STRINGSTRING
ART_4342 ART_4342 nadK nadK ART_0020 ART_0020 ART_0037 ART_0037 ART_0045 ART_0045 cmk cmk ART_0071 ART_0071 ART_0072 ART_0072 ART_0086 ART_0086 ART_0094 ART_0094 ART_0099 ART_0099 ART_0101 ART_0101 ART_0134 ART_0134 ART_0210 ART_0210 ART_0214 ART_0214 ART_0252 ART_0252 ART_0302 ART_0302 ART_0338 ART_0338 ART_0339 ART_0339 ART_0363 ART_0363 ART_0368 ART_0368 ART_0460 ART_0460 ART_0559 ART_0559 ART_0612 ART_0612 ART_0618 ART_0618 ART_0644 ART_0644 ART_0733 ART_0733 tpiA tpiA pgk pgk ART_0748 ART_0748 ART_0754 ART_0754 coaE coaE ART_0818 ART_0818 ART_0842 ART_0842 glpK glpK gmk gmk aroK aroK ART_0981 ART_0981 proB proB ART_1045 ART_1045 ndk ndk ART_1105 ART_1105 ART_1148 ART_1148 thiL thiL ART_1232 ART_1232 ART_1325 ART_1325 ART_1334 ART_1334 ART_1360 ART_1360 ART_1391 ART_1391 ART_1431 ART_1431 thrB thrB ART_1517 ART_1517 ART_1524 ART_1524 ART_1689 ART_1689 ART_1703 ART_1703 ART_1725 ART_1725 ART_1789 ART_1789 ART_1863 ART_1863 ART_1911 ART_1911 ART_1950 ART_1950 araB araB ART_2060 ART_2060 coaA coaA adk adk ART_2150 ART_2150 pfkA pfkA ppk ppk argB argB ART_2196 ART_2196 ART_2208 ART_2208 ART_2215 ART_2215 ART_2219 ART_2219 ART_2236 ART_2236 ART_2237 ART_2237 ART_2306 ART_2306 ackA ackA ART_2335 ART_2335 ART_2386 ART_2386 ART_2400 ART_2400 ART_2441 ART_2441 ART_2452 ART_2452 ART_2457 ART_2457 ART_2459 ART_2459 ART_2461 ART_2461 ART_2519 ART_2519 ART_2521 ART_2521 ART_2526 ART_2526 ART_2555 ART_2555 ART_2556 ART_2556 rbsK rbsK ART_2572 ART_2572 ART_2574 ART_2574 ART_2587 ART_2587 ART_2612 ART_2612 ART_2616 ART_2616 ART_2622 ART_2622 ART_2648 ART_2648 ART_2711 ART_2711 ART_2721 ART_2721 ART_2726 ART_2726 ART_2732 ART_2732 ART_2742 ART_2742 ART_2747 ART_2747 ART_2749 ART_2749 ART_2782 ART_2782 ART_2790 ART_2790 ART_2791 ART_2791 ART_2817 ART_2817 xylB xylB ART_2858 ART_2858 ART_2859 ART_2859 ldh ldh ART_3002 ART_3002 ART_3013 ART_3013 ART_3102 ART_3102 ART_3132 ART_3132 ART_3248 ART_3248 ART_3266 ART_3266 tmk tmk gpmA gpmA ART_3316 ART_3316 ART_3330 ART_3330 glgB glgB ART_3340 ART_3340 ART_3399 ART_3399 ART_3441 ART_3441 ART_3584 ART_3584 ART_3586 ART_3586 ART_3666 ART_3666 ART_3669 ART_3669 ART_3670 ART_3670 ART_3693 ART_3693 ART_3738 ART_3738 ART_3772 ART_3772 ART_3795 ART_3795 ART_3800 ART_3800 ART_3804 ART_3804 ART_3819 ART_3819 xylB-2 xylB-2 ART_3889 ART_3889 eno eno galK galK ART_3969 ART_3969 ART_3979 ART_3979 ART_3982 ART_3982 ispE ispE prs prs ART_4107 ART_4107 ART_4116 ART_4116 ART_4118 ART_4118 ART_4119 ART_4119 ART_4145 ART_4145 ART_4157 ART_4157 ART_4165 ART_4165 ART_4168 ART_4168 pyrH pyrH ART_4218 ART_4218 ART_4223 ART_4223 ART_4224 ART_4224 ART_4252 ART_4252 ART_4268 ART_4268
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ART_4342Hypothetical protein. (265 aa)
nadKNAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (358 aa)
ART_00202-keto-3-deoxygluconate kinase; COG0524. (347 aa)
ART_0037Hypothetical protein; COG3173. (311 aa)
ART_0045Histidine kinase; COG3290. (330 aa)
cmkCytidylate kinase; COG0283. (252 aa)
ART_0071Hypothetical protein. (270 aa)
ART_0072Histidine kinase; COG4585. (431 aa)
ART_0086Hypothetical protein; COG1716. (160 aa)
ART_0094Glucokinase; COG1940. (348 aa)
ART_0099Hypothetical protein; COG0515. (694 aa)
ART_0101Hypothetical protein. (117 aa)
ART_0134Polyphosphate ATP-glucomannokinase; COG1940. (264 aa)
ART_0210Hypothetical protein; COG0515. (595 aa)
ART_02142-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; COG0508. (591 aa)
ART_0252Hypothetical protein. (218 aa)
ART_0302Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (461 aa)
ART_0338Dihydrolipoyllysine-residue acetyltransferase; COG0508. (421 aa)
ART_0339Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (341 aa)
ART_0363Putative signal transduction histidine kinase; COG4585. (573 aa)
ART_0368ABC-1 domain protein; COG0661. (547 aa)
ART_0460Histidine kinase; COG4585. (422 aa)
ART_0559Hypothetical protein. (108 aa)
