(59 nodes) Reverse transcriptase/Diguanylate cyclase domain network (Rhodoferax saidenbachensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APW42132.1	Diguanylate cyclase response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
	APW41103.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
	APW41163.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
	APW41239.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
	APW41296.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa)
	APW44644.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (832 aa)
	APW41470.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
	APW41722.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
	APW41833.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
	APW41853.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
	APW41861.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
	APW41932.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
	APW41976.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
	APW42031.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (890 aa)
	APW42134.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
	APW42137.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
	APW42158.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
	APW44724.1	REC domain-containing phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (571 aa)
	APW42307.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
	APW42369.1	Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (600 aa)
	APW42429.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
	APW42457.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
	APW42483.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
	APW42677.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (686 aa)
	APW42700.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa)
	APW42872.1	GGDEF-domain containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (586 aa)
	APW42937.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (934 aa)
	APW42978.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)
	APW43039.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)
	APW44833.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
	RS694_12085	Two-component system response regulator; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (710 aa)
	APW43257.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (703 aa)
	APW43318.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1365 aa)
	APW43427.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
	APW43565.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (985 aa)
	APW43566.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (979 aa)
	APW43571.1	GGDEF domain-containing response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
	APW43655.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (358 aa)
	dinB	DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (416 aa)
	APW43704.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
	APW43762.1	Bifunctional diguanylate cyclase/phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (783 aa)
	APW44905.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (767 aa)
	APW43849.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
	APW43976.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (778 aa)
	APW44932.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
	APW44052.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (585 aa)
	APW44053.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
	APW44951.1	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1126 aa)
	APW44128.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (702 aa)
	APW44227.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (875 aa)
	APW44272.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1054 aa)
	APW44320.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
	APW44401.1	Diguanylate cyclase AdrA; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa)
	APW44437.1	Diguanylate cyclase response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
	APW44511.1	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
	APW44515.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
	APW44538.1	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
	APW44584.1	GGDEF-domain containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (688 aa)
	APW44593.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (713 aa)

Your Current Organism:

Rhodoferax saidenbachensis

NCBI taxonomy Id: 1484693
Other names: CCUG 57711, DSM 22694, R. saidenbachensis, Rhodoferax saidenbachensis Kaden et al. 2014, strain ED16

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APW41103.1	APW41722.1	RS694_00095	RS694_03575	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.421
APW41103.1	APW41861.1	RS694_00095	RS694_04425	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.418
APW41103.1	APW41932.1	RS694_00095	RS694_04825	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.481
APW41103.1	APW42031.1	RS694_00095	RS694_05435	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.467
APW41103.1	APW42137.1	RS694_00095	RS694_06045	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
APW41103.1	APW42677.1	RS694_00095	RS694_09125	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.416
APW41103.1	APW42872.1	RS694_00095	RS694_10225	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF-domain containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.508
APW41103.1	APW42937.1	RS694_00095	RS694_10590	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.410
APW41103.1	APW42978.1	RS694_00095	RS694_10830	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427
APW41103.1	APW43039.1	RS694_00095	RS694_11190	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.597
APW41103.1	APW43565.1	RS694_00095	RS694_14170	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.462
APW41103.1	APW43566.1	RS694_00095	RS694_14175	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.461
APW41103.1	APW43571.1	RS694_00095	RS694_14210	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF domain-containing response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
APW41103.1	APW43762.1	RS694_00095	RS694_15280	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bifunctional diguanylate cyclase/phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.428
APW41103.1	APW43976.1	RS694_00095	RS694_16510	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.435
APW41103.1	APW44227.1	RS694_00095	RS694_17955	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.435
APW41103.1	APW44272.1	RS694_00095	RS694_18230	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Sensor domain-containing diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
APW41103.1	APW44593.1	RS694_00095	RS694_20095	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.634
APW41103.1	APW44644.1	RS694_00095	RS694_01925	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.406
APW41103.1	APW44724.1	RS694_00095	RS694_06190	GGDEF domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	REC domain-containing phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.542