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murB murB ALP88700.1 ALP88700.1 ALP88701.1 ALP88701.1 glgD glgD glgC glgC ALP88733.1 ALP88733.1 ALP88734.1 ALP88734.1 ALP88789.1 ALP88789.1 murA murA glmU glmU glmM glmM glmS glmS ALP89178.1 ALP89178.1 nagA nagA pgi pgi nagA-2 nagA-2 mnaA mnaA murA-2 murA-2 rfbF rfbF ALP89375.1 ALP89375.1 ALP89810.1 ALP89810.1 ALP90968.1 ALP90968.1 ALP90969.1 ALP90969.1 ALP91340.1 ALP91340.1 galK galK galE galE galT galT nagE nagE manA manA ALP91474.1 ALP91474.1 nanE nanE ALP91479.1 ALP91479.1 ALP91539.1 ALP91539.1 ALP91543.1 ALP91543.1 nanE-2 nanE-2 nanA nanA galE-2 galE-2 ATN24_16360 ATN24_16360 ALP91876.1 ALP91876.1 ptbA ptbA ALR90397.1 ALR90397.1 ALR90398.1 ALR90398.1 ALR90399.1 ALR90399.1 ALR90506.1 ALR90506.1 nagB nagB murQ murQ ALR90722.1 ALR90722.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (304 aa)
ALP88700.1UDP-N-acetyl-D-glucosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)
ALP88701.1Hexapeptide transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
glgDGlucose-1-phosphate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (387 aa)
ALP88733.1PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa)
ALP88734.1PTS glucose transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
ALP88789.1Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (456 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (448 aa)
glmSGlutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (608 aa)
ALP89178.1Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
nagAN-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa)
nagA-2N-acetylglucosamine-6-phosphate deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
mnaAUDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (382 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
rfbFGlucose-1-phosphate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
ALP89375.1Sugar dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
ALP89810.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (575 aa)
ALP90968.1Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
ALP90969.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
ALP91340.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (389 aa)
galEUDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)
galTGalactose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
nagEPTS glucose transporter subunit IIBC; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
manAMannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ALP91474.1Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (232 aa)
ALP91479.1Dihydrodipicolinate synthase family protein; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. Belongs to the DapA family. (309 aa)
ALP91539.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
ALP91543.1UDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (354 aa)
nanE-2N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (231 aa)
nanAN-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. (295 aa)
galE-2UDP-glucose 4-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (329 aa)
ATN24_16360Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
ALP91876.1UDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
ptbAPTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (161 aa)
ALR90397.1PTS mannose transporter subunit EIIAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
ALR90398.1PTS mannose/fructose/sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
ALR90399.1PTS mannose family transporter subunit IID; Hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
ALR90506.1Xylan 1,4-beta-xylosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 43 family. (548 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. (251 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (301 aa)
ALR90722.1PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
Your Current Organism:
Clostridium butyricum
NCBI taxonomy Id: 1492
Other names: ATCC 19398, Amylobacter navicula, Bacillus amylobacter, Bacillus butyricus, Bacillus navicula, Bacterium navicula, C. butyricum, CCUG 4217, CIP 103309, Clostridium kainantoi, Clostridium naviculum, Clostridium pseudotetanicum, DSM 10702, HAMBI 482, IAM 14194, IFO 13949, Metallacter amylobacter, NBRC 13949, NCCB 89156, NCIB 7423, NCIMB 7423, NCTC 7423, VPI 3266
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