node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AJY50046.1 | AJY50047.1 | KO116_01561 | KO116_01562 | KEGG: amino acid permease; PFAM: amino acid permease-associated region. | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | 0.950 |
AJY50047.1 | AJY50046.1 | KO116_01562 | KO116_01561 | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | KEGG: amino acid permease; PFAM: amino acid permease-associated region. | 0.950 |
AJY50047.1 | AJY50490.1 | KO116_01562 | KO116_02011 | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | 0.905 |
AJY50047.1 | AJY50705.1 | KO116_01562 | KO116_02230 | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.939 |
AJY50047.1 | metE | KO116_01562 | KO116_01041 | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.931 |
AJY50047.1 | metK | KO116_01562 | KO116_04244 | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.930 |
AJY50490.1 | AJY50047.1 | KO116_02011 | KO116_01562 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | KEGG: ybgG; homocysteine S-methyltransferase; PFAM: homocysteine S-methyltransferase. | 0.905 |
AJY50490.1 | AJY50491.1 | KO116_02011 | KO116_02012 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | 0.708 |
AJY50490.1 | AJY50492.1 | KO116_02011 | KO116_02013 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | PFAM: ABC-type transporter, integral membrane subunit; KEGG: ABC transporter permease. | 0.464 |
AJY50490.1 | AJY50705.1 | KO116_02011 | KO116_02230 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
AJY50490.1 | metE | KO116_02011 | KO116_01041 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. | 0.900 |
AJY50490.1 | metK | KO116_02011 | KO116_04244 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.900 |
AJY50490.1 | metN | KO116_02011 | KO116_02014 | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | Phosphonate-transporting ATPase; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.464 |
AJY50491.1 | AJY50490.1 | KO116_02012 | KO116_02011 | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | 0.708 |
AJY50491.1 | AJY50492.1 | KO116_02012 | KO116_02013 | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | PFAM: ABC-type transporter, integral membrane subunit; KEGG: ABC transporter permease. | 0.999 |
AJY50491.1 | AJY52702.1 | KO116_02012 | KO116_04241 | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; KEGG: metF; 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. | 0.439 |
AJY50491.1 | metK | KO116_02012 | KO116_04244 | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.467 |
AJY50491.1 | metN | KO116_02012 | KO116_02014 | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | Phosphonate-transporting ATPase; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. | 0.999 |
AJY50492.1 | AJY50490.1 | KO116_02013 | KO116_02011 | PFAM: ABC-type transporter, integral membrane subunit; KEGG: ABC transporter permease. | KEGG: GAF; GAF domain-containing protein; PFAM: GAF domain protein; SMART: GAF domain protein. | 0.464 |
AJY50492.1 | AJY50491.1 | KO116_02013 | KO116_02012 | PFAM: ABC-type transporter, integral membrane subunit; KEGG: ABC transporter permease. | Lipoprotein, YaeC family; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family; KEGG: ABC transporter periplasmic protein. | 0.999 |