(34 nodes) Lipid catabolic process network (Arthrobacter sp. PAMC25486)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	ART_0027	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (309 aa)
	ART_0077	Hypothetical protein; COG1960. (598 aa)
	ART_0261	3-hydroxyacyl-CoA dehydrogenase; COG1250. (703 aa)
	ART_0262	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
	ART_0522	Hypothetical protein; COG1752. (309 aa)
	ART_0683	acyl-CoA dehydrogenase; COG1960. (383 aa)
	ART_0689	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (452 aa)
	ART_0691	acyl-CoA oxidase; COG1960. (691 aa)
	ART_0717	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
	ART_0888	Hypothetical protein; COG3573. (557 aa)
	ART_1227	acyl-CoA dehydrogenase domain-containing protein; COG1960. (406 aa)
	ART_1710	Hypothetical protein; COG2755. (293 aa)
	ART_1751	Hypothetical protein; COG1960. (378 aa)
	ART_1760	3-hydroxyacyl-CoA dehydrogenase; COG1250. (726 aa)
	ART_1761	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
	ART_1762	acyl-CoA dehydrogenase; COG1960. (385 aa)
	ART_1769	acyl-CoA dehydrogenase; COG1960. (390 aa)
	ART_1772	Hypothetical protein. (568 aa)
	ART_1957	Hypothetical protein; COG3247. (620 aa)
	ART_2133	Lysophospholipase-like family protein; COG1752. (332 aa)
	ART_2137	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	ART_2312	phenylacetate-CoA oxygenase/reductase subunit PaaK; COG1018. (402 aa)
	ART_2325	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (408 aa)
	ART_2886	Esterase A; COG1680. (379 aa)
	ART_3165	Hypothetical protein; COG1960. (441 aa)
	ART_3221	acyl-CoA dehydrogenase domain-containing protein; COG1960. (404 aa)
	ART_3274	Hypothetical protein; COG1075. (252 aa)
	ART_3450	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
	ART_3458	Fumarate reductase flavoprotein subunit; COG1053. (471 aa)
	ART_3483	Putative acyl-CoA dehydrogenase; COG1960. (398 aa)
	ART_3843	Putative acyl-CoA dehydrogenase; COG1960. (558 aa)
	ART_4206	Putative acyl-CoA dehydrogenase; COG1960. (396 aa)
	ART_4230	butyryl-CoA dehydrogenase; COG1960. (387 aa)
	ART_4262	Hypothetical protein; COG1960. (385 aa)

Your Current Organism:

Arthrobacter sp. PAMC25486

NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ART_0027	ART_0689	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.835
ART_0027	ART_0717	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.835
ART_0027	ART_1761	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.835
ART_0027	ART_2137	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.835
ART_0027	ART_3450	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.835
ART_0027	ART_3458	Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate.	Fumarate reductase flavoprotein subunit; COG1053.	0.800
ART_0077	ART_0261	Hypothetical protein; COG1960.	3-hydroxyacyl-CoA dehydrogenase; COG1250.	0.809
ART_0077	ART_0262	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.702
ART_0077	ART_0689	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.702
ART_0077	ART_0717	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.702
ART_0077	ART_1760	Hypothetical protein; COG1960.	3-hydroxyacyl-CoA dehydrogenase; COG1250.	0.917
ART_0077	ART_1761	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.516
ART_0077	ART_2137	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.429
ART_0077	ART_2325	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.702
ART_0077	ART_3450	Hypothetical protein; COG1960.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.427
ART_0261	ART_0077	3-hydroxyacyl-CoA dehydrogenase; COG1250.	Hypothetical protein; COG1960.	0.809
ART_0261	ART_0262	3-hydroxyacyl-CoA dehydrogenase; COG1250.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.998
ART_0261	ART_0683	3-hydroxyacyl-CoA dehydrogenase; COG1250.	acyl-CoA dehydrogenase; COG1960.	0.809
ART_0261	ART_0689	3-hydroxyacyl-CoA dehydrogenase; COG1250.	acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family.	0.978
ART_0261	ART_0691	3-hydroxyacyl-CoA dehydrogenase; COG1250.	acyl-CoA oxidase; COG1960.	0.838