STRINGSTRING
cas2 cas2 EO98_16415 EO98_16415 EO98_16525 EO98_16525 EO98_16900 EO98_16900 EO98_17280 EO98_17280 thrS thrS EO98_17660 EO98_17660 EO98_17770 EO98_17770 rfcL rfcL EO98_18020 EO98_18020 EO98_18025 EO98_18025 EO98_18030 EO98_18030 EO98_18050 EO98_18050 dnaJ dnaJ thiI thiI trm1 trm1 trmY trmY pus10 pus10 EO98_18400 EO98_18400 rsmA rsmA lig lig EO98_18565 EO98_18565 EO98_18590 EO98_18590 EO98_18690 EO98_18690 cas1-2 cas1-2 cas1-3 cas1-3 EO98_19050 EO98_19050 EO98_19260 EO98_19260 EO98_19280 EO98_19280 EO98_19290 EO98_19290 EO98_19460 EO98_19460 EO98_01545 EO98_01545 EO98_01490 EO98_01490 truD truD lysS lysS EO98_00595 EO98_00595 gltX gltX EO98_00455 EO98_00455 rps9 rps9 rpoN rpoN rpoK rpoK rnj rnj EO98_00360 EO98_00360 tfb tfb EO98_00345 EO98_00345 EO98_00285 EO98_00285 EO98_00205 EO98_00205 priS priS pelA pelA rfcS rfcS EO98_00040 EO98_00040 EO98_01730 EO98_01730 EO98_01775 EO98_01775 EO98_01800 EO98_01800 EO98_01850 EO98_01850 EO98_01855 EO98_01855 EO98_01870 EO98_01870 EO98_01880 EO98_01880 sepS sepS EO98_01895 EO98_01895 cdc6 cdc6 mutS2 mutS2 EO98_01955 EO98_01955 EO98_01965 EO98_01965 argS argS taw1 taw1 polB polB EO98_02105 EO98_02105 vapC vapC rpl7ae rpl7ae rps28e rps28e gyrA gyrA gyrB gyrB top6A top6A top6B top6B EO98_02735 EO98_02735 dbh dbh EO98_02985 EO98_02985 serS serS EO98_03260 EO98_03260 EO98_03270 EO98_03270 rrp42 rrp42 rrp41 rrp41 rrp4 rrp4 rnp3 rnp3 EO98_03345 EO98_03345 EO98_03360 EO98_03360 EO98_03375 EO98_03375 EO98_03395 EO98_03395 alaS alaS EO98_03695 EO98_03695 trpS trpS pheS pheS pylS pylS EO98_03965 EO98_03965 EO98_04055 EO98_04055 EO98_04110 EO98_04110 pcn pcn priL priL EO98_04305 EO98_04305 EO98_04310 EO98_04310 valS valS EO98_04695 EO98_04695 EO98_04705 EO98_04705 EO98_04760 EO98_04760 EO98_04785 EO98_04785 EO98_04825 EO98_04825 EO98_04845 EO98_04845 EO98_04910 EO98_04910 EO98_05310 EO98_05310 EO98_05395 EO98_05395 tyrS tyrS EO98_05435 EO98_05435 EO98_05465 EO98_05465 EO98_05480 EO98_05480 EO98_05725 EO98_05725 EO98_05765 EO98_05765 nth nth EO98_06010 EO98_06010 polC polC EO98_06180 EO98_06180 EO98_06190 EO98_06190 EO98_06220 EO98_06220 EO98_06650 EO98_06650 EO98_06690 EO98_06690 EO98_06695 EO98_06695 leuS leuS EO98_06825 EO98_06825 EO98_06950 EO98_06950 rnz rnz ileS ileS EO98_07095 EO98_07095 EO98_07105 EO98_07105 EO98_07145 EO98_07145 EO98_07165 EO98_07165 EO98_07170 EO98_07170 EO98_07175 EO98_07175 taw2 taw2 rad50 rad50 mre11 mre11 EO98_07590 EO98_07590 EO98_07610 EO98_07610 rpoD rpoD truB truB EO98_07825 EO98_07825 EO98_07855 EO98_07855 EO98_08060 EO98_08060 EO98_08095 EO98_08095 dnaG dnaG rtcA rtcA kptA kptA EO98_08140 EO98_08140 EO98_08190 EO98_08190 EO98_08205 EO98_08205 EO98_08225 EO98_08225 EO98_08325 EO98_08325 EO98_08620 EO98_08620 rpoH rpoH EO98_08825 EO98_08825 EO98_08830 EO98_08830 EO98_08835 EO98_08835 rpoA2 rpoA2 nusA nusA EO98_09080 EO98_09080 EO98_09100 EO98_09100 EO98_09110 EO98_09110 csl4 csl4 rpoL rpoL EO98_09195 EO98_09195 EO98_09235 EO98_09235 cysS cysS EO98_09310 EO98_09310 EO98_09330 EO98_09330 lysS-2 lysS-2 EO98_09345 EO98_09345 EO98_09350 EO98_09350 EO98_09420 EO98_09420 EO98_09440 EO98_09440 serS-2 serS-2 metG metG EO98_09600 EO98_09600 dbh-2 dbh-2 nth-2 nth-2 fen fen EO98_09910 EO98_09910 EO98_09920 EO98_09920 EO98_09980 EO98_09980 EO98_10250 EO98_10250 EO98_10260 EO98_10260 proS proS EO98_10435 EO98_10435 EO98_10445 EO98_10445 tfe tfe rnp1 rnp1 EO98_10920 EO98_10920 EO98_10970 EO98_10970 EO98_11240 EO98_11240 EO98_11275 EO98_11275 EO98_11285 EO98_11285 hisS hisS truA truA EO98_11915 EO98_11915 EO98_12050 EO98_12050 EO98_12195 EO98_12195 rtcB rtcB EO98_12255 EO98_12255 rnp4 rnp4 flpA flpA EO98_12580 EO98_12580 EO98_12780 EO98_12780 mutL mutL mutS mutS EO98_13075 EO98_13075 EO98_13170 EO98_13170 EO98_13415 EO98_13415 tgtA tgtA EO98_13740 EO98_13740 tbp tbp ogt ogt EO98_14225 EO98_14225 dtdA dtdA aspC aspC EO98_14935 EO98_14935 EO98_14955 EO98_14955 EO98_15070 EO98_15070 uvrA uvrA uvrC uvrC uvrB uvrB EO98_15155 EO98_15155 EO98_15185 EO98_15185 EO98_15240 EO98_15240 EO98_15275 EO98_15275 topA topA EO98_15300 EO98_15300 EO98_15335 EO98_15335 EO98_15350 EO98_15350 pheT pheT rnhB rnhB EO98_15635 EO98_15635 hel308 hel308 EO98_15690 EO98_15690 tiaS tiaS radA radA EO98_15855 EO98_15855 cca cca EO98_15925 EO98_15925 EO98_15990 EO98_15990 EO98_16010 EO98_16010 EO98_16025 EO98_16025 EO98_16065 EO98_16065 EO98_16265 EO98_16265 EO98_16275 EO98_16275 endA endA EO98_16380 EO98_16380 EO98_16385 EO98_16385 EO98_16390 EO98_16390 cas1 cas1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
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cas2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (87 aa)
EO98_16415Hypothetical protein; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (200 aa)
EO98_16525Restriction endonuclease or methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
EO98_16900LSM domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
EO98_17280Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
thrSthreonine--tRNA ligase; Catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (635 aa)
EO98_17660Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
EO98_17770Beta-lactamase; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
rfcLReplication protein C; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (609 aa)
