(161 nodes) Nucleolus network (Aspergillus nomius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANOM_011728	RNase3 domain protein. (354 aa)
	ANOM_011408	ATP-dependent RNA helicase mss116; Belongs to the DEAD box helicase family. (637 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
	ANOM_011525	SnoRNA binding protein. (997 aa)
	ANOM_010945	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (126 aa)
	ANOM_011289	Cell wall biogenesis protein phosphatase Ssd1. (1351 aa)
	ANOM_010947	Putative small nucleolar ribonucleoprotein complex subunit. (254 aa)
	ANOM_010406	66S preribosome component LOC1. (190 aa)
	ANOM_011235	Exosome complex exonuclease Rrp40. (272 aa)
	ANOM_009781	Uncharacterized protein. (1280 aa)
	ANOM_011467	90S preribosome component RRP12. (1261 aa)
	ANOM_011245	rRNA processing protein Nop9. (705 aa)
	ANOM_011180	rRNA biogenesis protein rrp36. (351 aa)
	ANOM_009616	Putative 60S ribosome biogenesis protein Rrp14. (526 aa)
	ANOM_010074	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (697 aa)
	ANOM_009569	Putative pre-rRNA processing protein Mrd1. (825 aa)
	ANOM_011224	DNA polymerase V. (986 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1068 aa)
	ANOM_010329	Exosome complex subunit Rrp46. (249 aa)
	ANOM_010027	Uncharacterized protein. (978 aa)
	ANOM_010410	U3 small nucleolar ribonucleoprotein IMP4. (299 aa)
	ANOM_010029	Uncharacterized protein. (120 aa)
	ANOM_009932	Ribosome biogenesis (Nop4). (692 aa)
	ANOM_009997	Ribosome biogenesis protein BMS1. (1145 aa)
	ANOM_010263	ATP-dependent RNA helicase mak5; Belongs to the DEAD box helicase family. (769 aa)
	ANOM_010823	3' exoribonuclease family protein. (417 aa)
	ANOM_006803	Putative nucleolus protein required for cell viability. (238 aa)
	ANOM_008278	CCAAT-box-binding transcription factor. (1109 aa)
	ANOM_008666	U3 small nucleolar RNA-associated protein 25; DEAD-box RNA helicase-like protein required for pre-18S rRNA processing, specifically at sites A0, A1, and A2. (705 aa)
	ANOM_009884	Uncharacterized protein. (396 aa)
	ANOM_009271	Putative small nucleolar ribonucleoprotein complex subunit. (238 aa)
	ANOM_009419	Putative pectate lyase. (234 aa)
	ANOM_010246	RNA processing factor 1. (411 aa)
	ANOM_009958	DEAH-box RNA helicase (Dhr1). (1218 aa)
	ANOM_009404	Exosome complex component rrp4. (389 aa)
	ANOM_009406	RNA binding protein Rnp24. (374 aa)
	ANOM_008446	Putative rRNA processing protein (Ebp2). (371 aa)
	ANOM_009086	Ribosome biogenesis protein Noc4. (550 aa)
	ANOM_008801	Uncharacterized protein. (408 aa)
	ANOM_009555	Exosome complex endonuclease 2/ribosomal RNA processing protein. (292 aa)
	ANOM_009235	Putative rRNA maturation protein (Nop14). (912 aa)
	ANOM_007582	Uncharacterized protein. (283 aa)
	ANOM_008264	Putative U3 small nucleolar ribonucleoprotein subunit (Imp3). (188 aa)
	ANOM_008809	Ribosome biogenesis protein Kri1. (589 aa)
	ANOM_007737	Putative ATP dependent RNA helicase (Dob1). (1080 aa)
	ANOM_007827	rRNA processing protein gar2. (474 aa)
	ANOM_009481	WD repeat protein. (721 aa)
	ANOM_008558	HEAT repeat protein (DRIM). (2585 aa)
	ANOM_010559	Putative small nucleolar ribonucleoprotein complex subunit. (951 aa)
	ANOM_007195	Translation machinery-associated protein. (178 aa)
	ANOM_009452	ATP-dependent RNA helicase drs1; Belongs to the DEAD box helicase family. (583 aa)
	ERB1	Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (784 aa)
	ANOM_008306	3' exoribonuclease family protein (Rrp42). (386 aa)
