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speE-2 speE-2 nadA nadA JMA_00910 JMA_00910 JMA_00970 JMA_00970 JMA_04850 JMA_04850 JMA_07220 JMA_07220 thiE thiE pcrB pcrB JMA_11560 JMA_11560 speE speE JMA_13810 JMA_13810 ctaB ctaB JMA_17130 JMA_17130 miaA miaA JMA_36030 JMA_36030 ribH ribH JMA_18900 JMA_18900 aroA aroA JMA_19900 JMA_19900 JMA_20950 JMA_20950 JMA_36340 JMA_36340 hemC hemC JMA_25150 JMA_25150 metK metK menA menA JMA_28170 JMA_28170 murA murA murA-2 murA-2 JMA_30650 JMA_30650 JMA_30780 JMA_30780
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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speE-2Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (276 aa)
nadAQuinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (319 aa)
JMA_00910Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (307 aa)
JMA_00970Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (270 aa)
JMA_04850Glutathione S-transferase. (328 aa)
JMA_07220Hypothetical protein. (433 aa)
thiEThiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (214 aa)
pcrBGeranylgeranylglyceryl phosphate synthase; Prenyltransferase that catalyzes in vivo the transfer of the heptaprenyl moiety of heptaprenyl pyrophosphate (HepPP; 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond- formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales. (225 aa)
JMA_11560UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (228 aa)
speESpermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (520 aa)
JMA_13810Phytoene synthase. (276 aa)
ctaBHeme O synthase, protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group; Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily. (304 aa)
JMA_17130UDP pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (273 aa)
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (306 aa)
JMA_36030N-methyl-transferase-related protein. (246 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. (156 aa)
JMA_18900Riboflavin synthase. (211 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (427 aa)
JMA_19900Hypothetical protein. (258 aa)
JMA_20950Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (292 aa)
JMA_36340Thiamine-phosphate diphosphorylase. (205 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (310 aa)
JMA_25150Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (310 aa)
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
menA1,4-dihydroxy-2-naphthoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (303 aa)
JMA_28170Hypothetical protein. (351 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase 1; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (436 aa)
murA-2UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (428 aa)
JMA_30650ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (194 aa)
JMA_30780Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa)
Your Current Organism:
Jeotgalibacillus malaysiensis
NCBI taxonomy Id: 1508404
Other names: DSM 28777, J. malaysiensis, Jeotgalibacillus malaysiensis Yaakop et al. 2015, Jeotgalibacillus sp. D5, KCTC 33550, strain D5
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