(6 nodes) Two-component regulatory system network (Burkholderia stagnalis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AOK51341.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
	AOK51342.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
	AOK53024.1	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
	AOK53025.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
	AOK53512.1	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
	ompR	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)

Your Current Organism:

Burkholderia stagnalis

NCBI taxonomy Id: 1503054
Other names: B. stagnalis, Burkholderia sp. Bp6893, Burkholderia sp. Bp6916, Burkholderia sp. Bp7118, Burkholderia sp. Bp7119, Burkholderia sp. Bp7120, Burkholderia sp. Bp7137, Burkholderia sp. Bp7139, Burkholderia sp. Bp7142, Burkholderia sp. Bp7143, Burkholderia sp. Bp7145, Burkholderia sp. Bp7260, Burkholderia sp. Bp7266, Burkholderia sp. Bp7278, Burkholderia sp. Bp7280, Burkholderia sp. Bp7282, Burkholderia sp. Bp7288, Burkholderia sp. Bp7466, Burkholderia sp. Bp7469, Burkholderia sp. Bp7471, Burkholderia sp. Bp7483, Burkholderia sp. Bp7485, Burkholderia sp. Bp7491, Burkholderia sp. Bp7519, Burkholderia sp. Bp7520, Burkholderia sp. Bp7521, Burkholderia sp. Bp7554, Burkholderia sp. Bp7555, Burkholderia sp. Bp7571, Burkholderia sp. Bp7572, Burkholderia sp. Bp7635, Burkholderia sp. Bp7636, Burkholderia sp. Bp7639, Burkholderia sp. Bp7640, Burkholderia sp. Bp7641, Burkholderia sp. Bp7642, Burkholderia sp. Bp7643, Burkholderia sp. Bp7644, Burkholderia sp. Bp7645, Burkholderia sp. Bp7651, Burkholderia sp. Bp7656, Burkholderia sp. Bp7657, Burkholderia sp. Bp7658, Burkholderia sp. Bp7663, Burkholderia sp. Bp7665, Burkholderia sp. Bp7666, Burkholderia sp. Bp7667, Burkholderia sp. Bp7670, Burkholderia sp. Bp7671, Burkholderia sp. Bp7673, Burkholderia sp. Bp7681, Burkholderia sp. Bp7682, Burkholderia sp. Bp7684, Burkholderia sp. Bp7685, Burkholderia sp. Bp7686, Burkholderia sp. Bp7687, Burkholderia sp. Bp7690, Burkholderia sp. Bp7692, Burkholderia sp. Bp7693, Burkholderia sp. Bp7694, Burkholderia sp. Bp7697, Burkholderia sp. Bp7698, Burkholderia sp. Bp7699, Burkholderia sp. Bp7705, Burkholderia sp. Bp7707, Burkholderia sp. LMG 28156, Burkholderia sp. LMG 28157, Burkholderia sp. R-52095, Burkholderia sp. R-52096, Burkholderia sp. R-52235, Burkholderia sp. R-52237, Burkholderia sp. R-52238, Burkholderia sp. R-52240, Burkholderia stagnalis De Smet et al. 2015, CCUG 65686, LMG 28156, LMG:28156

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOK51341.1	AOK51342.1	WT74_00520	WT74_00525	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
AOK51341.1	AOK53024.1	WT74_00520	WT74_10160	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
AOK51341.1	ompR	WT74_00520	WT74_12875	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
AOK51342.1	AOK51341.1	WT74_00525	WT74_00520	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
AOK51342.1	AOK53025.1	WT74_00525	WT74_10165	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.740
AOK51342.1	AOK53512.1	WT74_00525	WT74_12870	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.797
AOK53024.1	AOK51341.1	WT74_10160	WT74_00520	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.678
AOK53024.1	AOK53025.1	WT74_10160	WT74_10165	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
AOK53024.1	AOK53512.1	WT74_10160	WT74_12870	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
AOK53024.1	ompR	WT74_10160	WT74_12875	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903
AOK53025.1	AOK51342.1	WT74_10165	WT74_00525	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.740
AOK53025.1	AOK53024.1	WT74_10165	WT74_10160	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.994
AOK53025.1	AOK53512.1	WT74_10165	WT74_12870	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
AOK53025.1	ompR	WT74_10165	WT74_12875	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
AOK53512.1	AOK51342.1	WT74_12870	WT74_00525	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.797
AOK53512.1	AOK53024.1	WT74_12870	WT74_10160	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.983
AOK53512.1	AOK53025.1	WT74_12870	WT74_10165	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.923
AOK53512.1	ompR	WT74_12870	WT74_12875	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
ompR	AOK51341.1	WT74_12875	WT74_00520	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
ompR	AOK53024.1	WT74_12875	WT74_10160	Part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation; Derived by automated computational analysis using gene prediction method: Protein Homology.	Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.903

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