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ART_0593 ART_0593 ART_0807 ART_0807 leuA leuA ART_0917 ART_0917 leuD leuD leuC leuC ART_1330 ART_1330 leuB leuB ilvC ilvC ART_1369 ART_1369 ART_1370 ART_1370 ilvD ilvD leuA-2 leuA-2 ART_1987 ART_1987 ilvD-2 ilvD-2 ART_2657 ART_2657 ART_2661 ART_2661 ART_2841 ART_2841 ART_2979 ART_2979 ART_2980 ART_2980 ART_3073 ART_3073 ART_3581 ART_3581 ART_3769 ART_3769 ART_3930 ART_3930
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ART_0593Dimethylmenaquinone methyltransferase; COG0684. (204 aa)
ART_0807Threonine dehydratase; COG1171. (310 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (606 aa)
ART_0917Pyruvate decarboxylase; COG0028; Belongs to the TPP enzyme family. (607 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (505 aa)
ART_1330Branched-chain amino acid aminotransferase; COG0115. (370 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (355 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (341 aa)
ART_1369Acetolactate synthase, regulatory subunit; COG0440. (170 aa)
ART_1370Acetolactate synthase, catalytic subunit; COG0028. (629 aa)
ilvDDihydroxy-acid dehydratase; COG0129; Belongs to the IlvD/Edd family. (580 aa)
leuA-2Putative 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (604 aa)
ART_1987Putative oxidoreductase; COG1304. (429 aa)
ilvD-2Dihydroxy-acid dehydratase; COG0129; Belongs to the IlvD/Edd family. (617 aa)
ART_2657Acetolactate synthase, large subunit; COG0028; Belongs to the TPP enzyme family. (538 aa)
ART_2661Demethylmenaquinone methyltransferase; COG0684. (202 aa)
ART_2841Pyruvate dehydrogenase; COG0028; Belongs to the TPP enzyme family. (582 aa)
ART_2979Aminodeoxychorismate lyase; COG0115. (330 aa)
ART_2980Hypothetical protein; COG3247. (202 aa)
ART_3073Hypothetical protein; COG1285. (249 aa)
ART_3581Acetolactate synthase, large subunit; COG0028; Belongs to the TPP enzyme family. (569 aa)
ART_3769Acetolactate synthase, large subunit; COG0028; Belongs to the TPP enzyme family. (557 aa)
ART_3930Threonine dehydratase; COG1171. (412 aa)
Your Current Organism:
Arthrobacter sp. PAMC25486
NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486
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