EO98_18020Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1013 aa)
EO98_18025Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (428 aa)
EO98_18030Derived by automated computational analysis using gene prediction method: Protein Homology. (504 aa)
EO98_18050Ribonucleotide reductase; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (555 aa)
dnaJMolecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (389 aa)
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (412 aa)
trm1tRNA (guanine-N2)-dimethyltransferase; Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (388 aa)
trmYtRNA (pseudouridine-N1)-methyltransferase; Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs; Belongs to the methyltransferase superfamily. TrmY family. (211 aa)
pus10Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-54 and uracil-55 in the psi GC loop of transfer RNAs. (431 aa)
EO98_18400DNA-directed RNA polymerase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
rsmA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily. (269 aa)
ligDNA ligase; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (568 aa)
EO98_18565Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
EO98_18590Metal-dependent phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
EO98_18690Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1928 aa)
cas1-2CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (405 aa)
cas1-3CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (405 aa)
EO98_19050Arylsulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
EO98_19260O-phospho-L-seryl-tRNA:Cys-tRNA synthase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (454 aa)
EO98_19280Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (249 aa)
EO98_19290Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (365 aa)
EO98_19460Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (85 aa)
EO98_01545Methanogenesis marker protein 11; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
EO98_01490ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
truDPseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (438 aa)
lysSlysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (537 aa)
EO98_00595Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
gltXglutamyl-tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (571 aa)
EO98_00455Replication protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
rps930S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (134 aa)
rpoNDNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family. (62 aa)
rpoKDNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family. (60 aa)
rnjRibonuclease J; An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. Archaeal RNase J subfamily. (447 aa)
EO98_00360H/ACA RNA-protein complex protein Gar1; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
tfbTranscription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). (337 aa)
EO98_00345tRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
EO98_00285Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
EO98_00205Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
priSDNA primase; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play [...] (414 aa)
pelAmRNA surveillance protein Pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (350 aa)
rfcSReplication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (329 aa)
EO98_00040Histone; Derived by automated computational analysis using gene prediction method: Protein Homology. (70 aa)
EO98_01730Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
EO98_01775DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (833 aa)
EO98_01800alanyl-tRNA editing protein AlaX; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
EO98_01850glycyl-tRNA synthetease; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
EO98_01855Hef nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (849 aa)
EO98_01870Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
EO98_01880Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
sepSO-phosphoseryl-tRNA ligase; Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys). (539 aa)
EO98_01895Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
cdc6Cell division control protein 6; Involved in regulation of DNA replication. (373 aa)
mutS2DNA mismatch repair protein MutS; Has ATPase and non-specific DNA-binding activities. Belongs to the DNA mismatch repair MutS family. Archaeal Muts2 subfamily. (707 aa)
EO98_01955DNA repair protein RadB; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
EO98_01965Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (794 aa)
argSarginyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (569 aa)
taw1tRNA-modifying enzyme; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (345 aa)
polBDNA polymerase II; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. (679 aa)
EO98_02105Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
vapCTwitching motility protein PilT; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (130 aa)
rpl7ae50S ribosomal protein L7; Multifunctional RNA-binding protein that recognizes the K- turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C'/D' sRNAs. (120 aa)
