Co-purification, co-crystallization, Yeast2Hybrid, Genetic Interactions, etc ... as imported from primary sources.
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Neighborhood
Groups of genes that are frequently observed in each other's genomic neighborhood.
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Databases
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
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Fusion
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANOM_006407
PKS_ER domain-containing protein. (528 aa)
ANOM_003947
Zinc-binding oxidoreductase CipB. (341 aa)
ANOM_003109
Polyketide synthase. (2615 aa)
ANOM_001446
Protein TOXD. (353 aa)
ANOM_000620
Zinc-binding oxidoreductase. (332 aa)
Your Current Organism:
Aspergillus nomius
NCBI taxonomy Id: 1509407 Other names: A. nomius NRRL 13137, Aspergillus nomius NRRL 13137, Aspergillus nomius NRRL13137