpha at the C15 methine bridge; Belongs to the HY2 family. (236 aa) |
| | ho1 | COG5398 Heme oxygenase [Inorganic ion transport and metabolism]. (236 aa) |
| | icd | COG538 Isocitrate dehydrogenases [Energy production and conversion]. (474 aa) |
| | glgP | Phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (854 aa) |
| | acpP | Acyl carrier protein (ACP); Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (79 aa) |
| | tktA | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa) |
| | ABM71120.1 | COG524 Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]. (332 aa) |
| | miaA | tRNA delta-2-isopentenylpyrophosphate (IPP) transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (299 aa) |
| | cysE | COG1045 Serine acetyltransferase [Amino acid transport and metabolism]. (244 aa) |
| | ribH | Putative 6,7-dimethyl-8-ribityllumazine synthase or riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (158 aa) |
| | lysC | COG527 Aspartokinases [Amino acid transport and metabolism]. (586 aa) |
| | dapA | Dihydrodipicolinate synthetase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa) |
| | asd | Aspartate Semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (343 aa) |
| | gcvP | COG1003 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain [Amino acid transport and metabolism]; Belongs to the GcvP family. (969 aa) |
| | gcvH | Putative Glycine cleavage H-protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | ubiC | 4-hydroxybenzoate synthetase (chorismate lyase). (167 aa) |
| | gcvT | Putative Glycine cleavage T-protein (aminomethyl transferase); The glycine cleavage system catalyzes the degradation of glycine. (370 aa) |
| | ABM71186.1 | Aminotransferases class-IV; COG115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]. (275 aa) |
| | cysG | Putative uroporphyrin-III C-methyltransferase; COG7 Uroporphyrinogen-III methylase [Coenzyme metabolism]; Belongs to the precorrin methyltransferase family. (267 aa) |
| | aroG | DAHP synthetase class I; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (355 aa) |
| | acnB | Aconitate hydratase B; COG1049 Aconitase B [Energy production and conversion]; Belongs to the aconitase/IPM isomerase family. (857 aa) |
| | aroE | Shikimate / quinate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (286 aa) |
| | argG | COG137 Argininosuccinate synthase [Amino acid transport and metabolism]; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (404 aa) |
| | ABM71203.1 | Sucrose phosphate synthase; COG438 Glycosyltransferase [Cell envelope biogenesis, outer membrane]. (469 aa) |
| | thrC | Threonine synthase: Pyridoxal-5'-phosphate-dependent enzymes, beta family; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (367 aa) |
