STRINGSTRING
ART_0027 ART_0027 ART_0028 ART_0028 ART_0030 ART_0030 ART_0215 ART_0215 ART_0689 ART_0689 ART_0691 ART_0691 ART_0717 ART_0717 ART_1556 ART_1556 ART_1748 ART_1748 ART_1750 ART_1750 ART_1759 ART_1759 ART_1760 ART_1760 ART_1761 ART_1761 ART_1768 ART_1768 ART_1770 ART_1770 ART_2137 ART_2137 ART_2256 ART_2256 ackA ackA ART_2333 ART_2333 ART_2402 ART_2402 ART_2469 ART_2469 ldh ldh acsA acsA ART_3450 ART_3450 ART_3498 ART_3498 sucC sucC sucD sucD ART_4071 ART_4071 ART_4090 ART_4090 ART_4229 ART_4229
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ART_0027Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (309 aa)
ART_00282-methylcitrate dehydratase; COG2079. (506 aa)
ART_0030Acyl-coenzyme A synthetase; COG0365. (644 aa)
ART_0215Dihydrolipoamide dehydrogenase; COG1249. (460 aa)
ART_0689acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (452 aa)
ART_0691acyl-CoA oxidase; COG1960. (691 aa)
ART_0717acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa)
ART_1556Acetyl-coenzyme A synthetase; COG0365. (576 aa)
ART_1748Putative enoyl-CoA hydratase; COG1024; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
ART_17503-hydroxyisobutyryl-CoA hydrolase; COG1024. (352 aa)
ART_1759Putative enoyl-CoA hydratase; COG1024; Belongs to the enoyl-CoA hydratase/isomerase family. (303 aa)
ART_17603-hydroxyacyl-CoA dehydrogenase; COG1250. (726 aa)
ART_1761acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa)
ART_1768enoyl-CoA hydratase; COG1024. (262 aa)
ART_1770methylcrotonoyl-CoA carboxylase subunit alpha; COG4770. (675 aa)
ART_2137acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
ART_22564-aminobutyrate aminotransferase; COG0160; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (453 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (377 aa)
ART_2333Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (700 aa)
ART_2402Methylmalonate-semialdehyde dehydrogenase; COG1012. (495 aa)
ART_2469Acetyl-coenzyme A synthetase; COG0365. (590 aa)
ldhLactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (317 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa)
ART_3450acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
ART_3498acyl-CoA carboxylase subunit alpha; COG4770. (587 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa)
ART_4071acetyl/propionyl-CoA carboxylase subunit alpha; COG4770. (600 aa)
ART_4090propionyl-CoA carboxylase subunit beta; COG4799. (527 aa)
ART_4229Putative carbamoyl-phosphate synthase subunit; COG4770. (722 aa)
Your Current Organism:
Arthrobacter sp. PAMC25486
NCBI taxonomy Id: 1494608
Other names: A. sp. PAMC 25486, Arthrobacter sp. PAMC 25486
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