STRINGSTRING
APW42367.1 APW42367.1 APW42365.1 APW42365.1 APW42364.1 APW42364.1 lpxB lpxB lpxA lpxA fabZ fabZ lpxD lpxD APW42308.1 APW42308.1 APW42041.1 APW42041.1 APW42040.1 APW42040.1 APW41935.1 APW41935.1 fbp fbp APW41938.1 APW41938.1 APW41937.1 APW41937.1 APW44692.1 APW44692.1 APW41936.1 APW41936.1 APW44988.1 APW44988.1 APW44691.1 APW44691.1 APW41934.1 APW41934.1 APW41926.1 APW41926.1 pgi pgi glmU glmU APW41730.1 APW41730.1 APW41659.1 APW41659.1 APW41623.1 APW41623.1 APW41507.1 APW41507.1 APW41311.1 APW41311.1 APW41292.1 APW41292.1 pckG pckG APW44628.1 APW44628.1 APW41098.1 APW41098.1 APW44185.1 APW44185.1 APW44192.1 APW44192.1 APW43120.1 APW43120.1 APW44839.1 APW44839.1 lpxH lpxH kdsA kdsA tpiA tpiA APW43723.1 APW43723.1 gpmA gpmA APW44193.1 APW44193.1 APW44198.1 APW44198.1 APW44309.1 APW44309.1 APW44983.1 APW44983.1 APW43963.1 APW43963.1 APW43964.1 APW43964.1 lpxC lpxC APW44163.1 APW44163.1 APW44957.1 APW44957.1 APW44165.1 APW44165.1 APW43962.1 APW43962.1 APW44169.1 APW44169.1 APW44172.1 APW44172.1 APW44179.1 APW44179.1 APW44184.1 APW44184.1 APW43104.1 APW43104.1 APW42763.1 APW42763.1 APW44791.1 APW44791.1 APW42583.1 APW42583.1 lpxK lpxK kdsB kdsB APW42380.1 APW42380.1 APW44601.1 APW44601.1 APW44555.1 APW44555.1 APW44551.1 APW44551.1 APW44434.1 APW44434.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APW42367.1Histidine phosphatase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
APW42365.1Alpha-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
APW42364.1UDP-2,3-diacylglucosamine hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (377 aa)
lpxAacyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (267 aa)
fabZbeta-hydroxyacyl-ACP dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
lpxDUDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. (324 aa)
APW42308.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (462 aa)
APW42041.13-deoxy-D-manno-octulosonic acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (434 aa)
APW42040.1Lipopolysaccharide heptosyltransferase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
APW41935.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (346 aa)
fbpFructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (336 aa)
APW41938.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (295 aa)
APW41937.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1102 aa)
APW44692.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
APW41936.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (451 aa)
APW44988.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
APW44691.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
APW41934.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
APW41926.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (522 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (460 aa)
APW41730.1Mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
APW41659.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (668 aa)
APW41623.1Erythromycin biosynthesis sensory transduction protein eryC1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (364 aa)
APW41507.1Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa)
APW41311.1Lipopolysaccharide heptosyltransferase II; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
APW41292.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
pckGPhosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (625 aa)
APW44628.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
APW41098.1Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
APW44185.1UDP-N-acetylglucosamine 4,6-dehydratase (inverting); Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
APW44192.1Acetylneuraminic acid synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
APW43120.1Ribulose 1,5-bisphosphate carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
APW44839.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
lpxHUDP-2,3-diacylglucosamine hydrolase; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (263 aa)
kdsA3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. (284 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (247 aa)
APW43723.1Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (303 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (247 aa)
APW44193.1Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
APW44198.1Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family. (475 aa)
APW44309.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
APW44983.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1729 aa)
APW43963.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
APW43964.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (587 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (307 aa)
APW44163.1Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (646 aa)
APW44957.1UDP-phosphate galactose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
APW44165.1Glycosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
APW43962.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
APW44169.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (340 aa)
APW44172.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
APW44179.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
APW44184.1UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DegT/DnrJ/EryC1 family. (385 aa)
APW43104.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
APW42763.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (400 aa)
APW44791.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
APW42583.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (801 aa)
lpxKTetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (349 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (259 aa)
APW42380.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
APW44601.13-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
APW44555.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transketolase family. (689 aa)
APW44551.12,5-didehydrogluconate reductase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
APW44434.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
Your Current Organism:
Rhodoferax saidenbachensis
NCBI taxonomy Id: 1484693
Other names: CCUG 57711, DSM 22694, R. saidenbachensis, Rhodoferax saidenbachensis Kaden et al. 2014, strain ED16
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