STRINGSTRING
AJY48982.1 AJY48982.1 proC proC AJY49305.1 AJY49305.1 AJY49575.1 AJY49575.1 AJY49576.1 AJY49576.1 AJY50066.1 AJY50066.1 AJY50276.1 AJY50276.1 glsA glsA proA proA AJY50400.1 AJY50400.1 lipB lipB lipA lipA AJY50585.1 AJY50585.1 AJY50586.1 AJY50586.1 AJY50587.1 AJY50587.1 AJY50664.1 AJY50664.1 AJY50774.1 AJY50774.1 gcvH gcvH gcvP gcvP AJY51566.1 AJY51566.1 murI murI AJY51635.1 AJY51635.1 AJY51636.1 AJY51636.1 AJY51637.1 AJY51637.1 AJY52054.1 AJY52054.1 AJY52055.1 AJY52055.1 proC-2 proC-2 proB proB AJY52585.1 AJY52585.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AJY48982.1Glutamate dehydrogenase (NADP(+)); PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerization region; SMART: Glu/Leu/Phe/Val dehydrogenase; KEGG: glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (450 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (276 aa)
AJY49305.1Agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: agmatinase; TIGRFAM: agmatinase; Belongs to the arginase family. (316 aa)
AJY49575.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (890 aa)
AJY49576.1Pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (678 aa)
AJY50066.1PFAM: amidinotransferase; KEGG: gatM; glycine amidinotransferase. (385 aa)
AJY50276.1Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1063 aa)
glsAKEGG: glutaminase; HAMAP : Glutaminase; TIGRFAM: glutaminase A; PFAM: Glutaminase; Belongs to the glutaminase family. (313 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (435 aa)
AJY50400.1UPF0250 protein ybeD; KEGG: hypothetical protein; PFAM: protein of unknown function DUF493; HAMAP : UPF0250 protein ybeD; Belongs to the UPF0250 family. (103 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (194 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (352 aa)
AJY50585.1KEGG: 3-methyl-2-oxobutanoate dehydrogenase; PFAM: dehydrogenase E1 component. (401 aa)
AJY50586.13-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring); PFAM: Transketolase central region; Transketolase domain-containing protein; SMART: Transketolase central region; KEGG: transketolase. (325 aa)
AJY50587.1Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase; KEGG: dihydrolipoamide acetyltransferase; PFAM: catalytic domain-containing protein; biotin/lipoyl attachment domain-containing protein; E3 binding domain-containing protein. (424 aa)
AJY50664.1Dihydrolipoyl dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; pyridine nucleotide-disulfide oxidoreductase dimerization region; KEGG: dihydrolipoamide dehydrogenase. (488 aa)
AJY50774.1PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein barrel; KEGG: gcvT; glycine cleavage system protein T (aminomethyltransferase); TIGRFAM: glycine cleavage system T protein. (370 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (964 aa)
AJY51566.1Hypothetical protein; KEGG: gdh; glutamate dehydrogenase. (1607 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (275 aa)
AJY51635.1KEGG: dihydrolipoamide dehydrogenase; PFAM: pyridine nucleotide-disulfide oxidoreductase dimerization region; FAD-dependent pyridine nucleotide-disulfide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; TIGRFAM: dihydrolipoamide dehydrogenase. (479 aa)
AJY51636.12-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (530 aa)
AJY51637.1TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; SMART: Transketolase central region; KEGG: sucA; 2-oxoglutarate dehydrogenase, E1 component; PFAM: Transketolase central region; dehydrogenase E1 component. (964 aa)
AJY52054.1TIGRFAM: glutamate synthase, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; KEGG: gltD; glutamate synthase (NADPH), small subunit. (472 aa)
AJY52055.1PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; glutamate synthase; KEGG: gltB; glutamate synthase (NADPH), large subunit. (1480 aa)
proC-2Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (274 aa)
proBGlutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa)
AJY52585.1PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; TIGRFAM: glutamine synthetase, type I; KEGG: glnA1; glutamine synthetase. (468 aa)
Your Current Organism:
Halomonas sp. KO116
NCBI taxonomy Id: 1504981
Other names: H. sp. KO116
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.