node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ART_0890 | dxs | ART_0890 | ART_0256 | Undecaprenyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.551 |
ART_1045 | ART_1821 | ART_1045 | ART_1821 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | Thiamine biosynthesis protein ThiS; COG2104. | 0.956 |
ART_1045 | ART_2526 | ART_1045 | ART_2526 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | Phosphomethylpyrimidine kinase; COG0351. | 0.896 |
ART_1045 | dxs | ART_1045 | ART_0256 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | 0.419 |
ART_1045 | thiE | ART_1045 | ART_1823 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.999 |
ART_1045 | thiG | ART_1045 | ART_1820 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.987 |
ART_1045 | thiL | ART_1045 | ART_1210 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.596 |
ART_1819 | ART_1821 | ART_1819 | ART_1821 | 4a-hydroxytetrahydrobiopterin dehydratase; COG2154. | Thiamine biosynthesis protein ThiS; COG2104. | 0.548 |
ART_1819 | thiE | ART_1819 | ART_1823 | 4a-hydroxytetrahydrobiopterin dehydratase; COG2154. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.410 |
ART_1819 | thiG | ART_1819 | ART_1820 | 4a-hydroxytetrahydrobiopterin dehydratase; COG2154. | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.723 |
ART_1821 | ART_1045 | ART_1821 | ART_1045 | Thiamine biosynthesis protein ThiS; COG2104. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | 0.956 |
ART_1821 | ART_1819 | ART_1821 | ART_1819 | Thiamine biosynthesis protein ThiS; COG2104. | 4a-hydroxytetrahydrobiopterin dehydratase; COG2154. | 0.548 |
ART_1821 | ART_2526 | ART_1821 | ART_2526 | Thiamine biosynthesis protein ThiS; COG2104. | Phosphomethylpyrimidine kinase; COG0351. | 0.773 |
ART_1821 | thiE | ART_1821 | ART_1823 | Thiamine biosynthesis protein ThiS; COG2104. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.954 |
ART_1821 | thiG | ART_1821 | ART_1820 | Thiamine biosynthesis protein ThiS; COG2104. | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.997 |
ART_2526 | ART_1045 | ART_2526 | ART_1045 | Phosphomethylpyrimidine kinase; COG0351. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase multifunctional protein; COG0351. | 0.896 |
ART_2526 | ART_1821 | ART_2526 | ART_1821 | Phosphomethylpyrimidine kinase; COG0351. | Thiamine biosynthesis protein ThiS; COG2104. | 0.773 |
ART_2526 | thiE | ART_2526 | ART_1823 | Phosphomethylpyrimidine kinase; COG0351. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.995 |
ART_2526 | thiG | ART_2526 | ART_1820 | Phosphomethylpyrimidine kinase; COG0351. | Thiazole biosynthesis protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.896 |
ART_2526 | thiL | ART_2526 | ART_1210 | Phosphomethylpyrimidine kinase; COG0351. | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.555 |