STRINGSTRING
thrS thrS EO98_18050 EO98_18050 ef1B ef1B rpl21e rpl21e EO98_18400 EO98_18400 lig lig EO98_18690 EO98_18690 EO98_19060 EO98_19060 EO98_19260 EO98_19260 EO98_00040 EO98_00040 EO98_00150 EO98_00150 priS priS rpl44e rpl44e rps27e rps27e EO98_00195 EO98_00195 tfb tfb rps2 rps2 rpoK rpoK rpoN rpoN rps9 rps9 rpl13 rpl13 rpl18e rpl18e gltX gltX EO98_00575 EO98_00575 lysS lysS EO98_00930 EO98_00930 pth pth EO98_01325 EO98_01325 EO98_01800 EO98_01800 EO98_01850 EO98_01850 EO98_01870 EO98_01870 sepS sepS EO98_02015 EO98_02015 EO98_02020 EO98_02020 EO98_02025 EO98_02025 EO98_02030 EO98_02030 argS argS prf1 prf1 polB polB rpl7ae rpl7ae rps28e rps28e rpl24e rpl24e infB infB rps6e rps6e EO98_02735 EO98_02735 dbh dbh serS serS rps3ae rps3ae rpl37ae rpl37ae rpl15e rpl15e EO98_03470 EO98_03470 alaS alaS rpl10e rpl10e eif2b eif2b trpS trpS pheS pheS pylS pylS EO98_04105 EO98_04105 EO98_04110 EO98_04110 priL priL valS valS EO98_04535 EO98_04535 EO98_04575 EO98_04575 EO98_04580 EO98_04580 EO98_04595 EO98_04595 EO98_04620 EO98_04620 EO98_05325 EO98_05325 tyrS tyrS EO98_05725 EO98_05725 eif1a eif1a polC polC gatB gatB gatA gatA gatC gatC rps17e rps17e EO98_06350 EO98_06350 uppS uppS EO98_06535 EO98_06535 EO98_06540 EO98_06540 EO98_06545 EO98_06545 rps24e rps24e EO98_06690 EO98_06690 eif2g eif2g EO98_06735 EO98_06735 leuS leuS glmS glmS ileS ileS EO98_07405 EO98_07405 rpoD rpoD rps11 rps11 rps4 rps4 rps13 rps13 EO98_07795 EO98_07795 cpsB cpsB EO98_07965 EO98_07965 EO98_08020 EO98_08020 dnaG dnaG EO98_08195 EO98_08195 rpoH rpoH EO98_08825 EO98_08825 EO98_08830 EO98_08830 EO98_08835 EO98_08835 rpoA2 rpoA2 rpl30e rpl30e nusA nusA rps12 rps12 rps7 rps7 fusA fusA tuf tuf rps10p rps10p rpoL rpoL EO98_09195 EO98_09195 EO98_09220 EO98_09220 cysS cysS lysS-2 lysS-2 EO98_09410 EO98_09410 EO98_09505 EO98_09505 serS-2 serS-2 metG metG dbh-2 dbh-2 eif5a eif5a rpl40e rpl40e proS proS EO98_10380 EO98_10380 tfe tfe rpl3 rpl3 rpl4lp rpl4lp rpl23 rpl23 rpl2p rpl2p rps19p rps19p rpl22 rpl22 rps3 rps3 rpl29 rpl29 rps17 rps17 rpl14 rpl14 rpl24p rpl24p rps4e rps4e rpl5 rpl5 rps14 rps14 rps8 rps8 rpl6 rpl6 rpl32e rpl32e rpl19e rpl19e rpl18 rpl18 rps5 rps5 rpl30p rpl30p rpl15 rpl15 gatE gatE rps19e rps19e rpl31e rpl31e eif6 eif6 rpl18a rpl18a rps8e rps8e hisS hisS rps15 rps15 EO98_11530 EO98_11530 EO98_11700 EO98_11700 EO98_11820 EO98_11820 EO98_11825 EO98_11825 EO98_11860 EO98_11860 EO98_12995 EO98_12995 EO98_13005 EO98_13005 EO98_13015 EO98_13015 EO98_13055 EO98_13055 EO98_13170 EO98_13170 EO98_13310 EO98_13310 EO98_13315 EO98_13315 EO98_13340 EO98_13340 EO98_13345 EO98_13345 EO98_13480 EO98_13480 EO98_13505 EO98_13505 EO98_13520 EO98_13520 EO98_13540 EO98_13540 EO98_14005 EO98_14005 tbp tbp rpl12p rpl12p rplP0 rplP0 rpl1 rpl1 rpl11 rpl11 nusG nusG EO98_14490 EO98_14490 EO98_14495 EO98_14495 aspC aspC EO98_14935 EO98_14935 pheT pheT EO98_15675 EO98_15675 EO98_16535 EO98_16535 EO98_16905 EO98_16905 eif1a-2 eif1a-2 eif1a-3 eif1a-3 gatD gatD rrmJ rrmJ EO98_17305 EO98_17305 eif1a-4 eif1a-4
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
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thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (635 aa)
EO98_18050Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (555 aa)
ef1BElongation factor 1-beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (89 aa)
rpl21e50S ribosomal protein L21; Mediates an interaction between 5S and domains II and V of 23S; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL21 family. (97 aa)
EO98_18400DNA-directed RNA polymerase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
ligDNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (568 aa)
EO98_18690Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1928 aa)
EO98_19060Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
EO98_19260O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (454 aa)
EO98_00040Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
EO98_00150Fibronectin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (790 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (414 aa)
rpl44e50S ribosomal protein L44; Binds to the 23S rRNA. (92 aa)
rps27e30S ribosomal protein S27; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
EO98_00195Translation initiation factor IF-2 subunit alpha; eIF-2A; functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa)
rps230S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (245 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa)
rpoNDNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa)
rps930S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (134 aa)
rpl1350S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (140 aa)
rpl18eHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL18 family. (126 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa)
EO98_00575Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
lysSlysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (537 aa)
EO98_00930Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
pthpeptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. (115 aa)
EO98_01325Aminotransferase DegT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (369 aa)
EO98_01800alanyl-tRNA editing protein AlaX; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
EO98_01850glycyl-tRNA synthetease; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
EO98_01870Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
sepSO-phosphoseryl-tRNA ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa)
EO98_02015Deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
EO98_02020Deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
EO98_02025Deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
EO98_02030Deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (569 aa)
prf1Peptide chain release factor 1; Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. (415 aa)
polBDNA polymerase II; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (679 aa)
rpl7ae50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
