node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APW41796.1 | apt | RS694_04030 | RS694_20160 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.900 |
APW41796.1 | gmk | RS694_04030 | RS694_04445 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
APW41796.1 | guaA | RS694_04030 | RS694_10220 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.900 |
APW41796.1 | guaB | RS694_04030 | RS694_10215 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.900 |
APW41796.1 | guaC | RS694_04030 | RS694_06495 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.900 |
APW41796.1 | purA | RS694_04030 | RS694_11295 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.900 |
APW41796.1 | udk | RS694_04030 | RS694_14360 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
APW41796.1 | upp | RS694_04030 | RS694_09555 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
APW41796.1 | ushA | RS694_04030 | RS694_15450 | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional metallophosphatase/5'-nucleotidase; Catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. | 0.900 |
apt | APW41796.1 | RS694_20160 | RS694_04030 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
apt | gmk | RS694_20160 | RS694_04445 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.969 |
apt | guaA | RS694_20160 | RS694_10220 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.995 |
apt | guaB | RS694_20160 | RS694_10215 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.561 |
apt | guaC | RS694_20160 | RS694_06495 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanosine monophosphate reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides; Belongs to the IMPDH/GMPR family. GuaC type 2 subfamily. | 0.933 |
apt | purA | RS694_20160 | RS694_11295 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.642 |
apt | upp | RS694_20160 | RS694_09555 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.478 |
apt | ushA | RS694_20160 | RS694_15450 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Bifunctional metallophosphatase/5'-nucleotidase; Catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. | 0.927 |
gmk | APW41796.1 | RS694_04445 | RS694_04030 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
gmk | apt | RS694_04445 | RS694_20160 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.969 |
gmk | guaA | RS694_04445 | RS694_10220 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthetase; Catalyzes the synthesis of GMP from XMP. | 0.970 |