STRINGSTRING
ANOM_011826 ANOM_011826 ANOM_011754 ANOM_011754 ANOM_010913 ANOM_010913 ANOM_011295 ANOM_011295 ANOM_011024 ANOM_011024 ANOM_010957 ANOM_010957 ANOM_010906 ANOM_010906 ANOM_010956 ANOM_010956 ANOM_010113 ANOM_010113 ANOM_010711 ANOM_010711 ANOM_010705 ANOM_010705 ANOM_010589 ANOM_010589 ANOM_011199 ANOM_011199 ANOM_010864 ANOM_010864 ANOM_010851 ANOM_010851 ANOM_010522 ANOM_010522 ANOM_009392 ANOM_009392 ANOM_010026 ANOM_010026 ANOM_008283 ANOM_008283 ANOM_009882 ANOM_009882 ANOM_009103 ANOM_009103 ANOM_010431 ANOM_010431 ANOM_008985 ANOM_008985 ANOM_009237 ANOM_009237 ANOM_008150 ANOM_008150 ANOM_007441 ANOM_007441 ANOM_008539 ANOM_008539 ANOM_007730 ANOM_007730 ANOM_008561 ANOM_008561 ANOM_007196 ANOM_007196 ANOM_007193 ANOM_007193 ANOM_010556 ANOM_010556 ANOM_006664 ANOM_006664 ANOM_008616 ANOM_008616 ANOM_008372 ANOM_008372 ANOM_007766 ANOM_007766 ANOM_008615 ANOM_008615 ANOM_007560 ANOM_007560 ANOM_008014 ANOM_008014 ANOM_008305 ANOM_008305 ANOM_007605 ANOM_007605 ANOM_006922 ANOM_006922 ANOM_007975 ANOM_007975 ANOM_008167 ANOM_008167 ANOM_008047 ANOM_008047 ANOM_006853 ANOM_006853 ANOM_006855 ANOM_006855 ANOM_006415 ANOM_006415 ANOM_007094 ANOM_007094 ANOM_007807 ANOM_007807 FEN1 FEN1 ANOM_006340 ANOM_006340 ANOM_007180 ANOM_007180 ANOM_006323 ANOM_006323 ANOM_005857 ANOM_005857 ANOM_007105 ANOM_007105 ANOM_005147 ANOM_005147 ANOM_005870 ANOM_005870 ANOM_006641 ANOM_006641 ANOM_006221 ANOM_006221 ANOM_005392 ANOM_005392 ANOM_005395 ANOM_005395 ANOM_003982 ANOM_003982 ANOM_006023 ANOM_006023 ANOM_005411 ANOM_005411 ANOM_006008 ANOM_006008 ANOM_003995 ANOM_003995 MCM7 MCM7 ANOM_005412 ANOM_005412 ANOM_004859 ANOM_004859 ANOM_005318 ANOM_005318 ANOM_004855 ANOM_004855 ANOM_004528 ANOM_004528 ANOM_004704 ANOM_004704 ANOM_004984 ANOM_004984 ANOM_005048 ANOM_005048 ANOM_005634 ANOM_005634 ANOM_004362 ANOM_004362 ANOM_004370 ANOM_004370 ANOM_004497 ANOM_004497 ANOM_004496 ANOM_004496 ANOM_003795 ANOM_003795 ANOM_004395 ANOM_004395 ANOM_003927 ANOM_003927 ANOM_004565 ANOM_004565 ANOM_003031 ANOM_003031 ANOM_004237 ANOM_004237 ANOM_004288 ANOM_004288 ANOM_003340 ANOM_003340 ANOM_003602 ANOM_003602 ANOM_003544 ANOM_003544 ANOM_003577 ANOM_003577 ANOM_003301 ANOM_003301 ANOM_002733 ANOM_002733 ANOM_002452 ANOM_002452 ANOM_002600 ANOM_002600 ANOM_003296 ANOM_003296 ANOM_002568 ANOM_002568 ANOM_001943 ANOM_001943 ANOM_001926 ANOM_001926 ANOM_003186 ANOM_003186 ANOM_002238 ANOM_002238 ANOM_002242 ANOM_002242 ANOM_001151 ANOM_001151 ANOM_001196 ANOM_001196 ANOM_001383 ANOM_001383 ANOM_001049 ANOM_001049 ANOM_001022 ANOM_001022 SLX1 SLX1 ANOM_001815 ANOM_001815 ANOM_000878 ANOM_000878 ANOM_000117 ANOM_000117
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANOM_011826DNA polymerase iota. (615 aa)
ANOM_011754DNA mismatch repair protein (Mlh3). (929 aa)
ANOM_010913Uncharacterized protein. (660 aa)
ANOM_011295DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (651 aa)
ANOM_011024Uncharacterized protein. (983 aa)
ANOM_010957Proliferating cell nuclear antigen. (618 aa)
ANOM_010906Origin recognition complex subunit 2. (552 aa)
ANOM_010956Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (269 aa)