rps28e30S ribosomal protein S28; The function of S28E in the ribosome is unknown but the structure shows a variants OB-fold that is found in nucleic acid-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (73 aa)
rpl24e50S ribosomal protein L24; Binds to the 23S rRNA. (62 aa)
infBTranslation initiation factor IF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (591 aa)
rps6e30S ribosomal protein S6; The function of this ribosomal subunit is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology. (134 aa)
EO98_027353'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
dbhDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (361 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (502 aa)
rps3aeThe function for this protein is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS1 family. (204 aa)
rpl37ae50S ribosomal protein L37; Binds to the 23S rRNA. (94 aa)
rpl15eHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL15 family. (196 aa)
EO98_03470Glycosyl transferase family A; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (925 aa)
rpl10e50S ribosomal protein L10e; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL16 family. (173 aa)
eif2bTranslation initiation factor IF-2 subunit beta; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family. (202 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (437 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (492 aa)
pylSpyrolysyl-tRNA ligase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (502 aa)
EO98_04105DNA mismatch repair protein MutT; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
EO98_04110DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (104 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (371 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (869 aa)
EO98_04535Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (398 aa)
EO98_04575Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
EO98_04580Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
EO98_04595Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
EO98_04620UDP-N-acetylglucosamine-1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
EO98_05325Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa)
EO98_05725DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (935 aa)
eif1aTranslation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (111 aa)
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1150 aa)
gatBglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (495 aa)
gatAglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (475 aa)
gatCglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (93 aa)
rps17eHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS17 family. (64 aa)
EO98_06350Oligosaccharyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (842 aa)
uppSUDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids. (298 aa)
EO98_06535Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (377 aa)
EO98_06540Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
EO98_06545Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
rps24e30S ribosomal protein S24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS24 family. (101 aa)
EO98_06690DNA-directed RNA polymerase subunit E; Participates in both the initiation and recycling phases of transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
eif2gTranslation initiation factor IF-2 subunit gamma; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. (408 aa)
EO98_06735Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
leuSleucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...] (966 aa)
glmSGlutamine amidotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (618 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1059 aa)
EO98_07405Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (266 aa)
rps1130S ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (126 aa)
rps430S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (221 aa)
rps1330S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (162 aa)
EO98_07795dolichol-P-glucose synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
cpsBMannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family. (455 aa)
EO98_07965Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
EO98_08020GDP-mannose dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (518 aa)
EO98_08195Elongation factor Tu; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa)
EO98_08825DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
EO98_08830DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa)
EO98_08835DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa)
rpoA2DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (399 aa)
rpl30e50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL30 family. (96 aa)
nusATranscription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (141 aa)
rps1230S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (142 aa)
rps730S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (186 aa)
fusAElongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (730 aa)
tufElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (422 aa)
rps10p30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (92 aa)
EO98_09195Sep-tRNA:Cys-tRNA ligase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa)
EO98_09220Phenylacetic acid degradation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
lysS-2lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (511 aa)
EO98_09410Translation initiation factor Sui1; In yeast this protein is involved in start site selection during the initiation of translation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUI1 family. (102 aa)
EO98_09505Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (721 aa)
serS-2seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (711 aa)
dbh-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (365 aa)
eif5aTranslation initiation factor 5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family. (128 aa)
rpl40e50S ribosomal protein L40; Contains a zinc-finger motif; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL40 family. (49 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa)
EO98_10380RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
