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secE secE rpoB rpoB rpoC rpoC tuf tuf secY secY rpoA rpoA JMA_01810 JMA_01810 JMA_02190 JMA_02190 JMA_02540 JMA_02540 JMA_03670 JMA_03670 JMA_03700 JMA_03700 JMA_03710 JMA_03710 katG katG JMA_04440 JMA_04440 JMA_04660 JMA_04660 JMA_05000 JMA_05000 JMA_05470 JMA_05470 JMA_05970 JMA_05970 JMA_06370 JMA_06370 JMA_06380 JMA_06380 JMA_06680 JMA_06680 JMA_07390 JMA_07390 JMA_07400 JMA_07400 JMA_07410 JMA_07410 JMA_07940 JMA_07940 JMA_07950 JMA_07950 JMA_08120 JMA_08120 JMA_08460 JMA_08460 JMA_09040 JMA_09040 JMA_11680 JMA_11680 JMA_11870 JMA_11870 JMA_11880 JMA_11880 JMA_12410 JMA_12410 JMA_12640 JMA_12640 JMA_12680 JMA_12680 JMA_12930 JMA_12930 JMA_13130 JMA_13130 JMA_13190 JMA_13190 JMA_13200 JMA_13200 JMA_14050 JMA_14050 JMA_14060 JMA_14060 JMA_14070 JMA_14070 JMA_14180 JMA_14180 JMA_15060 JMA_15060 JMA_15110 JMA_15110 JMA_15120 JMA_15120 JMA_15130 JMA_15130 JMA_15230 JMA_15230 rpoZ rpoZ msrA-2 msrA-2 JMA_18720 JMA_18720 JMA_18910 JMA_18910 msrA-3 msrA-3 ndk ndk JMA_20090 JMA_20090 JMA_20250 JMA_20250 JMA_20760 JMA_20760 JMA_21470 JMA_21470 JMA_21490 JMA_21490 secD secD JMA_23680 JMA_23680 JMA_23820 JMA_23820 JMA_24380 JMA_24380 tpx tpx JMA_24940 JMA_24940 JMA_25260 JMA_25260 JMA_25290 JMA_25290 JMA_25790 JMA_25790 JMA_26010 JMA_26010 JMA_26870 JMA_26870 JMA_27580 JMA_27580 secA secA JMA_30210 JMA_30210 JMA_31240 JMA_31240 JMA_31250 JMA_31250 JMA_31260 JMA_31260 JMA_31420 JMA_31420 arsC arsC JMA_31650 JMA_31650 JMA_32840 JMA_32840 JMA_32960 JMA_32960 JMA_32970 JMA_32970 JMA_33480 JMA_33480 JMA_33560 JMA_33560 JMA_33660 JMA_33660 JMA_33670 JMA_33670 JMA_33710 JMA_33710 JMA_33840 JMA_33840 JMA_34420 JMA_34420 JMA_34580 JMA_34580 JMA_35180 JMA_35180 JMA_35520 JMA_35520 JMA_36630 JMA_36630
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
secEPreprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (59 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1186 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1199 aa)
tufElongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (396 aa)
secYPreprotein translocase secY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (433 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (314 aa)
JMA_01810Hypothetical protein. (131 aa)
JMA_02190Thiol-disulfide oxidoreductase. (182 aa)
JMA_02540Monooxygenase. (432 aa)
JMA_03670Hypothetical protein. (407 aa)
JMA_03700Hypothetical protein. (401 aa)
JMA_03710Hypothetical protein. (192 aa)
katGCatalase/hydroperoxidase HPI(I); Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (736 aa)
JMA_04440Glutathione-binding protein gsiB precursor. (526 aa)
JMA_04660Putative peroxiredoxin. (168 aa)
JMA_05000Hypothetical protein; Belongs to the major facilitator superfamily. (492 aa)
JMA_05470Hypothetical protein. (413 aa)
JMA_05970ferredoxin--NADP reductase. (346 aa)
JMA_06370Hypothetical protein. (119 aa)
JMA_06380Superoxide dismutase-like protein yojM precursor. (51 aa)
JMA_06680Hypothetical protein. (377 aa)
JMA_07390Dipeptide-binding ABC transporter, periplasmic substrate-binding component. (546 aa)
JMA_07400Peptide ABC transporter permease. (334 aa)
JMA_07410Diguanylate cyclase. (298 aa)
JMA_07940Hypothetical protein. (314 aa)
JMA_07950Hypothetical protein. (296 aa)
JMA_08120Multidrug ABC transporter permease. (576 aa)
JMA_08460MFS transporter. (425 aa)
JMA_09040Branched-chain alpha-keto acid dehydrogenase subunit E2. (452 aa)
JMA_11680Multidrug MFS transporter; Belongs to the major facilitator superfamily. (476 aa)
JMA_11870ABC transporter. (576 aa)
JMA_11880Multidrug ABC transporter ATP-binding protein. (611 aa)
