STRINGSTRING
SHF65365.1 SHF65365.1 SHE36016.1 SHE36016.1 SHE37183.1 SHE37183.1 SHE37360.1 SHE37360.1 SHE37964.1 SHE37964.1 SHE38304.1 SHE38304.1 SHE38361.1 SHE38361.1 SHE38687.1 SHE38687.1 guaB guaB ilvC ilvC hisD hisD zwf zwf SHE50282.1 SHE50282.1 SHE50868.1 SHE50868.1 SHE63749.1 SHE63749.1 SHE63784.1 SHE63784.1 pdxA pdxA SHE69611.1 SHE69611.1 SHE72933.1 SHE72933.1 dxr dxr SHE60970.1 SHE60970.1 SHE61030.1 SHE61030.1 SHE77357.1 SHE77357.1 SHE92525.1 SHE92525.1 SHE96363.1 SHE96363.1 lcdH lcdH SHE90241.1 SHE90241.1 SHF15503.1 SHF15503.1 SHF16839.1 SHF16839.1 SHF18317.1 SHF18317.1 SHF18485.1 SHF18485.1 SHF18621.1 SHF18621.1 SHF12484.1 SHF12484.1 SHF19667.1 SHF19667.1 SHF20178.1 SHF20178.1 SHF20293.1 SHF20293.1 SHF20580.1 SHF20580.1 SHF20678.1 SHF20678.1 SHF20742.1 SHF20742.1 hisD-2 hisD-2 mdh mdh gpsA gpsA leuB leuB SHF29820.1 SHF29820.1 SHF45317.1 SHF45317.1 aroE aroE SHF47498.1 SHF47498.1 SHF42992.1 SHF42992.1 SHF48012.1 SHF48012.1 SHF53381.1 SHF53381.1 SHF54856.1 SHF54856.1 hisD-3 hisD-3 SHF67914.1 SHF67914.1 SHF70188.1 SHF70188.1 SHF71743.1 SHF71743.1 SHF71979.1 SHF71979.1 SHF74753.1 SHF74753.1 SHF75050.1 SHF75050.1 SHF75113.1 SHF75113.1 SHF75265.1 SHF75265.1 murB murB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHF65365.1D-3-phosphoglycerate dehydrogenase. (318 aa)
SHE36016.13-hydroxyisobutyrate dehydrogenase. (299 aa)
SHE37183.1Hydroxypyruvate reductase. (443 aa)
SHE37360.1Threonine dehydrogenase. (327 aa)
SHE37964.1Shikimate dehydrogenase. (276 aa)
SHE38304.1Predicted dehydrogenase. (352 aa)
SHE38361.1Predicted dehydrogenase. (378 aa)
SHE38687.13-hydroxyisobutyrate dehydrogenase. (293 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (482 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
hisDSulfopropanediol 3-dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (443 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (483 aa)
SHE50282.1Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (388 aa)
SHE50868.13-hydroxyisobutyrate dehydrogenase. (318 aa)
SHE63749.1Predicted dehydrogenase. (334 aa)
SHE63784.13-isopropylmalate dehydrogenase. (362 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (321 aa)
SHE69611.1Alcohol dehydrogenase. (345 aa)
SHE72933.1Isocitrate dehydrogenase (NADP); Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (391 aa)
SHE60970.1Short chain enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (703 aa)
SHE61030.13-hydroxyisobutyrate dehydrogenase. (298 aa)
SHE77357.13-hydroxyisobutyrate dehydrogenase. (291 aa)
SHE92525.13-hydroxybutyryl-CoA dehydrogenase. (291 aa)
SHE96363.1Predicted dehydrogenase. (331 aa)
lcdHCarnitine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (480 aa)
SHE90241.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa)
SHF15503.1Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)
SHF16839.1Glyoxylate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (328 aa)
SHF18317.1Homoserine dehydrogenase. (427 aa)
SHF18485.13-hydroxyisobutyrate dehydrogenase. (289 aa)
SHF18621.1Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). (764 aa)
SHF12484.1L-idonate 5-dehydrogenase. (343 aa)
SHF19667.13-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase. (729 aa)
SHF20178.1Lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
SHF20293.12-hydroxy-3-oxopropionate reductase. (294 aa)
SHF20580.1Predicted dehydrogenase. (336 aa)
SHF20678.12-hydroxy-3-oxopropionate reductase. (293 aa)
SHF20742.1Predicted dehydrogenase. (338 aa)
hisD-2Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa)
mdhMalate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
gpsAGlycerol-3-phosphate dehydrogenase (NAD(P)+); Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (323 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (368 aa)
SHF29820.1Dihydrofolate reductase. (177 aa)
SHF45317.1Malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+). (785 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (277 aa)
SHF47498.1S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (422 aa)
SHF42992.1UDP-N-acetyl-D-galactosamine dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (452 aa)
SHF48012.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa)
SHF53381.1Uronate dehydrogenase. (276 aa)
SHF54856.1Zn-dependent alcohol dehydrogenase. (362 aa)
hisD-3Sulfopropanediol 3-dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
SHF67914.1D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
SHF70188.1dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (288 aa)
SHF71743.1Predicted dehydrogenase. (365 aa)
SHF71979.1UDP-glucose dehydrogenase. (443 aa)
SHF74753.1Predicted dehydrogenase. (377 aa)
SHF75050.1Predicted dehydrogenase. (384 aa)
SHF75113.1Predicted dehydrogenase. (367 aa)
SHF75265.1Myo-inositol 2-dehydrogenase. (328 aa)
murBUDP-N-acetylmuramate dehydrogenase; Cell wall formation. (305 aa)
Your Current Organism:
Litoreibacter ascidiaceicola
NCBI taxonomy Id: 1486859
Other names: CECT 8539, DSM 100566, KCTC 42050, L. ascidiaceicola, Litoreibacter ascidiaceicola Kim et al. 2014, Litoreibacter sp. RSS4-C1, strain RSS4-C1
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