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ART_2858 ART_2858 ART_2767 ART_2767 ART_2597 ART_2597 ART_2458 ART_2458 ART_2452 ART_2452 ART_2448 ART_2448 ART_2447 ART_2447 ART_2446 ART_2446 ART_2237 ART_2237 pfkA pfkA ART_2078 ART_2078 ART_2077 ART_2077 ART_2018 ART_2018 mdh mdh ART_1899 ART_1899 ART_1897 ART_1897 ART_1873 ART_1873 ART_1754 ART_1754 ART_1753 ART_1753 ART_1752 ART_1752 ART_1740 ART_1740 ART_1732 ART_1732 ART_1731 ART_1731 ART_1724 ART_1724 ART_1540 ART_1540 mqo mqo zwf-2 zwf-2 ART_1148 ART_1148 ART_1136 ART_1136 ART_1048 ART_1048 ART_0882 ART_0882 ART_0881 ART_0881 ART_0880 ART_0880 ART_0876 ART_0876 ART_0875 ART_0875 ART_0873 ART_0873 pgk pgk tpiA tpiA pgl pgl zwf zwf ART_0733 ART_0733 tal tal ART_0731 ART_0731 ART_0693 ART_0693 ART_0647 ART_0647 ART_0605 ART_0605 ART_0448 ART_0448 ART_0403 ART_0403 ART_0402 ART_0402 ART_0394 ART_0394 ART_0348 ART_0348 ART_0347 ART_0347 ART_0344 ART_0344 ART_0343 ART_0343 ART_0339 ART_0339 ART_0338 ART_0338 ART_0337 ART_0337 ART_0335 ART_0335 ART_0302 ART_0302 ART_0291 ART_0291 ART_0281 ART_0281 ART_0260 ART_0260 ART_0251 ART_0251 ART_0230 ART_0230 ART_0229 ART_0229 ART_0214 ART_0214 ART_0874 ART_0874 ART_0028 ART_0028 ART_0026 ART_0026 ART_4224 ART_4224 ART_4223 ART_4223 ART_4181 ART_4181 ART_4168 ART_4168 ART_4022 ART_4022 fumC fumC eno eno ART_3900 ART_3900 ART_3899 ART_3899 ART_3898 ART_3898 ART_3897 ART_3897 ART_3866 ART_3866 ART_3800 ART_3800 ART_3789 ART_3789 ART_3759 ART_3759 sucD sucD sucC sucC ART_3726 ART_3726 ART_3527 ART_3527 ART_3463 ART_3463 ART_3457 ART_3457 ART_3456 ART_3456 ART_3339 ART_3339 ART_3330 ART_3330 ART_3324 ART_3324 gpmA gpmA ppc ppc ART_3158 ART_3158 ART_3157 ART_3157 ldh ldh ART_2955 ART_2955 ART_2859 ART_2859
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ART_2858Pyruvate dehydrogenase E1 component, beta subunit; COG0022. (321 aa)
ART_2767Putative 6-phosphogluconate dehydrogenase; COG1023. (285 aa)
ART_2597Hypothetical protein; COG3383. (86 aa)
ART_2458Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (566 aa)
ART_2452Putative fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
ART_2448Hypothetical protein. (390 aa)
ART_2447Hypothetical protein; COG4262. (637 aa)
ART_2446Putative multicopper oxidase; COG2132. (259 aa)
ART_2237Putative phosphoglycerate/bisphosphoglycerate mutase; COG0406; Belongs to the phosphoglycerate mutase family. (226 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
ART_2078Glycogen debranching enzyme; COG1523; Belongs to the glycosyl hydrolase 13 family. (385 aa)
ART_2077Glycogen debranching enzyme; COG1523. (312 aa)
ART_2018Hypothetical protein. (285 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
ART_18994Fe-4S ferredoxin. (59 aa)
ART_1897Putative citrate synthase; COG0372; Belongs to the citrate synthase family. (427 aa)
ART_1873Hypothetical protein. (262 aa)
ART_1754Putative electron transfer flavoprotein subunit beta; COG2086. (255 aa)
ART_1753Putative electron transfer flavoprotein subunit alpha; COG2025. (325 aa)
ART_1752Hypothetical protein; COG4117. (317 aa)
ART_1740Hypothetical protein; COG1512. (676 aa)
ART_1732Putative electron transfer flavoprotein subunit beta; COG2086. (268 aa)
ART_1731Putative electron transfer flavoprotein subunit alpha; COG2025. (322 aa)
ART_1724Ferredoxin reductase; COG1251. (422 aa)
ART_15402-oxoglutarate decarboxylase; COG0567. (1264 aa)
mqoMalate:quinone oxidoreductase; COG0579. (499 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (506 aa)
ART_1148Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
ART_11366-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
ART_1048Hypothetical protein; COG4243. (211 aa)
ART_0882Cytochrome c oxidase subunit II; COG1622. (293 aa)
ART_0881Cytochrome c oxidase subunit I; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (568 aa)
ART_0880Putative cytochrome c oxidase; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family. (133 aa)
ART_0876Cytochrome b subunit of the bc complex; COG1290. (556 aa)
ART_08752Fe-2S domain-containing protein; COG0723. (342 aa)
ART_0873Cytochrome c oxidase polypeptide III; COG1845. (183 aa)
pgkPhosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. (412 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (271 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (267 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa)
ART_0733Glucose-6-phosphate isomerase; COG0166. (545 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (373 aa)
ART_0731Transketolase; COG0021; Belongs to the transketolase family. (708 aa)
ART_0693ADP-glucose pyrophosphorylase; COG0448; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (425 aa)
ART_0647Aconitate hydratase; COG1048. (934 aa)
ART_0605Hypothetical protein. (246 aa)
ART_0448Succinate dehydrogenase, flavoprotein subunit; COG1053. (579 aa)
ART_0403Hypothetical protein; COG1053. (154 aa)
ART_0402Succinate dehydrogenase, flavoprotein subunit; COG1053. (85 aa)
ART_0394Hypothetical protein; COG4925. (193 aa)
ART_0348Hypothetical protein; COG0716. (179 aa)
ART_0347Ferredoxin reductase; COG1251. (437 aa)
ART_0344Hypothetical protein; COG1053. (648 aa)
ART_0343Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; COG0479. (249 aa)
ART_0339Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (341 aa)
ART_0338Dihydrolipoyllysine-residue acetyltransferase; COG0508. (421 aa)
ART_0337Transketolase; COG0021. (632 aa)
ART_0335Molybdopterin-binding oxidoreductase; COG2041. (593 aa)
ART_0302Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (461 aa)
ART_0291Hypothetical protein. (231 aa)
ART_0281Ribulose-5-phosphate 3-epimerase; COG0036; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
ART_0260Hypothetical protein; COG2146. (150 aa)
ART_0251Aconitase; COG1048. (941 aa)
ART_0230Cytochrome d ubiquinol oxidase subunit II; COG1294. (354 aa)
ART_0229Cytochrome d ubiquinol oxidase subunit I; COG1271. (528 aa)
ART_02142-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; COG0508. (591 aa)
ART_0874Cytochrome C heme-binding subunit; COG2010. (262 aa)
ART_00282-methylcitrate dehydratase; COG2079. (506 aa)
ART_00262-methylcitrate synthase; COG0372; Belongs to the citrate synthase family. (379 aa)
ART_4224Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; COG0508. (451 aa)
ART_4223Pyruvate dehydrogenase E1 component, beta subunit; COG0022. (336 aa)
ART_4181Hypothetical protein; COG2706. (374 aa)
ART_4168Putative phosphoglycerate mutase; COG0406; Belongs to the phosphoglycerate mutase family. (225 aa)
ART_4022Hydroxyglutarate oxidase; COG0579. (398 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (476 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
ART_3900Succinate dehydrogenase cytochrome, b-556 subunit; COG2009. (111 aa)
ART_3899Succinate dehydrogenase hydrophobic membrane anchor protein; COG2142. (155 aa)
ART_3898Succinate dehydrogenase, flavoprotein subunit; COG1053. (599 aa)
ART_3897Succinate dehydrogenase iron-sulfur protein; COG0479; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (263 aa)
ART_3866Isocitrate dehydrogenase; COG2838; Belongs to the monomeric-type IDH family. (739 aa)
ART_3800Triosephosphate isomerase; COG0149. (267 aa)
ART_3789Aspartate ammonia-lyase; COG1027. (483 aa)
ART_3759Hypothetical protein; COG0508. (96 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
ART_3726Putative oxidoreductase; COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (780 aa)
ART_3527Hypothetical protein. (133 aa)
ART_3463Thiosulfate reductase cytochrome subunit beta (membrane anchoring protein); COG4117. (317 aa)
ART_3457Hypothetical protein; COG2086. (262 aa)
ART_3456Hypothetical protein; COG2025. (334 aa)
ART_3339Glycolate oxidase, subunit GlcD; COG0277. (457 aa)
ART_3330Hypothetical protein; COG3281. (490 aa)
ART_3324Isoamylase; COG1523; Belongs to the glycosyl hydrolase 13 family. (720 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (939 aa)
ART_3158Isocitrate lyase; COG2224. (440 aa)
ART_3157Malate synthase A; COG2225; Belongs to the malate synthase family. (549 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)
ART_2955Multisubunit Na+/H+ antiporter, MnhD subunit; COG0651. (542 aa)
ART_2859Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; COG0508. (488 aa)
Your Current Organism:
Arthrobacter sp. PAMC25486
NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486
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