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EO98_04910 EO98_04910 EO98_19260 EO98_19260 EO98_19050 EO98_19050 EO98_18690 EO98_18690 EO98_18590 EO98_18590 rsmA rsmA EO98_18400 EO98_18400 pus10 pus10 trmY trmY trm1 trm1 thiI thiI EO98_17770 EO98_17770 EO98_17660 EO98_17660 thrS thrS EO98_17280 EO98_17280 EO98_16900 EO98_16900 cas2 cas2 EO98_16380 EO98_16380 endA endA EO98_16275 EO98_16275 cca cca tiaS tiaS EO98_15635 EO98_15635 rnhB rnhB pheT pheT EO98_15300 EO98_15300 EO98_15155 EO98_15155 EO98_15070 EO98_15070 EO98_14955 EO98_14955 EO98_14935 EO98_14935 aspC aspC dtdA dtdA tbp tbp tgtA tgtA EO98_13415 EO98_13415 EO98_12580 EO98_12580 flpA flpA rnp4 rnp4 rtcB rtcB EO98_12195 EO98_12195 EO98_11915 EO98_11915 truA truA hisS hisS EO98_11275 EO98_11275 EO98_11240 EO98_11240 EO98_10920 EO98_10920 rnp1 rnp1 tfe tfe EO98_10445 EO98_10445 proS proS EO98_10260 EO98_10260 EO98_10250 EO98_10250 fen fen metG metG serS-2 serS-2 lysS-2 lysS-2 cysS cysS EO98_09235 EO98_09235 EO98_09195 EO98_09195 rpoL rpoL csl4 csl4 EO98_09080 EO98_09080 nusA nusA rpoA2 rpoA2 EO98_08835 EO98_08835 EO98_08830 EO98_08830 EO98_08825 EO98_08825 rpoH rpoH kptA kptA rtcA rtcA dnaG dnaG EO98_08095 EO98_08095 EO98_07825 EO98_07825 truB truB rpoD rpoD EO98_07610 EO98_07610 EO98_07590 EO98_07590 taw2 taw2 ileS ileS rnz rnz leuS leuS EO98_06695 EO98_06695 EO98_06690 EO98_06690 EO98_06650 EO98_06650 EO98_06190 EO98_06190 EO98_06010 EO98_06010 EO98_05765 EO98_05765 EO98_05480 EO98_05480 EO98_05435 EO98_05435 tyrS tyrS EO98_05395 EO98_05395 EO98_04825 EO98_04825 valS valS priL priL EO98_04110 EO98_04110 EO98_04055 EO98_04055 pylS pylS pheS pheS trpS trpS EO98_03695 EO98_03695 alaS alaS EO98_03395 EO98_03395 rnp3 rnp3 rrp4 rrp4 rrp41 rrp41 rrp42 rrp42 EO98_03270 EO98_03270 EO98_03260 EO98_03260 serS serS rps28e rps28e rpl7ae rpl7ae vapC vapC EO98_02105 EO98_02105 taw1 taw1 argS argS sepS sepS EO98_01880 EO98_01880 EO98_01870 EO98_01870 EO98_01850 EO98_01850 EO98_01800 EO98_01800 EO98_01545 EO98_01545 EO98_01490 EO98_01490 truD truD lysS lysS gltX gltX rps9 rps9 rpoN rpoN rpoK rpoK rnj rnj EO98_00360 EO98_00360 tfb tfb EO98_00345 EO98_00345 priS priS pelA pelA EO98_00040 EO98_00040
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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EO98_04910Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (344 aa)
EO98_19260O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (454 aa)
EO98_19050Arylsulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
EO98_18690Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1928 aa)
EO98_18590Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
rsmA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (269 aa)
EO98_18400DNA-directed RNA polymerase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
pus10Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (431 aa)
trmYtRNA (pseudouridine-N1)-methyltransferase; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (211 aa)
trm1tRNA (guanine-N2)-dimethyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (388 aa)
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (412 aa)
EO98_17770Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
EO98_17660Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (635 aa)
EO98_17280Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
EO98_16900LSM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa)
EO98_16380Exoribonuclease II; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
endARibonuclease BN; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (350 aa)
EO98_16275Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
ccaCCA-adding protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa)
tiaStRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (428 aa)
EO98_15635Small nuclear ribonucleoprotein; Enables 3` processing of polyadenylated mRNAs and tRNA precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the snRNP Sm proteins family. (72 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (247 aa)
pheTphenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
EO98_15300Hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (173 aa)
EO98_15155Methionine-10+; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
EO98_15070Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
EO98_14955tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (177 aa)
EO98_14935ACT domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family. (92 aa)
aspCaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (444 aa)
dtdAD-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (298 aa)
tbpTranscription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa)
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (490 aa)
EO98_13415RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
EO98_12580Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
flpAFibrillin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa)
rnp4Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (107 aa)
rtcBtRNA-splicing ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (500 aa)
EO98_12195Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (146 aa)
EO98_11915RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
truAPseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (269 aa)
hisShistidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (413 aa)
EO98_11275DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
EO98_11240Queuine tRNA-ribosyltransferase containing PUA domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
EO98_10920ATP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
rnp1Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (110 aa)
tfeTranscription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (164 aa)
