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purM purM EL22_07595 EL22_07595 panB panB EL22_07845 EL22_07845 glpK glpK ribK ribK carS carS EL22_08025 EL22_08025 EL22_08070 EL22_08070 mptA mptA EL22_08600 EL22_08600 EL22_09200 EL22_09200 EL22_10025 EL22_10025 purA purA purS purS purQ purQ EL22_11360 EL22_11360 EL22_11735 EL22_11735 EL22_11745 EL22_11745 EL22_12435 EL22_12435 purL purL EL22_13290 EL22_13290 nadX nadX glmS-3 glmS-3 carA carA EL22_27780 EL22_27780 EL22_27005 EL22_27005 pyrI pyrI EL22_26830 EL22_26830 EL22_26565 EL22_26565 nadA nadA pgi pgi pyrG pyrG guaAB guaAB EL22_24640 EL22_24640 EL22_24625 EL22_24625 EL22_24570 EL22_24570 EL22_24430 EL22_24430 atpE atpE atpC atpC atpF atpF atpA atpA atpB atpB EL22_23950 EL22_23950 EL22_23690 EL22_23690 purC purC EL22_23415 EL22_23415 ndk ndk mvk mvk eno eno moaA moaA EL22_23160 EL22_23160 ribL ribL EL22_23070 EL22_23070 moaC moaC pyrF pyrF cmk cmk adk adk pyrB pyrB EL22_21700 EL22_21700 thiI thiI EL22_21335 EL22_21335 EL22_21310 EL22_21310 EL22_21040 EL22_21040 EL22_21025 EL22_21025 EL22_20985 EL22_20985 EL22_20875 EL22_20875 ubiA ubiA EL22_20110 EL22_20110 EL22_19335 EL22_19335 EL22_19240 EL22_19240 nadK nadK gap gap EL22_17665 EL22_17665 purF purF EL22_16790 EL22_16790 EL22_16785 EL22_16785 EL22_16190 EL22_16190 EL22_15300 EL22_15300 pdxT pdxT cofE cofE EL22_15075 EL22_15075 EL22_15070 EL22_15070 glmS-4 glmS-4 tdk tdk cofC cofC EL22_01980 EL22_01980 EL22_01995 EL22_01995 EL22_02085 EL22_02085 EL22_02360 EL22_02360 EL22_02480 EL22_02480 EL22_02590 EL22_02590 guaB guaB EL22_02915 EL22_02915 cofD cofD EL22_02985 EL22_02985 EL22_02990 EL22_02990 tpiA tpiA EL22_03325 EL22_03325 EL22_03330 EL22_03330 pyrH pyrH EL22_03415 EL22_03415 prs prs EL22_04205 EL22_04205 purO purO EL22_04255 EL22_04255 EL22_04525 EL22_04525 EL22_04590 EL22_04590 pdxS pdxS EL22_05100 EL22_05100 EL22_05160 EL22_05160 EL22_05460 EL22_05460 EL22_05470 EL22_05470 thiL thiL EL22_05640 EL22_05640 EL22_05690 EL22_05690 pgk pgk EL22_05910 EL22_05910 EL22_05935 EL22_05935 upp upp EL22_06115 EL22_06115 EL22_06120 EL22_06120 EL22_00155 EL22_00155 EL22_00165 EL22_00165 surE surE EL22_00590 EL22_00590 dcd dcd EL22_00990 EL22_00990 purK purK purE purE EL22_01255 EL22_01255 deoC deoC EL22_06290 EL22_06290 thiE thiE thiM thiM mobA mobA EL22_06685 EL22_06685 EL22_06735 EL22_06735 pyrE pyrE EL22_06795 EL22_06795 EL22_06870 EL22_06870 EL22_07145 EL22_07145 EL22_07430 EL22_07430 thyA thyA purD purD EL22_07560 EL22_07560
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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purMPhosphoribosylaminoimidazole synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
EL22_07595acyl-CoA thioester hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (270 aa)
EL22_07845Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (513 aa)
ribKRiboflavin kinase; Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN); Belongs to the archaeal riboflavin kinase family. (234 aa)
carSHypothetical protein; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. (181 aa)
EL22_08025Orotate phosphoribosyltransferase-like protein; Purine/pyrimidine phosphoribosyltransferase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
EL22_08070acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
mptAGTP cyclohydrolase; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin. (312 aa)
EL22_08600Electron transfer flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
EL22_09200Nicotinate phosphoribosyltransferase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
EL22_100252-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (299 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (454 aa)
purSPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (84 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (226 aa)
EL22_11360DNA/pantothenate metabolism flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
EL22_11735Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (490 aa)
EL22_117452-oxo acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
EL22_12435Molybdenum cofactor biosynthesis protein MoaA; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
purLPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (753 aa)
EL22_13290Hypothetical protein; Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. (173 aa)
nadXAspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (274 aa)
glmS-3Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (602 aa)
carACarbamoyl phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (357 aa)
EL22_27780Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
EL22_27005Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
pyrIAspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase. (142 aa)
EL22_26830Zeaxanthin epoxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
EL22_26565Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (77 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (377 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (431 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (557 aa)
guaABGMP synthase [glutamine-hydrolyzing] subunit B; Catalyzes the synthesis of GMP from XMP. (305 aa)
EL22_24640Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
EL22_24625Isopentenyl-diphosphate delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
EL22_24570Electron transfer flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
EL22_24430acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
atpEATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane. (193 aa)
atpCATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane. (350 aa)
atpFATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane. (110 aa)
atpAATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family. (587 aa)
atpBATP synthase subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (474 aa)
EL22_23950Nicotinate-nucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
EL22_23690Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
purCPhosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
EL22_23415Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (154 aa)
mvkMevalonate kinase; Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)- mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids; Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (328 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (401 aa)
moaARadical SAM protein; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family. (350 aa)
EL22_23160Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
ribLFAD synthase; Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme. (155 aa)
EL22_23070acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)
