(5 nodes) Sensing of DNA Double Strand Breaks, and FATC domain network (Aspergillus nomius)

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Your Input:
	ANOM_007605	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (786 aa)
	ANOM_007975	EthD domain-containing protein. (157 aa)
	ANOM_007180	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily. (2895 aa)
	ANOM_005395	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family. (2465 aa)
	ANOM_001022	DNA repair protein Rad50. (1399 aa)

Your Current Organism:

Aspergillus nomius

NCBI taxonomy Id: 1509407
Other names: A. nomius NRRL 13137, Aspergillus nomius NRRL 13137, Aspergillus nomius NRRL13137

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOM_001022	ANOM_005395	A0A0L1JFB6	A0A0L1J200	DNA repair protein Rad50.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.963
ANOM_001022	ANOM_007180	A0A0L1JFB6	A0A0L1J0H5	DNA repair protein Rad50.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.986
ANOM_001022	ANOM_007605	A0A0L1JFB6	A0A0L1IY69	DNA repair protein Rad50.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.999
ANOM_001022	ANOM_007975	A0A0L1JFB6	A0A0L1IYF1	DNA repair protein Rad50.	EthD domain-containing protein.	0.876
ANOM_005395	ANOM_001022	A0A0L1J200	A0A0L1JFB6	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	DNA repair protein Rad50.	0.963
ANOM_005395	ANOM_007180	A0A0L1J200	A0A0L1J0H5	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.997
ANOM_005395	ANOM_007605	A0A0L1J200	A0A0L1IY69	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.982
ANOM_005395	ANOM_007975	A0A0L1J200	A0A0L1IYF1	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	EthD domain-containing protein.	0.924
ANOM_007180	ANOM_001022	A0A0L1J0H5	A0A0L1JFB6	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	DNA repair protein Rad50.	0.986
ANOM_007180	ANOM_005395	A0A0L1J0H5	A0A0L1J200	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.997
ANOM_007180	ANOM_007605	A0A0L1J0H5	A0A0L1IY69	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.989
ANOM_007180	ANOM_007975	A0A0L1J0H5	A0A0L1IYF1	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	EthD domain-containing protein.	0.884
ANOM_007605	ANOM_001022	A0A0L1IY69	A0A0L1JFB6	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	DNA repair protein Rad50.	0.999
ANOM_007605	ANOM_005395	A0A0L1IY69	A0A0L1J200	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.982
ANOM_007605	ANOM_007180	A0A0L1IY69	A0A0L1J0H5	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.989
ANOM_007605	ANOM_007975	A0A0L1IY69	A0A0L1IYF1	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	EthD domain-containing protein.	0.928
ANOM_007975	ANOM_001022	A0A0L1IYF1	A0A0L1JFB6	EthD domain-containing protein.	DNA repair protein Rad50.	0.876
ANOM_007975	ANOM_005395	A0A0L1IYF1	A0A0L1J200	EthD domain-containing protein.	Phosphatidylinositol 3-and 4-kinase; Belongs to the PI3/PI4-kinase family.	0.924
ANOM_007975	ANOM_007180	A0A0L1IYF1	A0A0L1J0H5	EthD domain-containing protein.	Serine/threonine-protein kinase Tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability; Belongs to the PI3/PI4-kinase family. ATM subfamily.	0.884
ANOM_007975	ANOM_007605	A0A0L1IYF1	A0A0L1IY69	EthD domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.928