EO98_10445Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa)
EO98_10260Sulfur reduction protein DsrE; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
EO98_10250Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
fenFlap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (338 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (711 aa)
serS-2seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa)
lysS-2lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (511 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
EO98_09235Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
EO98_09195Sep-tRNA:Cys-tRNA ligase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (92 aa)
csl4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (328 aa)
EO98_09080Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
nusATranscription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (141 aa)
rpoA2DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (399 aa)
EO98_08835DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa)
EO98_08830DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa)
EO98_08825DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa)
kptARNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (207 aa)
rtcARibosomal subunit interface protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (355 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (518 aa)
EO98_08095tRNA-ribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (625 aa)
EO98_07825Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
truBH/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (266 aa)
EO98_07610Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
EO98_075902-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
taw2Methyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (343 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1059 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (305 aa)
leuSleucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...] (966 aa)
EO98_06695DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
EO98_06690DNA-directed RNA polymerase subunit E; Participates in both the initiation and recycling phases of transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
EO98_06650Serine/threonine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (547 aa)
EO98_06190Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
EO98_06010tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (363 aa)
EO98_05765Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
EO98_05480Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
EO98_05435Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa)
EO98_05395SirA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
EO98_04825Hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (247 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (869 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (371 aa)
EO98_04110DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (104 aa)
EO98_04055Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
pylSpyrolysyl-tRNA ligase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (502 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (492 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (437 aa)
EO98_03695RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (925 aa)
EO98_03395Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (61 aa)
rnp3Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (239 aa)
rrp4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (260 aa)
rrp41Exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (484 aa)
rrp42RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (266 aa)
EO98_03270Ribosomal biosynthesis protein; Probably involved in the biogenesis of the ribosome. (157 aa)
EO98_03260Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (502 aa)
rps28e30S ribosomal protein S28; The function of S28E in the ribosome is unknown but the structure shows a variants OB-fold that is found in nucleic acid-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (73 aa)
rpl7ae50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
vapCTwitching motility protein PilT; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (130 aa)
EO98_02105Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (345 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (569 aa)
sepSO-phosphoseryl-tRNA ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa)
EO98_01880Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
EO98_01870Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
EO98_01850glycyl-tRNA synthetease; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
EO98_01800alanyl-tRNA editing protein AlaX; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
EO98_01545Methanogenesis marker protein 11; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
EO98_01490ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
truDPseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (438 aa)
lysSlysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (537 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa)
rps930S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (134 aa)
rpoNDNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa)
EO98_00360H/ACA RNA-protein complex protein Gar1; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa)
EO98_00345tRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (414 aa)
pelAmRNA surveillance protein Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (350 aa)
EO98_00040Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
Your Current Organism:
Methanosarcina sp. 2HT1A6
NCBI taxonomy Id: 1483599
Other names: M. sp. 2.H.T.1A.6, Methanosarcina sp. 2.H.T.1A.6
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