STRINGSTRING
ART_0028 ART_0028 ART_0251 ART_0251 trpB trpB trpA trpA ART_0647 ART_0647 ART_0790 ART_0790 aroB aroB aroC aroC ART_0992 ART_0992 ART_1068 ART_1068 mutM mutM hutU hutU leuD leuD leuC leuC ilvD ilvD ART_1462 ART_1462 ART_1669 ART_1669 ART_1763 ART_1763 ART_1803 ART_1803 ART_1804 ART_1804 ART_1819 ART_1819 nnrE nnrE ART_2179 ART_2179 menC menC ART_2311 ART_2311 ilvD-2 ilvD-2 pheA pheA ART_2604 ART_2604 aroQ aroQ ART_3191 ART_3191 ART_3241 ART_3241 ART_3267 ART_3267 ART_3284 ART_3284 ART_3484 ART_3484 ART_3500 ART_3500 ART_3678 ART_3678 murQ murQ ART_3879 ART_3879 eno eno fumC fumC ART_3954 ART_3954 ART_4058 ART_4058 ART_4233 ART_4233 dapA dapA hisB hisB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ART_00282-methylcitrate dehydratase; COG2079. (506 aa)
ART_0251Aconitase; COG1048. (941 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (483 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (280 aa)
ART_0647Aconitate hydratase; COG1048. (934 aa)
ART_0790Hypothetical protein. (419 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (366 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
ART_0992Hypothetical protein; COG0329; Belongs to the DapA family. (301 aa)
ART_1068Putative DNA glycosylase; COG0266; Belongs to the FPG family. (328 aa)
mutMformamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (309 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (559 aa)
leuD3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (199 aa)
leuCIsopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (505 aa)
ilvDDihydroxy-acid dehydratase; COG0129; Belongs to the IlvD/Edd family. (580 aa)
ART_1462Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (367 aa)
ART_1669dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (332 aa)
ART_1763Putative enoyl-CoA hydratase; COG1024; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
ART_1803Porphobilinogen synthase; COG0113; Belongs to the ALAD family. (326 aa)
ART_1804Uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (281 aa)
ART_18194a-hydroxytetrahydrobiopterin dehydratase; COG2154. (218 aa)
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (547 aa)
ART_2179Hypothetical protein; COG2030; Belongs to the UPF0336 family. (149 aa)
menCO-succinylbenzoate synthase; Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB). (336 aa)
ART_2311Hypothetical protein; COG1024. (260 aa)
ilvD-2Dihydroxy-acid dehydratase; COG0129; Belongs to the IlvD/Edd family. (617 aa)
pheAPrephenate dehydratase; COG0077. (312 aa)
ART_2604Dihydrodipicolinate synthase; COG0329; Belongs to the DapA family. (301 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (152 aa)
ART_31912-oxo-hepta-3-ene-1,7-dioic acid hydratase; COG3971. (261 aa)
ART_3241Putative endonuclease VIII/DNA glycosylase; COG0266. (269 aa)
ART_3267Dihydrodipicolinate synthase; COG0329; Belongs to the DapA family. (309 aa)
ART_3284Mandelate racemase/muconate lactonizing enzyme; COG4948; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (445 aa)
ART_3484Hypothetical protein; COG2030. (164 aa)
ART_3500Hypothetical protein; COG2030. (161 aa)
ART_3678Hypothetical protein; COG1024. (263 aa)
murQHypothetical protein; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (324 aa)
ART_3879Hypothetical protein; COG0663. (172 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (476 aa)
ART_3954Carbonic anhydrase; COG0288. (219 aa)
ART_4058Putative uroporphyrinogen-III synthase; COG1587. (379 aa)
ART_4233Dehydratase; COG2030. (167 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
hisBImidazole glycerol phosphate dehydratase; COG0131. (206 aa)
Your Current Organism:
Arthrobacter sp. PAMC25486
NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486
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