	ANOM_007171	Putative small nucleolar ribonucleoprotein complex subunit. (979 aa)
	ANOM_007167	rRNA processing protein RRP9. (621 aa)
	ANOM_008378	rRNA-processing protein; Involved in nucleolar integrity and required for processing of the pre-rRNA for the 60S ribosome subunit. Belongs to the CGR1 family. (117 aa)
	ANOM_006264	Putative C2H2 finger domain protein. (111 aa)
	ANOM_008175	Ribosome biogenesis protein NSA2. (256 aa)
	ANOM_007275	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family. (293 aa)
	ANOM_006120	ATP-dependent rRNA helicase RRP3; Belongs to the DEAD box helicase family. (472 aa)
	ANOM_006121	Ribosome biogenesis protein Ssf2. (428 aa)
	ANOM_005549	rRNA processing protein Bystin. (496 aa)
	SPB1	AdoMet-dependent rRNA methyltransferase SPB1; Required for proper assembly of pre-ribosomal particles during the biogenesis of the 60S ribosomal subunit; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (802 aa)
	ANOM_006129	Small nucleolar ribonucleoprotein complex subunit (SOF1). (448 aa)
	ANOM_006117	HNRNP arginine N-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (353 aa)
	ANOM_006353	Essential for mitotic growth 1. (260 aa)
	ANOM_006326	Serine/threonine-protein kinase rio2. (405 aa)
	ANOM_005966	Protein bfr2. (558 aa)
	ANOM_005868	ATP-dependent RNA helicase dbp3; Belongs to the DEAD box helicase family. (497 aa)
	ANOM_006533	zf-LYAR domain-containing protein. (508 aa)
	ANOM_006209	Nucleolar protein nop5. (578 aa)
	ANOM_006219	RNA helicase. (637 aa)
	ANOM_007502	RNA helicase. (596 aa)
	ANOM_003661	Exosome-associated protein. (224 aa)
	ANOM_003675	RNA binding protein. (328 aa)
	ANOM_005737	Putative phosphoenolpyruvate phosphomutase. (395 aa)
	ANOM_003981	Dual specificity phosphatase. (342 aa)
	ANOM_006082	Nonsense-mediated mRNA decay protein (Nmd5). (1070 aa)
	ANOM_006012	Protein PUF6. (708 aa)
	ANOM_005406	Putative small nucleolar ribonucleoprotein complex component (Utp5). (844 aa)
	ANOM_006024	GTP-binding protein. (533 aa)
	ANOM_004872	Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (220 aa)
	ANOM_005478	66S preribosome component NOP16. (240 aa)
	ANOM_005815	Pre-rRNA-processing protein pno1. (319 aa)
	ANOM_004850	Protein required for cell viability Rrp17. (216 aa)
	ANOM_004520	Nuclear protein (Sgd1). (855 aa)
	ANOM_004971	Ribosomal RNA processing protein. (312 aa)
	ANOM_005812	Methyltransferase BUD23. (279 aa)
	ANOM_004983	Sas10/Utp3 family protein. (648 aa)
	ANOM_005510	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (559 aa)
	ANOM_005260	KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (361 aa)
	ANOM_005129	ATP-dependent RNA helicase dbp8; Belongs to the DEAD box helicase family. (523 aa)
	ANOM_004365	Exosome complex exonuclease DIS3; Belongs to the RNR ribonuclease family. (1043 aa)
	ANOM_004745	rRNA processing protein. (313 aa)
	ANOM_004934	PINc domain-containing protein. (333 aa)
	ANOM_004736	Putative small nucleolar ribonucleoprotein complex subunit Dip2. (929 aa)
	ANOM_005019	Nucleolar GTP-binding protein 1. (658 aa)
	ANOM_004747	Putative rRNA processing protein Pwp1. (536 aa)
	ANOM_004481	Brix domain-containing protein. (727 aa)
	ANOM_004498	WD repeat-containing protein. (515 aa)
	ANOM_003945	Exosome complex subunit Csl4. (226 aa)
	ANOM_004692	Putative C2H2 finger domain protein. (450 aa)
	ANOM_004066	U3 small nucleolar RNA-associated protein 10. (1823 aa)