ANOM_010113DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (500 aa)
ANOM_010711Origin recognition complex subunit Orc4. (653 aa)
ANOM_010705DNA replication complex GINS protein psf1. (237 aa)
ANOM_010589DNA mismatch repair protein msh-2; Component of the post-replicative DNA mismatch repair system (MMR). (940 aa)
ANOM_011199Putative DNA repair protein (Rad57). (547 aa)
ANOM_010864Putative sister chromatid cohesion protein (Eso1). (673 aa)
ANOM_010851Chromosome segregation protein (SepB). (838 aa)
ANOM_010522AAA domain-containing protein. (1197 aa)
ANOM_009392BRCT domain-containing protein. (172 aa)
ANOM_010026DNA polymerase. (1462 aa)
ANOM_008283Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (781 aa)
ANOM_009882Chromosome transmission fidelity protein 18. (1053 aa)
ANOM_009103Topoisomerase 1-associated factor 1. (1164 aa)
ANOM_010431DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1132 aa)
ANOM_008985SAE2 domain-containing protein. (721 aa)
ANOM_009237Origin recognition complex subunit. (695 aa)
ANOM_008150DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1202 aa)
ANOM_007441RecQ family helicase MusN. (1525 aa)
ANOM_008539ATP-dependent DNA helicase mph1. (1128 aa)
ANOM_007730Uncharacterized protein. (1218 aa)
ANOM_008561GINS DNA replication complex subunit Sld5. (254 aa)
ANOM_007196Exonuclease. (731 aa)
ANOM_007193DNA primase; Belongs to the eukaryotic-type primase small subunit family. (526 aa)
ANOM_010556ATP-dependent DNA helicase. (998 aa)
ANOM_006664DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (269 aa)
ANOM_008616DNA replication complex GINS protein psf3. (178 aa)
ANOM_008372ELMO domain-containing protein. (1503 aa)
ANOM_007766DNA-directed polymerase kappa. (604 aa)
ANOM_008615Cnn_1N domain-containing protein. (973 aa)
ANOM_007560Putative DNA repair protein Mus81. (582 aa)
ANOM_008014DNA ligase. (823 aa)
ANOM_008305Meiosis induction protein kinase (Ime2). (772 aa)
ANOM_007605Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (786 aa)
ANOM_006922DNA polymerase. (1705 aa)
ANOM_007975EthD domain-containing protein. (157 aa)
ANOM_008167Uncharacterized protein. (307 aa)
ANOM_008047EthD domain-containing protein. (155 aa)
ANOM_006853Replication factor C subunit 5. (362 aa)
ANOM_006855Replication factor C subunit 1. (1079 aa)
ANOM_006415DNA mismatch repair protein. (858 aa)
ANOM_007094DNA replication protein. (775 aa)
ANOM_007807DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1155 aa)
FEN1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (411 aa)
ANOM_006340Putative DNA lyase. (632 aa)
ANOM_007180Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2895 aa)
ANOM_006323DNA mismatch repair protein Mlh1. (737 aa)
ANOM_005857DNA polymerase epsilon subunit B. (751 aa)
ANOM_007105Uncharacterized protein. (715 aa)
ANOM_005147Putative G1/S regulator NimO. (669 aa)
ANOM_005870Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (606 aa)
ANOM_006641Rad51 family DNA repair protein. (453 aa)
ANOM_006221Rad2-like endonuclease. (878 aa)
ANOM_005392Chromosome segregation in meiosis protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (284 aa)