rps28e30S ribosomal protein S28; The function of S28E in the ribosome is unknown but the structure shows a variants OB-fold that is found in nucleic acid-binding proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the eukaryotic ribosomal protein eS28 family. (73 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (937 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (634 aa)
top6ADNA topoisomerase VI subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (369 aa)
top6BDNA topoisomerase; Relaxes both positive and negative superturns and exhibits a strong decatenase activity. (621 aa)
EO98_027353'-phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
dbhDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (361 aa)
EO98_02985Endonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
serSseryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily. (502 aa)
EO98_03260Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
EO98_03270Ribosomal biosynthesis protein; Probably involved in the biogenesis of the ribosome. (157 aa)
rrp42RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. (266 aa)
rrp41Exonuclease; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails. (484 aa)
rrp4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome. (260 aa)
rnp3Ribonuclease P protein component 3; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 3 family. (239 aa)
EO98_03345ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (912 aa)
EO98_03360Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (72 aa)
EO98_03375Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (63 aa)
EO98_03395Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (61 aa)
alaSalanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (925 aa)
EO98_03695RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). (437 aa)
pheSphenylalanyl-tRNA synthetase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily. (492 aa)
pylSpyrolysyl-tRNA ligase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG. (502 aa)
EO98_03965Replication protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (341 aa)
EO98_04055Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
EO98_04110DNA-directed RNA polymerase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (104 aa)
pcnDNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. (245 aa)
priLDNA primase; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (371 aa)
EO98_04305Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (624 aa)
EO98_04310Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (611 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily. (869 aa)
EO98_04695Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
EO98_04705Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (297 aa)
EO98_04760Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
EO98_04785Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
EO98_04825Hypothetical protein; RNA-free RNase P that catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. Belongs to the HARP family. (247 aa)
EO98_04845Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
EO98_04910Hypothetical protein; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (344 aa)
EO98_05310Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
EO98_05395SirA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (75 aa)
tyrStyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily. (317 aa)
EO98_05435Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
EO98_05465Recombinase RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
EO98_05480Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
EO98_05725DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (935 aa)
EO98_05765Similar to yeast Dim2p protein that is essential for 40S ribosomal subunit; structural studies show binding to 3' end of 16S rRNA in complex with archaeal IF2 alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (204 aa)
EO98_06010tRNA threonylcarbamoyladenosine biosynthesis protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (363 aa)
polCDNA polymerase II large subunit; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase. (1150 aa)
EO98_06180Chromosomal protein MC1; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
EO98_06190Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
EO98_06220DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (944 aa)
EO98_06650Serine/threonine protein kinase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function. In the N-terminal section; belongs to the KAE1 / TsaD family. (547 aa)
EO98_06690DNA-directed RNA polymerase subunit E; Participates in both the initiation and recycling phases of transcription; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
EO98_06695DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
leuSleucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...] (966 aa)
EO98_06825DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
EO98_06950Replication protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
rnzRibonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (305 aa)
ileSisoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1059 aa)
EO98_07095KaiC; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
EO98_07105Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
EO98_07145Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology. (917 aa)
EO98_07165Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
EO98_07170Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
