STRINGSTRING
hisA hisA ART_0060 ART_0060 ART_0126 ART_0126 ART_0226 ART_0226 ART_0235 ART_0235 ART_0281 ART_0281 ART_0663 ART_0663 ART_0664 ART_0664 ART_0733 ART_0733 tpiA tpiA ART_0763 ART_0763 trpF trpF ART_0978 ART_0978 tig tig ART_1069 ART_1069 ART_1256 ART_1256 ART_1274 ART_1274 ART_1277 ART_1277 ART_1278 ART_1278 ART_1286 ART_1286 ART_1351 ART_1351 murI murI nagB nagB ART_1527 ART_1527 ART_1657 ART_1657 ART_1667 ART_1667 ART_1668 ART_1668 ART_1676 ART_1676 ART_1684 ART_1684 ART_1712 ART_1712 hemL hemL araA araA ART_1992 ART_1992 ART_1995 ART_1995 ART_1996 ART_1996 groL groL ART_2067 ART_2067 ART_2074 ART_2074 nnrE nnrE glmM glmM truA truA ART_2159 ART_2159 ART_2220 ART_2220 ART_2282 ART_2282 ART_2294 ART_2294 ART_2347 ART_2347 ART_2434 ART_2434 pheA pheA ART_2592 ART_2592 ART_2603 ART_2603 ART_2606 ART_2606 ART_2623 ART_2623 gyrB gyrB gyrA gyrA ART_2777 ART_2777 topA topA ART_3099 ART_3099 ART_3100 ART_3100 ART_3141 ART_3141 ART_3156 ART_3156 ART_3237 ART_3237 nanE nanE ART_3279 ART_3279 ART_3283 ART_3283 ART_3286 ART_3286 gpmA gpmA ART_3329 ART_3329 ART_3338 ART_3338 ART_3345 ART_3345 ART_3401 ART_3401 ART_3497 ART_3497 ART_3541 ART_3541 ART_3631 ART_3631 ART_3632 ART_3632 groL-2 groL-2 ART_3796 ART_3796 ART_3800 ART_3800 idi idi xylA xylA ART_3823 ART_3823 ART_3850 ART_3850 ART_3928 ART_3928 ART_3958 ART_3958 purE purE ART_4010 ART_4010 ART_4063 ART_4063 ART_4168 ART_4168 truB truB dapF dapF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisAPhosphoribosyl isomerase A; COG0106. (244 aa)
ART_0060RNA pseudouridine synthase; COG1187; Belongs to the pseudouridine synthase RsuA family. (389 aa)
ART_0126RNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (307 aa)
ART_0226DNA topoisomerase IV subunit B; COG0187. (703 aa)
ART_0235DNA topoisomerase IV subunit A; COG0188. (880 aa)
ART_0281Ribulose-5-phosphate 3-epimerase; COG0036; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
ART_0663Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG0545. (131 aa)
ART_0664Peptidyl-prolyl cis-trans isomerase, FKBP-type; COG0545. (289 aa)
ART_0733Glucose-6-phosphate isomerase; COG0166. (545 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (271 aa)
ART_0763Hypothetical protein. (167 aa)
trpFPhosphoribosylanthranilate isomerase; COG0135; Belongs to the TrpF family. (204 aa)
ART_0978Cyclophilin type peptidyl-prolyl cis-trans isomerase; COG0652. (259 aa)
tigHypothetical protein; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (454 aa)
ART_1069Ribose 5-phosphate isomerase; COG0698. (157 aa)
ART_1256UDP-N-acetylglucosamine 2-epimerase; COG0381; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (388 aa)
ART_1274Hypothetical protein. (424 aa)
ART_1277Hypothetical protein; COG0363. (249 aa)
ART_1278Hypothetical protein; COG2942. (434 aa)
ART_1286UDP-N-acetylglucosamine 2-epimerase; COG0381; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (380 aa)
ART_1351Hypothetical protein; COG3718. (264 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (346 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (259 aa)
ART_1527Glucuronate isomerase; COG1904. (485 aa)
ART_1657UDP-N-acetylglucosamine 2-epimerase; COG0381; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (359 aa)
ART_1667UDP-glucose 4-epimerase; COG1087; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
ART_1668dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (469 aa)
ART_1676NAD-dependent epimerase/dehydratase; COG0451. (362 aa)
ART_1684UDP-galactopyranose mutase; COG0562. (394 aa)
ART_1712Putative chorismate mutase; COG1605. (157 aa)
hemLGlutamate-1-semialdehyde aminotransferase; COG0001. (435 aa)