ANOM_005395Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family. (2465 aa)
ANOM_003982Uncharacterized protein. (208 aa)
ANOM_006023CBF/NF-Y family transcription factor. (318 aa)
ANOM_005411Sister chromatid cohesion protein Ctf8. (155 aa)
ANOM_006008DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (348 aa)
ANOM_003995UBA domain-containing protein. (895 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (810 aa)
ANOM_005412Uncharacterized protein. (196 aa)
ANOM_004859Cell division control protein; Belongs to the CDC6/cdc18 family. (652 aa)
ANOM_005318Replication factor C subunit 4. (344 aa)
ANOM_004855Putative 3-5 exonuclease. (434 aa)
ANOM_004528MRC1 domain-containing protein. (1283 aa)
ANOM_004704DNA mismatch repair protein (Pms1). (1084 aa)
ANOM_004984DNA mismatch repair protein Msh5. (850 aa)
ANOM_005048RECA_2 domain-containing protein. (375 aa)
ANOM_005634DNA helicase; Belongs to the MCM family. (952 aa)
ANOM_004362DNA replication helicase Dna2. (1666 aa)
ANOM_004370BRCT domain protein. (852 aa)
ANOM_004497DNA mismatch repair protein Msh4. (609 aa)
ANOM_004496Putative DNA mismatch repair protein Msh4. (258 aa)
ANOM_003795DNA helicase; Belongs to the MCM family. (887 aa)
ANOM_004395Uncharacterized protein. (320 aa)
ANOM_003927Subunit of DNA polymerase II. (800 aa)
ANOM_004565Putative serine/threonine protein kinase; Belongs to the protein kinase superfamily. (375 aa)
ANOM_003031Serine/threonine protein kinase. (490 aa)
ANOM_004237DNA mismatch repair protein Msh1. (1075 aa)
ANOM_004288DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2223 aa)
ANOM_003340Asparaginyl-tRNA synthetase, cytoplasmic. (582 aa)
ANOM_003602DNA helicase; Belongs to the MCM family. (705 aa)
ANOM_003544Putative cell division control protein 45. (860 aa)
ANOM_003577Putative cytochrome P450; Belongs to the cytochrome P450 family. (465 aa)
ANOM_003301Mitotic spindle checkpoint protein (Mad2B). (294 aa)
ANOM_002733Putative DNA damage repair protein (Rad9). (1415 aa)
ANOM_002452DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
ANOM_002600Uncharacterized protein. (455 aa)
ANOM_003296Sister chromatid cohesion protein Dcc1. (370 aa)
ANOM_002568DNA helicase; Belongs to the MCM family. (893 aa)
ANOM_001943DNA polymerase. (1113 aa)
ANOM_001926Uncharacterized protein. (444 aa)
ANOM_003186Putative replication factor-a protein. (275 aa)
ANOM_002238DNA ligase. (962 aa)
ANOM_002242DNA helicase; Belongs to the MCM family. (1007 aa)
ANOM_001151Replication factor C subunit 2. (390 aa)
ANOM_001196Putative RecQ-mediated genome instability protein. (151 aa)
ANOM_001383Checkpoint protein; Belongs to the HUS1 family. (356 aa)
ANOM_001049DNA repair protein Rad1. (387 aa)
ANOM_001022DNA repair protein Rad50. (1399 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (398 aa)
ANOM_001815Meiotic recombination protein DMC1; Belongs to the RecA family. (337 aa)
ANOM_000878DNA polymerase delta subunit 2. (510 aa)
ANOM_000117Replication factor C subunit 3. (399 aa)
Your Current Organism:
Aspergillus nomius
NCBI taxonomy Id: 1509407
Other names: A. nomius NRRL 13137, Aspergillus nomius NRRL 13137, Aspergillus nomius NRRL13137
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