EO98_07175DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
taw2Methyltransferase; S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S- adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7- aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe). (343 aa)
rad50DNA repair protein Rad50; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily. (1078 aa)
mre11Double-stranded DNA repair protein Mre11; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. (643 aa)
EO98_075902-methylthioadenine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
EO98_07610Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
rpoDDNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (266 aa)
truBH/ACA RNA-protein complex component Cbf5p; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa)
EO98_07825Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
EO98_07855Phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
EO98_08060Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
EO98_08095tRNA-ribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (625 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (518 aa)
rtcARibosomal subunit interface protein; Catalyzes the conversion of 3'-phosphate to a 2',3'-cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps: (A) adenylation of the enzyme by ATP; (B) transfer of adenylate to an RNA-N3'P to produce RNA-N3'PP5'A; (C) and attack of the adjacent 2'-hydroxyl on the 3'-phosphorus in the diester linkage to produce the cyclic end product. The biological role of this enzyme is unknown but it is likely to function in some aspects of cellular RNA processing. (355 aa)
kptARNA 2'-phosphotransferase; Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP-ribose 1''-2''- cyclic phosphate (APPR>P). May function as an ADP-ribosylase. (207 aa)
EO98_08140Replication protein A protects and stabilize the intermediate ssDNA that is generated by the unwinding action of a DNA helicase at the replication fork. In addition, SSBs prevent the formation of secondary structures by single-stranded template DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
EO98_08190Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (134 aa)
EO98_08205Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
EO98_08225Cell division control protein Cdc6; Involved in regulation of DNA replication. (414 aa)
EO98_08325Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
EO98_08620Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
rpoHDNA-directed RNA polymerase subunit H; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoH/eukaryotic RPB5 RNA polymerase subunit family. (78 aa)
EO98_08825DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
EO98_08830DNA-directed RNA polymerase subunit B; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (604 aa)
EO98_08835DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (880 aa)
rpoA2DNA-directed RNA polymerase subunit A'; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (399 aa)
nusATranscription elongation factor NusA; Participates in transcription termination. Belongs to the NusA family. (141 aa)
EO98_09080Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
EO98_09100Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa)
EO98_09110Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
csl4RNA-binding protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs. (328 aa)
rpoLDNA-directed RNA polymerase subunit L; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoL/eukaryotic RPB11/RPC19 RNA polymerase subunit family. (92 aa)
EO98_09195Sep-tRNA:Cys-tRNA ligase; Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L- cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)); Belongs to the SepCysS family. (386 aa)
EO98_09235Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
cysScysteinyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
EO98_09310Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
EO98_09330Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (115 aa)
lysS-2lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (511 aa)
EO98_09345Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (960 aa)
EO98_09350Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (287 aa)
EO98_09420Hypothetical protein; Involved in DNA damage repair; Belongs to the Nre family. (408 aa)
EO98_09440Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
serS-2seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (421 aa)
metGmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (711 aa)
EO98_09600Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
dbh-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. (365 aa)
nth-2Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (234 aa)
fenFlap endonuclease-1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (338 aa)
EO98_09910Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (154 aa)
EO98_09920Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (85 aa)
EO98_09980KaiC; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
EO98_10250Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
EO98_10260Sulfur reduction protein DsrE; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (480 aa)
EO98_10435Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa)
EO98_10445Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