	ANOM_004181	Putative ATP dependent RNA helicase (Dbp7); Belongs to the DEAD box helicase family. (761 aa)
	ANOM_004051	U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (287 aa)
	ANOM_003939	Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (227 aa)
	ANOM_004418	Putative ribosome assembly protein Noc2. (779 aa)
	ANOM_004466	Uncharacterized protein. (528 aa)
	ANOM_004322	Putative small nucleolar ribonucleoprotein complex subunit Utp14. (967 aa)
	ANOM_004551	Exosome complex endonuclease 1. (269 aa)
	ANOM_003870	Nucleolar protein 12. (511 aa)
	ANOM_003357	Putative williams-beuren syndrome chromosome region. (216 aa)
	ANOM_004422	ATP-dependent RNA helicase rok1. (727 aa)
	ANOM_004248	Ribosome biogenesis protein. (331 aa)
	ANOM_002508	Putative methyltransferase (Ncl1); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (868 aa)
	ANOM_003318	Putative pre-rRNA processing protein Esf1. (731 aa)
	ANOM_004291	Nucleolar protein 56. (522 aa)
	ANOM_003026	U3 small nucleolar RNA-associated protein 22. (1110 aa)
	ANOM_003329	Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (390 aa)
	ANOM_004310	rRNA processing protein Utp6. (395 aa)
	ANOM_003467	Pre-rRNA processing protein Tsr1. (815 aa)
	ANOM_003510	ATP-dependent RNA helicase drs1. (219 aa)
	ANOM_003516	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (753 aa)
	ANOM_002518	rRNA methyltransferase NOP1. (317 aa)
	ANOM_003114	Small nucleolar ribonucleoprotein complex subunit Utp15. (541 aa)
	ANOM_003284	rRNA biogenesis protein RRP5. (1824 aa)
	ANOM_002736	20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (419 aa)
	ANOM_002467	Casein kinase I hhp1; Belongs to the protein kinase superfamily. (410 aa)
	ANOM_002743	rRNA processing protein RRP15. (301 aa)
	ANOM_003466	U3 small nucleolar RNA-associated protein 7. (536 aa)
	ANOM_002414	ATP-dependent RNA helicase MSS116. (556 aa)
	ANOM_002447	Ribosome biogenesis protein RLP24. (188 aa)
	ANOM_002980	BNR/Asp-box repeat domain protein. (360 aa)
	ANOM_002609	Ribosome assembly protein rrb1. (496 aa)
	ANOM_003462	Putative RNA 3'-terminal phosphate cyclase. (498 aa)
	ANOM_002259	Uncharacterized protein. (1359 aa)
	ANOM_001897	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (185 aa)
	ANOM_001898	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family. (686 aa)
	ANOM_001922	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (500 aa)
	ANOM_003187	ATP-dependent RNA helicase DBP10. (908 aa)
	ANOM_001921	Pre-rRNA-processing protein esf2. (329 aa)
	ANOM_001916	Curved DNA-binding protein. (383 aa)
	ANOM_003191	RNA helicase. (797 aa)
	ANOM_001984	U3 small nucleolar ribonucleoprotein Lcp5. (383 aa)
	ANOM_001378	Protein MAK16; Belongs to the MAK16 family. (323 aa)
	ANOM_002021	Periodic tryptophan protein 2. (900 aa)
	ANOM_001814	RRP7 superfamily domain-containing protein. (310 aa)
	ANOM_001795	Conserved glycine-rich protein. (252 aa)
	ANOM_001785	WD domain protein. (931 aa)
	ANOM_001554	RNA-3'-phosphate cyclase family protein. (402 aa)
	NOP7	Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (679 aa)
	YTM1	Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (487 aa)
	ANOM_000940	Putative phosphoenolpyruvate phosphomutase. (474 aa)
	ANOM_000972	Uncharacterized protein. (1604 aa)
	ANOM_000565	Carbonic anhydrase. (271 aa)
	ANOM_000918	60S ribosome biogenesis protein Mak11. (427 aa)
	ANOM_000663	Low-temperature viability protein ltv1. (443 aa)
	ANOM_000662	Putative ribosome biogenesis GTPase Lsg1. (638 aa)