ART_0612Histidine kinase; COG4585. (255 aa)
ART_0618Hypothetical protein; COG2320. (251 aa)
ART_0644Hypothetical protein; COG2334. (248 aa)
ART_0733Glucose-6-phosphate isomerase; COG0166. (545 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (271 aa)
pgkPhosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. (412 aa)
ART_0748HAD superfamily protein; COG0546. (240 aa)
ART_0754Hypothetical protein; COG3550. (283 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (307 aa)
ART_0818Signal transduction histidine kinase; COG4585. (284 aa)
ART_0842Hypothetical protein; COG1940. (388 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (504 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (204 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (192 aa)
ART_0981Glutamate-cysteine ligase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (780 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (383 aa)
ART_1045Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. (529 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa)
ART_1105Hypothetical protein; COG4585. (670 aa)
ART_1148Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (338 aa)
ART_1232Hypothetical protein; COG0661. (569 aa)
ART_1325Hypothetical protein; COG4585. (437 aa)
ART_1334Histidine kinase; COG4585. (467 aa)
ART_1360Glucokinase; COG1940. (292 aa)
ART_1391Histidine kinase; COG0642. (492 aa)
ART_1431Hypothetical protein. (515 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (322 aa)
ART_1517Thermoresistant glucokinase family carbohydrate kinase; COG3265. (179 aa)
ART_1524Thermoresistant glucokinase family carbohydrate kinase; COG3265. (173 aa)
ART_1689Signal transduction histidine kinase; COG3920. (492 aa)
ART_1703Two component system histidine kinase; COG0642. (627 aa)
ART_1725Putative dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (316 aa)
ART_1789Aminoglycoside phosphotransferase; COG3173. (442 aa)
ART_1863ABC-1 domain protein; COG0661. (675 aa)
ART_1911Histidine kinase; COG4585. (373 aa)
ART_1950Hypothetical protein; COG2971. (307 aa)
araBRibulokinase; COG1069. (560 aa)
ART_2060Histidine kinase; COG0642. (325 aa)
coaAPantothenate kinase; COG1072. (322 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (191 aa)
ART_2150Histidine kinase; COG4585. (424 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)
ppkPolyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (747 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (298 aa)
ART_2196Osmosensitive K+ channel signal transduction histidine kinase; COG2205. (845 aa)
ART_2208Putative adenylate kinase; COG0563. (203 aa)
ART_2215Carbohydrate kinase; COG1070; Belongs to the FGGY kinase family. (493 aa)
ART_2219Dihydroxyacetone kinase; COG2376. (569 aa)
ART_2236Hypothetical protein; COG4585. (424 aa)
ART_2237Putative phosphoglycerate/bisphosphoglycerate mutase; COG0406; Belongs to the phosphoglycerate mutase family. (226 aa)
ART_2306Hypothetical protein; COG1597. (301 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (377 aa)
ART_2335RIO-type Ser/Thr protein kinase; COG1718. (321 aa)
ART_2386Hypothetical protein; COG3550. (420 aa)
ART_2400Aspartate kinase; COG0527; Belongs to the aspartokinase family. (428 aa)
ART_2441Hypothetical protein. (295 aa)
ART_2452Putative fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
ART_2457Thymidine kinase; COG1435. (206 aa)
ART_2459Thymidine kinase; COG1435. (208 aa)
ART_2461Hypothetical protein; COG0524. (323 aa)
ART_25191-phosphofructokinase; COG1105; Belongs to the carbohydrate kinase PfkB family. (320 aa)
ART_2521Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (570 aa)
ART_2526Phosphomethylpyrimidine kinase; COG0351. (277 aa)
ART_2555Dihydroxyacetone kinase; COG2376. (214 aa)
ART_2556Dihydroxyacetone kinase substrate-binding subunit; COG2376. (340 aa)
rbsKPfkB domain-containing protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (310 aa)