moaCCyclic pyranopterin monophosphate synthase; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (182 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (266 aa)
cmkCytidylate kinase; Catalyzes the formation of (d)CDP from ATP and (d)CMP; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (211 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
EL22_21700Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
thiItRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (392 aa)
EL22_21335Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
EL22_21310Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (491 aa)
EL22_21040Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
EL22_21025Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
EL22_20985Geranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (233 aa)
EL22_20875Inositol monophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
ubiAPrenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (283 aa)
EL22_20110Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
EL22_19335Molybdenum cofactor biosynthesis protein MoaB; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
EL22_19240Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
nadKInorganic polyphosphate kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (280 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glycerol phosphate from D-glyceraldehyde 3-phosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
EL22_17665Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (490 aa)
EL22_16790Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa)
EL22_16785N-acetylglucosamine-1-phosphate uridyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
EL22_16190Aspartate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
EL22_15300NAD+ synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD synthetase family. (293 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (204 aa)
cofEF420-0--gamma-glutamyl ligase; Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8- didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420- 0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives. (256 aa)
EL22_15075Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (122 aa)
EL22_15070NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
glmS-4Glucosamine-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (638 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
cofC2-phospho-L-lactate guanylyltransferase; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family. (216 aa)
EL22_01980Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
EL22_01995FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (411 aa)
EL22_02085hydroxymethylglutaryl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
EL22_023606-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH. (299 aa)
EL22_02480Rhodanese; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
EL22_02590Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (502 aa)
guaBInosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (500 aa)
EL22_02915Electron transfer flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
cofD2-phospho-L-lactate transferase; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP. (330 aa)
EL22_02985Adenylate kinase; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (186 aa)
EL22_02990CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (204 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (214 aa)
EL22_03325Hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (189 aa)
EL22_03330Electron transfer flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
EL22_03415Bifunctional molybdopterin-guanine dinucleotide biosynthesis protein MobB/MoaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P). (282 aa)
EL22_04205Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
purOIMP cyclohydrolase; Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP. (196 aa)
EL22_04255Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
EL22_04525CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (251 aa)
EL22_04590NUDIX hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (186 aa)
pdxSPyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (302 aa)
EL22_051003-hydroxy-3-methylglutaryl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HMG-CoA reductase family. (407 aa)
EL22_05160HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
EL22_05460acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
EL22_05470Farnesyl-diphosphate farnesyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (314 aa)
EL22_05640Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
EL22_05690Deoxyribonucleotide triphosphate pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HAM1 NTPase family. (182 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (404 aa)
EL22_05910methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
EL22_05935acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (225 aa)
EL22_06115Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (462 aa)
EL22_06120Phosphoribosylglycinamide formyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (561 aa)
EL22_00155acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (658 aa)
EL22_00165acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (657 aa)
surE5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (263 aa)
EL22_00590Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (200 aa)
EL22_00990Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
purKPhosphoribosylaminoimidazole carboxylase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (412 aa)
purE1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (212 aa)
EL22_01255Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (226 aa)
EL22_06290acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (674 aa)
thiEThiamine-phosphate synthase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (231 aa)
thiMHydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (277 aa)
mobAMolybdenum cofactor guanylyltransferase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor. (216 aa)
EL22_06685Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
EL22_06735Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (174 aa)
EL22_06795HIT family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
EL22_06870DRTGG domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
EL22_07145Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
EL22_07430Deoxyuridine 5'-triphosphate nucleotidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (338 aa)
purDPhosphoribosylamine--glycine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (430 aa)
EL22_07560Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (489 aa)
Your Current Organism:
Halostagnicola sp. A56
NCBI taxonomy Id: 1495067
Other names: H. sp. A56
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