araAPutative L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose. (506 aa)
ART_1992L-ribulose-5-phosphate 4-epimerase; COG0235. (239 aa)
ART_1995Hypothetical protein. (62 aa)
ART_1996Hypothetical protein; COG2017. (316 aa)
groLMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (535 aa)
ART_2067Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (412 aa)
ART_2074Inositol-3-phosphate synthase; COG1260. (359 aa)
nnrEHypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (547 aa)
glmMPhosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (436 aa)
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (299 aa)
ART_2159Hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (200 aa)
ART_2220Ribose 5-phosphate isomerase; COG0698. (152 aa)
ART_2282Hypothetical protein; COG1651. (396 aa)
ART_2294Isochorismate synthase; COG1169. (452 aa)
ART_2347Hypothetical protein; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (227 aa)
ART_2434Hypothetical protein; COG1794. (78 aa)
pheAPrephenate dehydratase; COG0077. (312 aa)
ART_2592Phosphoglucomutase; COG0033. (547 aa)
ART_2603Hypothetical protein; COG3938; Belongs to the proline racemase family. (333 aa)
ART_2606Proline racemase; COG3938; Belongs to the proline racemase family. (325 aa)
ART_2623Hypothetical protein; COG3938; Belongs to the proline racemase family. (336 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (689 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (855 aa)
ART_2777Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (180 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (930 aa)
ART_3099Hypothetical protein; COG3254. (111 aa)
ART_3100Putative L-rhamnose isomerase; COG4952. (388 aa)
ART_3141Xylose isomerase domain-containing protein; COG1082. (333 aa)
ART_3156Hypothetical protein; COG2761. (237 aa)
ART_3237Ribosomal pseudouridine synthase; COG0564. (309 aa)
nanEN-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). (228 aa)
ART_3279Phosphomannomutase; COG1109. (472 aa)
ART_32832-hydroxyhepta-2,4-diene-1,7-dioate isomerase; COG0179. (293 aa)
ART_3286Hypothetical protein; COG3254. (104 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa)
ART_3329Trehalose synthase; COG0366. (595 aa)
ART_3338Alpha-amylase; COG0366. (622 aa)
ART_3345Hypothetical protein; COG1651. (300 aa)
ART_3401Hypothetical protein; COG2942. (402 aa)
ART_3497Hypothetical protein; COG0179. (273 aa)
ART_3541Hypothetical protein; COG3569. (313 aa)
ART_3631Hypothetical protein. (118 aa)
ART_3632C50 carotenoid epsilon cyclase. (119 aa)
groL-2Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (542 aa)
ART_3796Ribose 5-phosphate isomerase; COG0698. (162 aa)
ART_3800Triosephosphate isomerase; COG0149. (267 aa)
idiIsopentenyl-diphosphate delta-isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). (182 aa)
xylAXylose isomerase; COG2115; Belongs to the xylose isomerase family. (396 aa)
ART_3823Putative aldose 1-epimerase; COG2017. (315 aa)
ART_3850Hypothetical protein; COG1651. (281 aa)
ART_3928Aldose 1-epimerase; COG2017. (309 aa)
ART_3958Mannose-6-phosphate isomerase; COG1482. (419 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (190 aa)
ART_4010UDP-glucose 4-epimerase; COG0451. (336 aa)
ART_4063Phosphoglucomutase; COG1109. (624 aa)
ART_4168Putative phosphoglycerate mutase; COG0406; Belongs to the phosphoglycerate mutase family. (225 aa)
truBtRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (300 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (311 aa)
Your Current Organism:
Arthrobacter sp. PAMC25486
NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486
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