(13 nodes) Mixed, incl. D-Glutamine and D-glutamate metabolism, and Glutamate synthase domain network (Burkholderia stagnalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOK51600.1	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1567 aa)
	gltD	Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
	AOK51829.1	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (428 aa)
	AOK51853.1	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family. (539 aa)
	AOK52939.1	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
	glnA	Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
	murI	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (286 aa)
	AOK54611.1	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
	AOK55070.1	Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily. (349 aa)
	AOK57542.1	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (370 aa)
	AOK56577.1	NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1621 aa)
	glsA	Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family. (304 aa)
	glnA-2	Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)

Your Current Organism:

Burkholderia stagnalis

NCBI taxonomy Id: 1503054
Other names: B. stagnalis, Burkholderia sp. Bp6893, Burkholderia sp. Bp6916, Burkholderia sp. Bp7118, Burkholderia sp. Bp7119, Burkholderia sp. Bp7120, Burkholderia sp. Bp7137, Burkholderia sp. Bp7139, Burkholderia sp. Bp7142, Burkholderia sp. Bp7143, Burkholderia sp. Bp7145, Burkholderia sp. Bp7260, Burkholderia sp. Bp7266, Burkholderia sp. Bp7278, Burkholderia sp. Bp7280, Burkholderia sp. Bp7282, Burkholderia sp. Bp7288, Burkholderia sp. Bp7466, Burkholderia sp. Bp7469, Burkholderia sp. Bp7471, Burkholderia sp. Bp7483, Burkholderia sp. Bp7485, Burkholderia sp. Bp7491, Burkholderia sp. Bp7519, Burkholderia sp. Bp7520, Burkholderia sp. Bp7521, Burkholderia sp. Bp7554, Burkholderia sp. Bp7555, Burkholderia sp. Bp7571, Burkholderia sp. Bp7572, Burkholderia sp. Bp7635, Burkholderia sp. Bp7636, Burkholderia sp. Bp7639, Burkholderia sp. Bp7640, Burkholderia sp. Bp7641, Burkholderia sp. Bp7642, Burkholderia sp. Bp7643, Burkholderia sp. Bp7644, Burkholderia sp. Bp7645, Burkholderia sp. Bp7651, Burkholderia sp. Bp7656, Burkholderia sp. Bp7657, Burkholderia sp. Bp7658, Burkholderia sp. Bp7663, Burkholderia sp. Bp7665, Burkholderia sp. Bp7666, Burkholderia sp. Bp7667, Burkholderia sp. Bp7670, Burkholderia sp. Bp7671, Burkholderia sp. Bp7673, Burkholderia sp. Bp7681, Burkholderia sp. Bp7682, Burkholderia sp. Bp7684, Burkholderia sp. Bp7685, Burkholderia sp. Bp7686, Burkholderia sp. Bp7687, Burkholderia sp. Bp7690, Burkholderia sp. Bp7692, Burkholderia sp. Bp7693, Burkholderia sp. Bp7694, Burkholderia sp. Bp7697, Burkholderia sp. Bp7698, Burkholderia sp. Bp7699, Burkholderia sp. Bp7705, Burkholderia sp. Bp7707, Burkholderia sp. LMG 28156, Burkholderia sp. LMG 28157, Burkholderia sp. R-52095, Burkholderia sp. R-52096, Burkholderia sp. R-52235, Burkholderia sp. R-52237, Burkholderia sp. R-52238, Burkholderia sp. R-52240, Burkholderia stagnalis De Smet et al. 2015, CCUG 65686, LMG 28156, LMG:28156

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOK51600.1	AOK51829.1	WT74_01995	WT74_03290	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.996
AOK51600.1	AOK51853.1	WT74_01995	WT74_03420	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family.	0.966
AOK51600.1	AOK52939.1	WT74_01995	WT74_09710	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.517
AOK51600.1	AOK54611.1	WT74_01995	WT74_17370	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Dihydropyrimidine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOK51600.1	AOK55070.1	WT74_01995	WT74_20040	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.	0.800
AOK51600.1	AOK56577.1	WT74_01995	WT74_28300	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
AOK51600.1	AOK57542.1	WT74_01995	WT74_27235	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.996
AOK51600.1	glnA	WT74_01995	WT74_11225	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
AOK51600.1	glnA-2	WT74_01995	WT74_30690	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
AOK51600.1	glsA	WT74_01995	WT74_29880	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the formation of glutamate from glutamine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaminase family.	0.941
AOK51600.1	gltD	WT74_01995	WT74_02000	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AOK51600.1	murI	WT74_01995	WT74_11605	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.	0.528
AOK51829.1	AOK51600.1	WT74_03290	WT74_01995	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
AOK51829.1	AOK51853.1	WT74_03290	WT74_03420	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate synthase family.	0.735
AOK51829.1	AOK52939.1	WT74_03290	WT74_09710	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.913
AOK51829.1	AOK55070.1	WT74_03290	WT74_20040	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Succinylglutamate desuccinylase; Transforms N(2)-succinylglutamate into succinate and glutamate; Belongs to the AspA/AstE family. Succinylglutamate desuccinylase subfamily.	0.804
AOK51829.1	AOK56577.1	WT74_03290	WT74_28300	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.916
AOK51829.1	AOK57542.1	WT74_03290	WT74_27235	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.922
AOK51829.1	glnA	WT74_03290	WT74_11225	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.912
AOK51829.1	glnA-2	WT74_03290	WT74_30690	Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.912

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