STRINGSTRING
ALR90427.1 ALR90427.1 ALR90499.1 ALR90499.1 ALP91714.1 ALP91714.1 ALP91877.1 ALP91877.1 ALP91689.1 ALP91689.1 ALP91682.1 ALP91682.1 ALP91681.1 ALP91681.1 ALP91874.1 ALP91874.1 ALP91657.1 ALP91657.1 ALP91656.1 ALP91656.1 ALP91655.1 ALP91655.1 ALP91581.1 ALP91581.1 ALP91541.1 ALP91541.1 ALP91527.1 ALP91527.1 ALP91461.1 ALP91461.1 udp udp deoD-2 deoD-2 ALP91262.1 ALP91262.1 hisG hisG hisH hisH hisF hisF ALP91126.1 ALP91126.1 tagO tagO glgB-2 glgB-2 queA queA tgt tgt apt apt ALP90965.1 ALP90965.1 ALP90964.1 ALP90964.1 ALP90959.1 ALP90959.1 ftsW ftsW pyrR pyrR lgt-2 lgt-2 ALP90778.1 ALP90778.1 ALP90567.1 ALP90567.1 xpt xpt trpD trpD ALP90187.1 ALP90187.1 ALP90095.1 ALP90095.1 ALP89935.1 ALP89935.1 mltG mltG purF purF ALP89841.1 ALP89841.1 pyrE pyrE ALP89815.1 ALP89815.1 ALP89814.1 ALP89814.1 ALP89778.1 ALP89778.1 hpt-2 hpt-2 ALP89741.1 ALP89741.1 deoD deoD nadC nadC deoA deoA ALP91805.1 ALP91805.1 malQ-2 malQ-2 murG murG ALP89378.1 ALP89378.1 ALP89376.1 ALP89376.1 ALP89372.1 ALP89372.1 mrdB mrdB ALP89305.1 ALP89305.1 upp upp ALP89272.1 ALP89272.1 ALP89258.1 ALP89258.1 ALP89255.1 ALP89255.1 ALP89229.1 ALP89229.1 ALP89212.1 ALP89212.1 ALP89150.1 ALP89150.1 malQ malQ hpt hpt lgt lgt cobT cobT glgB glgB glgA glgA ALP88720.1 ALP88720.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ALR90427.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
ALR90499.1Peptidase M56; Derived by automated computational analysis using gene prediction method: Protein Homology. (613 aa)
ALP91714.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3187 aa)
ALP91877.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ALP91689.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
ALP91682.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
ALP91681.1Rhamnosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
ALP91874.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
ALP91657.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
ALP91656.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
ALP91655.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ALP91581.1Cellobiose phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (900 aa)
ALP91541.1Glycosyltransferase WbuB; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
ALP91527.1Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
ALP91461.1Glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
udpUridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (261 aa)
deoD-2Purine nucleoside phosphorylase DeoD-type; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
ALP91262.1Purine-nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (273 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (209 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (206 aa)
hisFImidazole glycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (253 aa)
ALP91126.1Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (492 aa)
tagOUDP-phosphate N-acetylgalactosaminyl-1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
glgB-2Glycogen-branching enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (341 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (378 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (172 aa)
ALP90965.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
ALP90964.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
ALP90959.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
ftsWRod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (379 aa)
pyrRTranscriptional regulator; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (182 aa)
lgt-2Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (256 aa)
ALP90778.1Exopolysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
ALP90567.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (191 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (335 aa)
ALP90187.1Glycogen debranching protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (660 aa)
ALP90095.1Exopolysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ALP89935.1Laccase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (246 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (341 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (470 aa)
ALP89841.1Exopolysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (224 aa)
ALP89815.1Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
ALP89814.1Glycosyl transferase group 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ALP89778.1Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
hpt-2Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (174 aa)
ALP89741.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (837 aa)
deoDPurine nucleoside phosphorylase DeoD-type; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
nadCNicotinate-nucleotide pyrophosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (279 aa)
deoAThymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)
ALP91805.1Maltodextrin phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (786 aa)
malQ-24-alpha-glucanotransferase; Amylomaltase; acts to release glucose from maltodextrins; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
murGUndecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (357 aa)
ALP89378.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ALP89376.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
ALP89372.1Rod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (375 aa)
mrdBRod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (376 aa)
ALP89305.1Competence protein ComF; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
ALP89272.1Galactosyldiacylglycerol synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
ALP89258.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
ALP89255.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
ALP89229.1D-galactosyl-beta-1-3-N-acetyl-D-hexosamine phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (719 aa)
ALP89212.1Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
ALP89150.1Maltose phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (752 aa)
malQ4-alpha-glucanotransferase; Amylomaltase; acts to release glucose from maltodextrins; Derived by automated computational analysis using gene prediction method: Protein Homology. (520 aa)
hptHypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (256 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (361 aa)
glgBGlycogen-branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (671 aa)
glgAGlycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (479 aa)
ALP88720.1Dolichyl-phosphate-mannose--protein mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
Your Current Organism:
Clostridium butyricum
NCBI taxonomy Id: 1492
Other names: ATCC 19398, Amylobacter navicula, Bacillus amylobacter, Bacillus butyricus, Bacillus navicula, Bacterium navicula, C. butyricum, CCUG 4217, CIP 103309, Clostridium kainantoi, Clostridium naviculum, Clostridium pseudotetanicum, DSM 10702, HAMBI 482, IAM 14194, IFO 13949, Metallacter amylobacter, NBRC 13949, NCCB 89156, NCIB 7423, NCIMB 7423, NCTC 7423, VPI 3266
Server load: low (22%) [HD]