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| | ART_0020 | 2-keto-3-deoxygluconate kinase; COG0524. (347 aa) |
| | ART_0023 | 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; COG0800. (211 aa) |
| | gcvH | Putative glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (128 aa) |
| | gcvP | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (924 aa) |
| | ART_0092 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1131 aa) |
| | ART_0094 | Glucokinase; COG1940. (348 aa) |
| | ART_0134 | Polyphosphate ATP-glucomannokinase; COG1940. (264 aa) |
| | ART_0214 | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; COG0508. (591 aa) |
| | ART_0215 | Dihydrolipoamide dehydrogenase; COG1249. (460 aa) |
| | ART_0217 | Aminomethyltransferase; COG0404. (377 aa) |
| | ART_0251 | Aconitase; COG1048. (941 aa) |
| | ART_0281 | Ribulose-5-phosphate 3-epimerase; COG0036; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa) |
| | ART_0302 | Pyruvate kinase; COG0469; Belongs to the pyruvate kinase family. (461 aa) |
| | ART_0324 | Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (715 aa) |
| | ART_0337 | Transketolase; COG0021. (632 aa) |
| | ART_0338 | Dihydrolipoyllysine-residue acetyltransferase; COG0508. (421 aa) |
| | ART_0339 | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (341 aa) |
| | pdhA | Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (390 aa) |
| | ART_0343 | Succinate dehydrogenase/fumarate reductase iron-sulfur subunit; COG0479. (249 aa) |
| | ART_0344 | Hypothetical protein; COG1053. (648 aa) |
| | ART_0345 | Succinate dehydrogenase, cytochrome b subunit. (238 aa) |
| | ART_0448 | Succinate dehydrogenase, flavoprotein subunit; COG1053. (579 aa) |
| | ART_0647 | Aconitate hydratase; COG1048. (934 aa) |
| | ART_0689 | acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (452 aa) |
| | ART_0691 | acyl-CoA oxidase; COG1960. (691 aa) |
| | ART_0705 | Phosphoserine phosphatase; COG0560. (304 aa) |
| | ART_0717 | acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (411 aa) |
| | ART_0731 | Transketolase; COG0021; Belongs to the transketolase family. (708 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (373 aa) |
| | ART_0733 | Glucose-6-phosphate isomerase; COG0166. (545 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (514 aa) |
| | pgl | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (267 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (271 aa) |
| | pgk | Phosphoglycerate kinase; COG0126; Belongs to the phosphoglycerate kinase family. (412 aa) |
| | ART_0740 | Glyceraldehyde-3-phosphate dehydrogenase; COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | ART_0807 | Threonine dehydratase; COG1171. (310 aa) |
| | ART_1023 | 5,10-methylenetetrahydrofolate reductase; COG0685; Belongs to the methylenetetrahydrofolate reductase family. (322 aa) |
| | ART_1069 | Ribose 5-phosphate isomerase; COG0698. (157 aa) |
| | ART_1126 | Glyceraldehyde-3-phosphate dehydrogenase; COG0057; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (493 aa) |
| | ART_1132 | Cysteine synthase; COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family. (311 aa) |
| | ART_1133 | Serine O-acetyltransferase; COG1045. (195 aa) |
| | ART_1136 | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa) |
| | ART_1148 | Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (915 aa) |
| | zwf-2 | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (506 aa) |
| | ART_1350 | Dehydrogenase; COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa) |
| | ART_1356 | D-3-phosphoglycerate dehydrogenase; COG0111; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | ART_1360 | Glucokinase; COG1940. (292 aa) |
| | mqo | Malate:quinone oxidoreductase; COG0579. (499 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (441 aa) |
| | ART_1489 | L-serine dehydratase SdaA; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. (457 aa) |
| | ART_1506 | Cysteine synthase; COG0031. (369 aa) |
| | ART_1517 | Thermoresistant glucokinase family carbohydrate kinase; COG3265. (179 aa) |
| | ART_1524 | Thermoresistant glucokinase family carbohydrate kinase; COG3265. (173 aa) |
| | ART_1540 | 2-oxoglutarate decarboxylase; COG0567. (1264 aa) |
| | ART_1556 | Acetyl-coenzyme A synthetase; COG0365. (576 aa) |
| | ART_1760 | 3-hydroxyacyl-CoA dehydrogenase; COG1250. (726 aa) |
| | ART_1761 | acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (407 aa) |
| | ART_1770 | methylcrotonoyl-CoA carboxylase subunit alpha; COG4770. (675 aa) |
| | ART_1825 | Serine-pyruvate aminotransferase; COG0075. (365 aa) |
| | ART_1854 | L-serine dehydratase; COG1760; Belongs to the iron-sulfur dependent L-serine dehydratase family. (465 aa) |
| | glyA-2 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (438 aa) |
