(12 nodes) Streptomycin biosynthesis network (Arthrobacter sp. PAMC25486)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ART_0094	Glucokinase; COG1940. (348 aa)
	ART_1205	Hypothetical protein; COG0673. (339 aa)
	ART_1360	Glucokinase; COG1940. (292 aa)
	ART_1668	dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (469 aa)
	ART_1669	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (332 aa)
	ART_1679	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (287 aa)
	ART_2074	Inositol-3-phosphate synthase; COG1260. (359 aa)
	ART_2592	Phosphoglucomutase; COG0033. (547 aa)
	ART_3266	Glucokinase; COG1940. (310 aa)
	ART_3744	Hypothetical protein; COG0483. (292 aa)
	ART_4112	Inositol-1-monophosphatase; COG0483. (280 aa)
	ART_4164	Hypothetical protein; COG1940. (348 aa)

Your Current Organism:

Arthrobacter sp. PAMC25486

NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
ART_0094	ART_2074	Glucokinase; COG1940.	Inositol-3-phosphate synthase; COG1260.	0.901
ART_0094	ART_2592	Glucokinase; COG1940.	Phosphoglucomutase; COG0033.	0.915
ART_1205	ART_1669	Hypothetical protein; COG0673.	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.464
ART_1205	ART_3744	Hypothetical protein; COG0673.	Hypothetical protein; COG0483.	0.905
ART_1205	ART_4112	Hypothetical protein; COG0673.	Inositol-1-monophosphatase; COG0483.	0.905
ART_1360	ART_2074	Glucokinase; COG1940.	Inositol-3-phosphate synthase; COG1260.	0.901
ART_1360	ART_2592	Glucokinase; COG1940.	Phosphoglucomutase; COG0033.	0.915
ART_1668	ART_1669	dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.999
ART_1668	ART_1679	dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.999
ART_1669	ART_1205	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	Hypothetical protein; COG0673.	0.464
ART_1669	ART_1668	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.	0.999
ART_1669	ART_1679	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	0.999
ART_1679	ART_1668	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	dTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.	0.999
ART_1679	ART_1669	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	dTDP-glucose 4,6-dehydratase; COG1088; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.	0.999
ART_1679	ART_2592	Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.	Phosphoglucomutase; COG0033.	0.915
ART_2074	ART_0094	Inositol-3-phosphate synthase; COG1260.	Glucokinase; COG1940.	0.901
ART_2074	ART_1360	Inositol-3-phosphate synthase; COG1260.	Glucokinase; COG1940.	0.901
ART_2074	ART_2592	Inositol-3-phosphate synthase; COG1260.	Phosphoglucomutase; COG0033.	0.923
ART_2074	ART_3266	Inositol-3-phosphate synthase; COG1260.	Glucokinase; COG1940.	0.901
ART_2074	ART_3744	Inositol-3-phosphate synthase; COG1260.	Hypothetical protein; COG0483.	0.937