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ureA ureA ureB ureB ureC ureC ureE ureE ureF ureF ureG ureG ureD ureD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ureAUrease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. (100 aa)
ureBUrease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family. (122 aa)
ureCUrease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (167 aa)
ureFUrease accessory protein UreF; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (220 aa)
ureGUrease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. (209 aa)
ureDUrease accessory protein UreD; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (268 aa)
Your Current Organism:
Sporosarcina psychrophila
NCBI taxonomy Id: 1476
Other names: ATCC 23304, BCRC 11738, Bacillus psychrophilus, CCM 2117, CCRC 11738, CCRC:11738, CCUG 28886, CIP 103267, DSM 3, IAM 12468, IFO 15381, JCM 9075, LMG 6929, LMG:6929, NBRC 15381, NRRL B-3397, S. psychrophila
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