	ANOM_000107	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (752 aa)
	ANOM_000262	ATP-dependent RNA helicase dbp9. (637 aa)
	ANOM_000231	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (567 aa)

Your Current Organism:

Aspergillus nomius

NCBI taxonomy Id: 1509407
Other names: A. nomius NRRL 13137, Aspergillus nomius NRRL 13137, Aspergillus nomius NRRL13137

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOM_000107	ANOM_000231	A0A0L1JIG9	A0A0L1JIX5	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.	0.528
ANOM_000107	ANOM_000262	A0A0L1JIG9	A0A0L1JIL4	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	ATP-dependent RNA helicase dbp9.	0.923
ANOM_000107	ANOM_000565	A0A0L1JIG9	A0A0L1JH63	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Carbonic anhydrase.	0.863
ANOM_000107	ANOM_000662	A0A0L1JIG9	A0A0L1JHZ5	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Putative ribosome biogenesis GTPase Lsg1.	0.935
ANOM_000107	ANOM_000663	A0A0L1JIG9	A0A0L1JHY5	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Low-temperature viability protein ltv1.	0.890
ANOM_000107	ANOM_000918	A0A0L1JIG9	A0A0L1JHF7	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	60S ribosome biogenesis protein Mak11.	0.870
ANOM_000107	ANOM_000972	A0A0L1JIG9	A0A0L1JGL4	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.535
ANOM_000107	ANOM_001378	A0A0L1JIG9	A0A0L1JEA4	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Protein MAK16; Belongs to the MAK16 family.	0.981
ANOM_000107	ANOM_001554	A0A0L1JIG9	A0A0L1JFV0	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	RNA-3'-phosphate cyclase family protein.	0.789
ANOM_000107	ANOM_001785	A0A0L1JIG9	A0A0L1JEZ8	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	WD domain protein.	0.872
ANOM_000107	ANOM_001795	A0A0L1JIG9	A0A0L1JEW6	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Conserved glycine-rich protein.	0.943
ANOM_000107	ANOM_001814	A0A0L1JIG9	A0A0L1JEM7	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	RRP7 superfamily domain-containing protein.	0.538
ANOM_000107	ANOM_001897	A0A0L1JIG9	A0A0L1JCN6	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	60S ribosome subunit biogenesis protein NIP7; Required for proper 27S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family.	0.997
ANOM_000107	ANOM_001898	A0A0L1JIG9	A0A0L1JCP0	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Nucleolar complex-associated protein 3; Required for synthesis of 60S ribosomal subunits and the transport of pre-ribosomes from the nucleoplasm to the cytoplasm. Belongs to the CBF/MAK21 family.	0.992
ANOM_000107	ANOM_001916	A0A0L1JIG9	A0A0L1JCU2	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Curved DNA-binding protein.	0.827
ANOM_000107	ANOM_001921	A0A0L1JIG9	A0A0L1JCT8	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Pre-rRNA-processing protein esf2.	0.482
ANOM_000107	ANOM_001922	A0A0L1JIG9	A0A0L1JCS0	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.826
ANOM_000107	ANOM_001984	A0A0L1JIG9	A0A0L1JDF5	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	U3 small nucleolar ribonucleoprotein Lcp5.	0.840
ANOM_000107	ANOM_002021	A0A0L1JIG9	A0A0L1JEJ9	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Periodic tryptophan protein 2.	0.911
ANOM_000107	ANOM_002259	A0A0L1JIG9	A0A0L1JCM3	S-adenosylmethionine-dependent methyltransferase superfamily domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.	Uncharacterized protein.	0.724