ART_25722-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COG0801. (174 aa)
ART_2574Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (328 aa)
ART_2587Diacylglycerol kinase; COG1597. (356 aa)
ART_2612Glycerate kinase; COG1929; Belongs to the glycerate kinase type-1 family. (371 aa)
ART_2616Fructokinase; COG0524. (313 aa)
ART_2622Histidine kinase; COG4585. (408 aa)
ART_2648Hypothetical protein; COG1940. (392 aa)
ART_2711Histidine kinase; COG4585. (427 aa)
ART_2721Hypothetical protein; COG4585. (477 aa)
ART_2726Histidine kinase; COG4585. (436 aa)
ART_2732Putative two-component histidine kinase; COG4585. (430 aa)
ART_2742Hypothetical protein. (457 aa)
ART_2747Transposase of ISAar22, IS481 family. (59 aa)
ART_2749Transposase of ISAar22, IS481 family. (91 aa)
ART_2782Hypothetical protein; COG2320. (197 aa)
ART_2790Non-spific serine/threonine protein kinase; COG0515. (643 aa)
ART_2791Serine/threonine protein kinase; COG0515. (594 aa)
ART_2817Hypothetical protein; COG2971. (347 aa)
xylBD-xylulose kinase; COG1070. (473 aa)
ART_2858Pyruvate dehydrogenase E1 component, beta subunit; COG0022. (321 aa)
ART_2859Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; COG0508. (488 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)
ART_3002Two-component system, sensor kinase; COG4585. (460 aa)
ART_3013Histidine kinase; COG4585. (437 aa)
ART_3102Carbohydrate kinase; COG1070. (495 aa)
ART_3132Sensor histidine kinase; COG2205. (310 aa)
ART_3248Hypothetical protein; COG0642. (522 aa)
ART_3266Glucokinase; COG1940. (310 aa)
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (235 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
ART_3316Histidine kinase; COG5002. (410 aa)
ART_3330Hypothetical protein; COG3281. (490 aa)
glgBGlycogen branching protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (732 aa)
ART_3340Hypothetical protein. (455 aa)
ART_3399Hypothetical protein; COG1072. (236 aa)
ART_3441Hypothetical protein; COG0524. (305 aa)
ART_3584Hypothetical protein; COG4585. (429 aa)
ART_3586ABC-1 domain protein. (235 aa)
ART_3666Hypothetical protein; COG4585. (705 aa)
ART_3669Hypothetical protein. (446 aa)
ART_3670Hypothetical protein; COG4585. (232 aa)
ART_3693Hypothetical protein; COG0642. (543 aa)
ART_3738Hypothetical protein; COG0061. (296 aa)
ART_3772Hypothetical protein. (206 aa)
ART_3795Dihydroxyacetone kinase; COG2376. (580 aa)
ART_3800Triosephosphate isomerase; COG0149. (267 aa)
ART_3804Hypothetical protein; COG3395. (488 aa)
ART_3819Hypothetical protein; COG1940. (421 aa)
xylB-2Putative xylulokinase; COG1070. (490 aa)
ART_3889Hypothetical protein; COG4585. (441 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (386 aa)
ART_3969Hypothetical protein. (59 aa)
ART_3979Hypothetical protein; COG0489. (541 aa)
ART_3982Hypothetical protein. (365 aa)
ispE4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (335 aa)
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa)
ART_4107Serine/threonine protein kinase; COG0515. (588 aa)
ART_4116Histidine kinase; COG4585. (412 aa)
ART_4118ROK family protein; COG1940. (118 aa)
ART_4119Hypothetical protein; COG1940. (140 aa)
ART_4145Hypothetical protein; COG2320. (325 aa)
ART_4157Hypothetical protein; COG3173. (313 aa)
ART_4165Sugar kinase; COG1105. (320 aa)
ART_4168Putative phosphoglycerate mutase; COG0406; Belongs to the phosphoglycerate mutase family. (225 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (259 aa)
ART_4218Signal transduction histidine kinase; COG3275. (410 aa)
ART_4223Pyruvate dehydrogenase E1 component, beta subunit; COG0022. (336 aa)
ART_4224Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; COG0508. (451 aa)
ART_4252Hypothetical protein; COG3570. (359 aa)
ART_4268FMN adenylyltransferase; COG0196; Belongs to the ribF family. (313 aa)
Your Current Organism:
Arthrobacter sp. PAMC25486
NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486
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