STRINGSTRING
GY26_16505 GY26_16505 GY26_00255 GY26_00255 GY26_00300 GY26_00300 GY26_00350 GY26_00350 GY26_00355 GY26_00355 GY26_00365 GY26_00365 GY26_00370 GY26_00370 GY26_00390 GY26_00390 GY26_00950 GY26_00950 secB secB GY26_01665 GY26_01665 GY26_02185 GY26_02185 GY26_02630 GY26_02630 secE secE secY secY GY26_03190 GY26_03190 clpB clpB GY26_03295 GY26_03295 GY26_03920 GY26_03920 GY26_04315 GY26_04315 GY26_05000 GY26_05000 GY26_05510 GY26_05510 GY26_09080 GY26_09080 GY26_09090 GY26_09090 GY26_09095 GY26_09095 ssaR ssaR GY26_09105 GY26_09105 GY26_09110 GY26_09110 fliI fliI clpA clpA yidC yidC GY26_10385 GY26_10385 GY26_10595 GY26_10595 GY26_10600 GY26_10600 GY26_10605 GY26_10605 secA secA ftsY ftsY GY26_11720 GY26_11720 GY26_11900 GY26_11900 GY26_12305 GY26_12305 GY26_12920 GY26_12920 GY26_13265 GY26_13265 GY26_13285 GY26_13285 GY26_13915 GY26_13915 GY26_15000 GY26_15000 ftsB ftsB GY26_15230 GY26_15230 ffh ffh GY26_16365 GY26_16365 GY26_16380 GY26_16380 GY26_16385 GY26_16385 tatA tatA tatC tatC GY26_16500 GY26_16500 GY26_16510 GY26_16510 GY26_16515 GY26_16515 secF secF secD secD yajC yajC GY26_17145 GY26_17145 GY26_17945 GY26_17945 GY26_19340 GY26_19340 GY26_19795 GY26_19795 GY26_20465 GY26_20465
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GY26_16505General secretion pathway protein GspE; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa)
GY26_00255Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
GY26_00300ATPase AAA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (886 aa)
GY26_00350Type VI secretion system protein ImpK; Derived by automated computational analysis using gene prediction method: Protein Homology. (237 aa)
GY26_00355ImcF-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1331 aa)
GY26_00365Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (830 aa)
GY26_00370Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
GY26_00390Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (102 aa)
GY26_00950Secretion protein HlyD; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
secBPreprotein translocase subunit SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (160 aa)
GY26_01665Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
GY26_02185Type III secretion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (666 aa)
GY26_02630Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (122 aa)
secYPreprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (444 aa)
GY26_03190Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
clpBProtein disaggregation chaperone; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (861 aa)
GY26_03295Phage late control protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
GY26_03920Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)
GY26_04315Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
GY26_05000Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (644 aa)
GY26_05510Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
GY26_09080Translocation protein in type III secretion system, RhcU; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
GY26_09090Type III secretion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
GY26_09095Type III secretion protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
ssaRType III secretion system protein SsaR; Part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
GY26_09105Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa)
GY26_09110Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (160 aa)
fliIATP synthase; Involved in type III protein export during flagellum assembly; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
clpAClp protease ClpX; ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (754 aa)
yidCMembrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (561 aa)
GY26_10385Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
GY26_10595General secretion pathway protein GspE; Derived by automated computational analysis using gene prediction method: Protein Homology. (575 aa)
GY26_10600Type II secretion system protein F; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
GY26_10605Methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (278 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (913 aa)
ftsYCell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (496 aa)
GY26_11720Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
GY26_11900Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. (789 aa)
GY26_12305Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
GY26_12920Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
GY26_13265Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (219 aa)
GY26_13285Type II secretion system protein I/J; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa)
GY26_13915Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. (886 aa)
GY26_15000Type I secretion protein TolC; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (106 aa)
GY26_15230Hemolysin secretion protein D; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
ffhRNA-binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components; Belongs to t [...] (473 aa)
GY26_16365Type II and III secretion system protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (702 aa)
GY26_16380Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
GY26_16385Pilus assembly protein PilM; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
tatAPreprotein translocase subunit TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (89 aa)
tatCTwin-arginine protein translocation system subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (257 aa)
GY26_16500General secretion pathway protein GspD; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
GY26_16510General secretion pathway protein GspF; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
GY26_16515General secretion pathway protein GspG; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
secFPreprotein translocase subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (303 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (615 aa)
yajCPreprotein translocase subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
GY26_17145Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
GY26_17945Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (126 aa)
GY26_19340Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. (861 aa)
GY26_19795Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
GY26_20465Type IV secretion protein Rhs; Derived by automated computational analysis using gene prediction method: Protein Homology. (604 aa)
Your Current Organism:
Gammaproteobacteria bacterium MFB021
NCBI taxonomy Id: 1492922
Other names: G. bacterium MFB021, bacterium MFB021
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