tfeTranscription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (164 aa)
rpl350S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (337 aa)
rpl4lp50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (253 aa)
rpl2350S ribosomal protein L23; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (82 aa)
rpl2p50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
rps19p30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (136 aa)
rpl2250S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (151 aa)
rps330S ribosomal protein S3; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (308 aa)
rpl2950S ribosomal protein L29; One of the stabilizing components for the large ribosomal subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
rps1730S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (109 aa)
rpl1450S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (132 aa)
rpl24p50S ribosomal protein L24; Located at the polypeptide exit tunnel on the outside of the subunit. (116 aa)
rps4eHypothetical protein; The function of this ribosomal subunit is unknown; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
rpl550S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (169 aa)
rps1430S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles. (50 aa)
rps830S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa)
rpl650S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (172 aa)
rpl32e50S ribosomal protein L32; Contacts helix 25 of domain II of the 23S rRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eL32 family. (146 aa)
rpl19e50S ribosomal protein L19; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (151 aa)
rpl1850S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (174 aa)
rps530S ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy. (209 aa)
rpl30p50S ribosomal protein L30; L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
rpl1550S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (140 aa)
gatEglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (633 aa)
rps19e30S ribosomal protein S19; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (149 aa)
rpl31e50S ribosomal protein L31; One of the proteins encircling the polypeptide exit tunnel in the ribozyme; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribosomal protein L31e family. (89 aa)
eif6Translation initiation factor IF-6; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (219 aa)
rpl18a50S ribosomal protein LX; Derived by automated computational analysis using gene prediction method: Protein Homology. (58 aa)
rps8eHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
hisShistidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (413 aa)
rps1530S ribosomal protein S15; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
EO98_11530Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
EO98_11700Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
EO98_11820Hexosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
EO98_11825Mannosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
EO98_11860Peptide transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (829 aa)
EO98_12995Translocase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
EO98_13005NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (475 aa)
EO98_13015Aminotransferase DegT; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (360 aa)
EO98_13055Dolichyl-phosphate mannose synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
EO98_13170Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
EO98_13310Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
EO98_13315Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
EO98_13340Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
EO98_13345Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
EO98_13480UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
EO98_13505Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
EO98_13520Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
EO98_13540Dolichyl-phosphate beta-D-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
EO98_14005GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
tbpTranscription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa)
rpl12p50S ribosomal protein L12; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (102 aa)
rplP0Acidic ribosomal protein P0; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (344 aa)
rpl150S ribosomal protein L1; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa)
rpl1150S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (161 aa)
nusGTranscription antiterminator NusG; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. (152 aa)
EO98_14490Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
EO98_14495Oligosaccharyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (847 aa)
aspCaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (444 aa)
EO98_14935ACT domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family. (92 aa)
pheTphenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
EO98_15675ATPase; Originally found to be an inhibitor of the antiviral RNase-L in human cells; contains ABC-type nucleotide binding domains; putatively functions in RNA maturation; Derived by automated computational analysis using gene prediction method: Protein Homology. (588 aa)
EO98_16535alpha-L-glutamate ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
EO98_16905AsnC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
eif1a-2Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (110 aa)
eif1a-3Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (107 aa)
gatDglutamyl-tRNA amidotransferase; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate. (424 aa)
rrmJ23S rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (278 aa)
EO98_17305Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
eif1a-4Translation initiation factor 1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (110 aa)
Your Current Organism:
Methanosarcina sp. 2HT1A6
NCBI taxonomy Id: 1483599
Other names: M. sp. 2.H.T.1A.6, Methanosarcina sp. 2.H.T.1A.6
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