STRINGSTRING
RS694_14110 RS694_14110 APW41148.1 APW41148.1 APW41340.1 APW41340.1 APW44643.1 APW44643.1 hemE hemE APW41711.1 APW41711.1 APW41870.1 APW41870.1 cobD cobD APW42455.1 APW42455.1 hemH hemH APW42554.1 APW42554.1 APW42682.1 APW42682.1 APW42684.1 APW42684.1 APW42687.1 APW42687.1 APW42688.1 APW42688.1 APW42692.1 APW42692.1 APW44779.1 APW44779.1 cobD-2 cobD-2 cobQ cobQ cobT cobT cobS cobS hemF hemF APW42841.1 APW42841.1 cobH cobH APW42992.1 APW42992.1 APW42993.1 APW42993.1 APW44815.1 APW44815.1 APW42994.1 APW42994.1 APW42995.1 APW42995.1 APW42996.1 APW42996.1 APW42997.1 APW42997.1 APW43506.1 APW43506.1 APW43656.1 APW43656.1 APW43657.1 APW43657.1 APW43658.1 APW43658.1 hemC hemC hemA hemA APW43942.1 APW43942.1 ctaB ctaB APW44005.1 APW44005.1 hemL hemL APW44235.1 APW44235.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RS694_14110DNA-binding protein YbiB; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (268 aa)
APW41148.1ATP:cob(I)alamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
APW41340.1Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (338 aa)
APW44643.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (379 aa)
APW41711.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
APW41870.1YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (416 aa)
cobDCobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (306 aa)
APW42455.1Oxygen-independent coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (464 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (363 aa)
APW42554.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
APW42682.1Cobyrinic acid a,c-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (473 aa)
APW42684.1Adenosylcobinamide-phosphate guanylyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (194 aa)
APW42687.1Cobalt transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
APW42688.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (189 aa)
APW42692.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
APW44779.1Magnesium chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
cobD-2Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (324 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (524 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (361 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (268 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (308 aa)
APW42841.1Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
cobHCatalyzes the interconversion of precorrin-8X and hydrogenobyrinate; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
APW42992.1Precorrin-2 C(20)-methyltransferase; Methylates precorrin-2 at the C-20 position to produce precorrin-3A. (243 aa)
APW42993.1precorrin-3B C(17)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
APW44815.1precorrin-6A reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
APW42994.1Cobalamin biosynthesis bifunctional protein CbiET; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa)
APW42995.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
APW42996.1Precorrin-4 C(11)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (262 aa)
APW42997.1precorrin-6A synthase (deacetylating); Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
APW43506.1Carotenoid 1,2-hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
APW43656.1Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
APW43657.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
APW43658.1Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (264 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (307 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (419 aa)
APW43942.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (301 aa)
APW44005.1Heme A synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
hemLAspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
APW44235.1Aspartate aminotransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (459 aa)
Your Current Organism:
Rhodoferax saidenbachensis
NCBI taxonomy Id: 1484693
Other names: CCUG 57711, DSM 22694, R. saidenbachensis, Rhodoferax saidenbachensis Kaden et al. 2014, strain ED16
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