STRINGSTRING
AOK51289.1 AOK51289.1 flhD flhD tpx tpx AOK54249.1 AOK54249.1 AOK51913.1 AOK51913.1 flhD-2 flhD-2 dsbB dsbB rlmN rlmN AOK52917.1 AOK52917.1 ahpD ahpD AOK53174.1 AOK53174.1 AOK53932.1 AOK53932.1 AOK53978.1 AOK53978.1 AOK54594.1 AOK54594.1 dsbB-2 dsbB-2 AOK55365.1 AOK55365.1 AOK55990.1 AOK55990.1 ahpC ahpC WT74_25795 WT74_25795 AOK56913.1 AOK56913.1 AOK57608.1 AOK57608.1 AOK57077.1 AOK57077.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOK51289.1Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (157 aa)
flhDTranscriptional regulator; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (106 aa)
tpxThiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (167 aa)
AOK54249.1Redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AOK51913.1Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (109 aa)
flhD-2Flagellar transcriptional regulator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (105 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (170 aa)
rlmN23S rRNA (adenine(2503)-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (379 aa)
AOK52917.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (108 aa)
ahpDCarboxymuconolactone decarboxylase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (175 aa)
AOK53174.1Hsp33 chaperonin; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress; Belongs to the HSP33 family. (316 aa)
AOK53932.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
AOK53978.1Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AOK54594.1Alkylhydroperoxidase; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (159 aa)
dsbB-2Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (167 aa)
AOK55365.1Redoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
AOK55990.1Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
ahpCAlkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
WT74_25795Hypothetical protein; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family. (145 aa)
AOK56913.1Amine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
AOK57608.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
AOK57077.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
Your Current Organism:
Burkholderia stagnalis
NCBI taxonomy Id: 1503054
Other names: B. stagnalis, Burkholderia sp. Bp6893, Burkholderia sp. Bp6916, Burkholderia sp. Bp7118, Burkholderia sp. Bp7119, Burkholderia sp. Bp7120, Burkholderia sp. Bp7137, Burkholderia sp. Bp7139, Burkholderia sp. Bp7142, Burkholderia sp. Bp7143, Burkholderia sp. Bp7145, Burkholderia sp. Bp7260, Burkholderia sp. Bp7266, Burkholderia sp. Bp7278, Burkholderia sp. Bp7280, Burkholderia sp. Bp7282, Burkholderia sp. Bp7288, Burkholderia sp. Bp7466, Burkholderia sp. Bp7469, Burkholderia sp. Bp7471, Burkholderia sp. Bp7483, Burkholderia sp. Bp7485, Burkholderia sp. Bp7491, Burkholderia sp. Bp7519, Burkholderia sp. Bp7520, Burkholderia sp. Bp7521, Burkholderia sp. Bp7554, Burkholderia sp. Bp7555, Burkholderia sp. Bp7571, Burkholderia sp. Bp7572, Burkholderia sp. Bp7635, Burkholderia sp. Bp7636, Burkholderia sp. Bp7639, Burkholderia sp. Bp7640, Burkholderia sp. Bp7641, Burkholderia sp. Bp7642, Burkholderia sp. Bp7643, Burkholderia sp. Bp7644, Burkholderia sp. Bp7645, Burkholderia sp. Bp7651, Burkholderia sp. Bp7656, Burkholderia sp. Bp7657, Burkholderia sp. Bp7658, Burkholderia sp. Bp7663, Burkholderia sp. Bp7665, Burkholderia sp. Bp7666, Burkholderia sp. Bp7667, Burkholderia sp. Bp7670, Burkholderia sp. Bp7671, Burkholderia sp. Bp7673, Burkholderia sp. Bp7681, Burkholderia sp. Bp7682, Burkholderia sp. Bp7684, Burkholderia sp. Bp7685, Burkholderia sp. Bp7686, Burkholderia sp. Bp7687, Burkholderia sp. Bp7690, Burkholderia sp. Bp7692, Burkholderia sp. Bp7693, Burkholderia sp. Bp7694, Burkholderia sp. Bp7697, Burkholderia sp. Bp7698, Burkholderia sp. Bp7699, Burkholderia sp. Bp7705, Burkholderia sp. Bp7707, Burkholderia sp. LMG 28156, Burkholderia sp. LMG 28157, Burkholderia sp. R-52095, Burkholderia sp. R-52096, Burkholderia sp. R-52235, Burkholderia sp. R-52237, Burkholderia sp. R-52238, Burkholderia sp. R-52240, Burkholderia stagnalis De Smet et al. 2015, CCUG 65686, LMG 28156, LMG:28156
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