tfeTranscription factor; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to [...] (164 aa)
rnp1Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends; Belongs to the eukaryotic/archaeal RNase P protein component 1 family. (110 aa)
EO98_10920ATP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (109 aa)
EO98_10970Endonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
EO98_11240Queuine tRNA-ribosyltransferase containing PUA domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
EO98_11275DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa)
EO98_11285Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
hisShistidyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (413 aa)
truAPseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family. (269 aa)
EO98_11915RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
EO98_12050Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
EO98_12195Archease; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. (146 aa)
rtcBtRNA-splicing ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RtcB family. (500 aa)
EO98_12255Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
rnp4Ribonuclease P; Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (107 aa)
flpAFibrillin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (227 aa)
EO98_12580Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
EO98_127802-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
mutLDNA mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (732 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (900 aa)
EO98_13075Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
EO98_13170Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
EO98_13415RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
tgtA7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (490 aa)
EO98_13740Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
tbpTranscription factor; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (183 aa)
ogtCysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (158 aa)
EO98_14225Metal-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
dtdAD-tyrosyl-tRNA(Tyr) deacylase; D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo. (298 aa)
aspCaspartate--tRNA ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn). (444 aa)
EO98_14935ACT domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0237 family. (92 aa)
EO98_14955tRNA 2'-O-methylase; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family. (177 aa)
EO98_15070Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (993 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (516 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (670 aa)
EO98_15155Methionine-10+; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
EO98_15185Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (93 aa)
EO98_15240Chromosomal protein MC1; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
EO98_15275mRNA 3'-end processing factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (751 aa)
EO98_15300Hypothetical protein; Probable pre-rRNA processing protein involved in ribosome biogenesis; Belongs to the TSR3 family. (173 aa)
EO98_15335Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
EO98_15350Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
pheTphenylalanine--tRNA ligase; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (247 aa)
EO98_15635Small nuclear ribonucleoprotein; Enables 3` processing of polyadenylated mRNAs and tRNA precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the snRNP Sm proteins family. (72 aa)
hel308Extensin; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (730 aa)
EO98_15690mRNA 3'-end processing factor; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
tiaStRNA(Ile2) 2-agmatinylcytidine synthetase; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA. (428 aa)
radADNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (325 aa)
EO98_15855Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
ccaCCA-adding protein; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. (454 aa)
EO98_159258-oxoguanine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
EO98_15990N-6 DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
EO98_16010Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
EO98_16025DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1054 aa)
EO98_16065uracil-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
EO98_16265Chromosomal protein MC1; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
EO98_16275Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
endARibonuclease BN; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp. (350 aa)
EO98_16380Exoribonuclease II; Derived by automated computational analysis using gene prediction method: Protein Homology. (591 aa)
EO98_16385CRISPR-associated protein Cas3; Derived by automated computational analysis using gene prediction method: Protein Homology. (740 aa)
EO98_16390CRISPR-associated protein Cas5; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
cas1CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (333 aa)
Your Current Organism:
Methanosarcina sp. 2HT1A6
NCBI taxonomy Id: 1483599
Other names: M. sp. 2.H.T.1A.6, Methanosarcina sp. 2.H.T.1A.6
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