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pdxS pdxS pdxT pdxT JMA_03510 JMA_03510 JMA_04920 JMA_04920 JMA_08750 JMA_08750 JMA_16370 JMA_16370 JMA_17860 JMA_17860 deoB deoB deoC deoC JMA_24130 JMA_24130 JMA_24280 JMA_24280 pfkA pfkA pgi pgi eno eno gpmI gpmI tpiA tpiA pgk pgk JMA_26950 JMA_26950 JMA_28580 JMA_28580 rpiA rpiA JMA_30420 JMA_30420 tal tal JMA_30460 JMA_30460 fda fda rbsK rbsK JMA_36120 JMA_36120
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pdxSPyridoxal biosynthesis protein; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (293 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (195 aa)
JMA_03510Hypothetical protein. (199 aa)
JMA_04920Phosphoglycerate mutase. (179 aa)
JMA_08750Glucose-6-phosphate isomerase. (121 aa)
JMA_16370Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (217 aa)
JMA_17860Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (668 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (395 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (222 aa)
JMA_24130Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (345 aa)
JMA_24280Pyruvate kinase; Belongs to the pyruvate kinase family. (586 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
pgiGlucose-6-phosphate isomerase; Belongs to the GPI family. (449 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (510 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (253 aa)
pgkPhosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (394 aa)
JMA_26950Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa)
JMA_28580Phosphoglycerate mutase family protein. (194 aa)
rpiARibose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (238 aa)
JMA_30420Fructose 1,6-bisphosphatase. (320 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (214 aa)
JMA_30460Fructose-bisphosphate aldolase. (285 aa)
fdaFructose-bisphosphate aldolase. (297 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (283 aa)
JMA_36120Phosphoglycerate mutase. (185 aa)
Your Current Organism:
Jeotgalibacillus malaysiensis
NCBI taxonomy Id: 1508404
Other names: DSM 28777, J. malaysiensis, Jeotgalibacillus malaysiensis Yaakop et al. 2015, Jeotgalibacillus sp. D5, KCTC 33550, strain D5
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