STRINGSTRING
ilvC ilvC GY26_02580 GY26_02580 GY26_02570 GY26_02570 GY26_01355 GY26_01355 aroE aroE GY26_09815 GY26_09815 GY26_09840 GY26_09840 GY26_09920 GY26_09920 dapB dapB GY26_20310 GY26_20310 GY26_13590 GY26_13590 gapA-2 gapA-2 zwf-2 zwf-2 GY26_15600 GY26_15600 GY26_15335 GY26_15335 GY26_15150 GY26_15150 GY26_14775 GY26_14775 GY26_01110 GY26_01110 GY26_11655 GY26_11655 proA proA GY26_12645 GY26_12645 GY26_14635 GY26_14635 GY26_14445 GY26_14445 GY26_14155 GY26_14155 GY26_14025 GY26_14025 hldD hldD GY26_13845 GY26_13845 GY26_18670 GY26_18670 GY26_18800 GY26_18800 GY26_18920 GY26_18920 zwf zwf GY26_08185 GY26_08185 dxr dxr gapA gapA hemA hemA pntB pntB asd asd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
GY26_02580Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
GY26_025703-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
GY26_01355Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (270 aa)
GY26_09815NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the WrbA family. (214 aa)
GY26_09840Sulfite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
GY26_09920Glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa)
GY26_203103-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
GY26_13590FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
gapA-2Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (494 aa)
GY26_15600Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
GY26_15335Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
GY26_15150Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
GY26_14775Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (368 aa)
GY26_01110Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
GY26_11655Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (862 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (427 aa)
GY26_12645Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (491 aa)
GY26_146356-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
GY26_14445Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
GY26_14155Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (63 aa)
GY26_14025Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
hldDADP-L-glycero-D-manno-heptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (323 aa)
GY26_13845Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (176 aa)
GY26_186702-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
GY26_18800NAD(P)H:quinone oxidoreductase; Catalyzes the transfer of electrons from NADH to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
GY26_18920Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (523 aa)
GY26_081856-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (396 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (345 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (424 aa)
pntBPyridine nucleotide transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (480 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (371 aa)
Your Current Organism:
Gammaproteobacteria bacterium MFB021
NCBI taxonomy Id: 1492922
Other names: G. bacterium MFB021, bacterium MFB021
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