| | gcvH-2 | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa) |
| | gcvT | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (377 aa) |
| | gcvP-2 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (956 aa) |
| | ART_1897 | Putative citrate synthase; COG0372; Belongs to the citrate synthase family. (427 aa) |
| | mdh | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa) |
| | ART_2137 | acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa) |
| | ART_2220 | Ribose 5-phosphate isomerase; COG0698. (152 aa) |
| | ART_2241 | Putative catalase; COG0753; Belongs to the catalase family. (488 aa) |
| | ART_2323 | 3-hydroxyacyl-CoA dehydrogenase; COG1250. (267 aa) |
| | ART_2324 | Hypothetical protein; COG1024. (265 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (377 aa) |
| | ART_2333 | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (700 aa) |
| | ART_2402 | Methylmalonate-semialdehyde dehydrogenase; COG1012. (495 aa) |
| | ART_2452 | Putative fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa) |
| | ART_2461 | Hypothetical protein; COG0524. (323 aa) |
| | ART_2462 | Hypothetical protein; COG0800. (218 aa) |
| | ART_2469 | Acetyl-coenzyme A synthetase; COG0365. (590 aa) |
| | ART_2636 | Formaldehyde dehydrogenase; COG1063. (403 aa) |
| | ART_2767 | Putative 6-phosphogluconate dehydrogenase; COG1023. (285 aa) |
| | ART_2857 | Pyruvate dehydrogenase E1 component, alpha subunit; COG1071. (421 aa) |
| | ART_2858 | Pyruvate dehydrogenase E1 component, beta subunit; COG0022. (321 aa) |
| | ART_2859 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; COG0508. (488 aa) |
| | acsA | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (658 aa) |
| | ART_3157 | Malate synthase A; COG2225; Belongs to the malate synthase family. (549 aa) |
| | ART_3158 | Isocitrate lyase; COG2224. (440 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (939 aa) |
| | ART_3266 | Glucokinase; COG1940. (310 aa) |
| | gpmA | Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (248 aa) |
| | ART_3450 | acetyl-CoA acetyltransferase; COG0183; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | ART_3458 | Fumarate reductase flavoprotein subunit; COG1053. (471 aa) |
| | ART_3498 | acyl-CoA carboxylase subunit alpha; COG4770. (587 aa) |
| | ART_3540 | Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide. (723 aa) |
| | ART_3572 | Putative 3-hydroxyacyl-CoA dehydrogenase; COG1250. (275 aa) |
| | ART_3576 | Glycine dehydrogenase subunit 2; COG1003. (505 aa) |
| | ART_3577 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (470 aa) |
| | ART_3715 | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (375 aa) |
| | sucC | succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (389 aa) |
| | sucD | succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (300 aa) |
| | ART_3796 | Ribose 5-phosphate isomerase; COG0698. (162 aa) |
| | ART_3797 | 3-hydroxyacyl-CoA dehydrogenase; COG1250. (325 aa) |
| | ART_3835 | succinyl-CoA:coenzyme A transferase; COG0427. (503 aa) |
| | ART_3866 | Isocitrate dehydrogenase; COG2838; Belongs to the monomeric-type IDH family. (739 aa) |
| | glyA-3 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (428 aa) |
| | folD | Bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa) |
| | ART_3897 | Succinate dehydrogenase iron-sulfur protein; COG0479; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (263 aa) |
| | ART_3898 | Succinate dehydrogenase, flavoprotein subunit; COG1053. (599 aa) |
| | ART_3899 | Succinate dehydrogenase hydrophobic membrane anchor protein; COG2142. (155 aa) |
| | ART_3900 | Succinate dehydrogenase cytochrome, b-556 subunit; COG2009. (111 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (426 aa) |
| | ART_3930 | Threonine dehydratase; COG1171. (412 aa) |
| | fumC | Fumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (476 aa) |
| | ART_3956 | Fructose 1,6-bisphosphatase; COG1494. (343 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (314 aa) |
| | ART_4071 | acetyl/propionyl-CoA carboxylase subunit alpha; COG4770. (600 aa) |
| | ART_4090 | propionyl-CoA carboxylase subunit beta; COG4799. (527 aa) |
| | ART_4119 | Hypothetical protein; COG1940. (140 aa) |
| | ART_4164 | Hypothetical protein; COG1940. (348 aa) |
| | ART_4166 | Fructose-bisphosphate aldolase; COG0191. (279 aa) |
| | ART_4181 | Hypothetical protein; COG2706. (374 aa) |
| | ART_4222 | Pyruvate dehydrogenase (acetyl-transferring); COG1071. (380 aa) |
| | ART_4223 | Pyruvate dehydrogenase E1 component, beta subunit; COG0022. (336 aa) |
| | ART_4224 | Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase component; COG0508. (451 aa) |
| | ART_4229 | Putative carbamoyl-phosphate synthase subunit; COG4770. (722 aa) |