JMA_12410MFS transporter. (389 aa)
JMA_12640Multidrug ABC transporter ATP-binding protein. (581 aa)
JMA_12680Peroxiredoxin. (156 aa)
JMA_12930Thioredoxin. (157 aa)
JMA_13130Hypothetical protein; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (144 aa)
JMA_13190Multidrug ABC transporter ATP-binding protein. (585 aa)
JMA_13200Multidrug ABC transporter permease. (670 aa)
JMA_14050Oligopeptide-binding protein AppA precursor. (582 aa)
JMA_14060Peptide ABC transporter permease. (321 aa)
JMA_14070Peptide ABC transporter permease. (301 aa)
JMA_14180Globin. (132 aa)
JMA_15060MFS transporter. (497 aa)
JMA_15110Thioredoxin. (180 aa)
JMA_15120Multidrug ABC transporter ATP-binding protein. (584 aa)
JMA_15130Multidrug ABC transporter ATP-binding protein. (604 aa)
JMA_15230Branched-chain alpha-keto acid dehydrogenase subunit E2. (440 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (75 aa)
msrA-2Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (174 aa)
JMA_18720Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (422 aa)
JMA_189105-amino-6-(5-phosphoribosylamino)uracil reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (363 aa)
msrA-3methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (178 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (148 aa)
JMA_20090Hypothetical protein. (321 aa)
JMA_20250Peroxiredoxin. (184 aa)
JMA_20760Branched-chain alpha-keto acid dehydrogenase subunit E2. (429 aa)
JMA_21470Phosphate-binding protein. (322 aa)
JMA_21490Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (202 aa)
secDPreprotein translocase subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (756 aa)
JMA_23680Hypothetical protein. (315 aa)
JMA_23820Thioredoxin; Belongs to the thioredoxin family. (104 aa)
JMA_24380Metal-dependent hydrolase; Belongs to the UPF0173 family. (226 aa)
tpxLipid hydroperoxide peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (166 aa)
JMA_24940Hypothetical protein. (106 aa)
JMA_25260MFS transporter. (393 aa)
JMA_25290Hypothetical protein. (333 aa)
JMA_25790MFS transporter. (402 aa)
JMA_26010ferredoxin--NADP reductase. (331 aa)
JMA_26870Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (77 aa)
JMA_27580Thioredoxin reductase. (316 aa)
secAPreprotein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (835 aa)
JMA_30210Protein tyrosine phosphatase; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (150 aa)
JMA_31240Glutathione ABC transporter permease. (316 aa)
JMA_31250Glutathione transport system permease protein gsiD. (297 aa)
JMA_31260Glutathione-binding protein gsiB precursor. (544 aa)
JMA_31420Hypothetical protein. (459 aa)
arsCArsenate reductase; Catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)]. (139 aa)
JMA_31650Alkanesulfonate monooxygenase. (352 aa)
JMA_32840Membrane protein. (390 aa)
JMA_32960Diguanylate cyclase. (317 aa)
JMA_32970Peptide ABC transporter permease. (310 aa)
JMA_33480Multidrug ABC transporter ATP-binding protein. (572 aa)
JMA_33560Hypothetical protein. (431 aa)
JMA_33660Hypothetical protein. (602 aa)
JMA_33670Hypothetical protein. (142 aa)
JMA_33710Multidrug ABC transporter. (596 aa)
JMA_33840ABC transporter-like protein. (587 aa)
JMA_34420Hypothetical protein. (328 aa)
JMA_34580Hypothetical protein. (110 aa)
JMA_35180Hypothetical protein. (388 aa)
JMA_35520Hypothetical protein. (252 aa)
JMA_36630Peroxiredoxin. (198 aa)
Your Current Organism:
Jeotgalibacillus malaysiensis
NCBI taxonomy Id: 1508404
Other names: DSM 28777, J. malaysiensis, Jeotgalibacillus malaysiensis Yaakop et al. 2015, Jeotgalibacillus sp. D5, KCTC 33550, strain D5
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