(12 nodes) Protein insertion into ER membrane network (Aspergillus nomius)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	ANOM_011723	Uncharacterized protein. (328 aa)
	ANOM_011279	DUF2012 domain-containing protein. (271 aa)
	ANOM_010348	Zn(2)-C6 fungal-type domain-containing protein. (485 aa)
	ANOM_010547	Uncharacterized protein. (333 aa)
	ANOM_007828	Protein GET1. (211 aa)
	ANOM_007750	Zn(2)-C6 fungal-type domain-containing protein. (520 aa)
	ANOM_006991	Uncharacterized protein. (118 aa)
	ANOM_006706	Zn(2)-C6 fungal-type domain-containing protein. (499 aa)
	ANOM_006053	Uncharacterized protein. (277 aa)
	ANOM_005320	Uncharacterized protein. (346 aa)
	GET3	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (330 aa)
	ANOM_001740	C6 zinc finger domain protein. (513 aa)

Your Current Organism:

Aspergillus nomius

NCBI taxonomy Id: 1509407
Other names: A. nomius NRRL 13137, Aspergillus nomius NRRL 13137, Aspergillus nomius NRRL13137

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOM_001740	ANOM_007828	A0A0L1JDL5	A0A0L1IVA4	C6 zinc finger domain protein.	Protein GET1.	0.668
ANOM_001740	GET3	A0A0L1JDL5	A0A0L1J2V1	C6 zinc finger domain protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.543
ANOM_005320	ANOM_006706	A0A0L1J264	A0A0L1J047	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.481
ANOM_005320	ANOM_007828	A0A0L1J264	A0A0L1IVA4	Uncharacterized protein.	Protein GET1.	0.676
ANOM_005320	ANOM_010348	A0A0L1J264	A0A0L1IPR6	Uncharacterized protein.	Zn(2)-C6 fungal-type domain-containing protein.	0.481
ANOM_005320	ANOM_011723	A0A0L1J264	A0A0L1IKY6	Uncharacterized protein.	Uncharacterized protein.	0.481
ANOM_005320	GET3	A0A0L1J264	A0A0L1J2V1	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.990
ANOM_006053	ANOM_007828	A0A0L1J0I0	A0A0L1IVA4	Uncharacterized protein.	Protein GET1.	0.552
ANOM_006053	ANOM_011279	A0A0L1J0I0	A0A0L1ILS6	Uncharacterized protein.	DUF2012 domain-containing protein.	0.972
ANOM_006053	GET3	A0A0L1J0I0	A0A0L1J2V1	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.527
ANOM_006706	ANOM_005320	A0A0L1J047	A0A0L1J264	Zn(2)-C6 fungal-type domain-containing protein.	Uncharacterized protein.	0.481
ANOM_006706	ANOM_007828	A0A0L1J047	A0A0L1IVA4	Zn(2)-C6 fungal-type domain-containing protein.	Protein GET1.	0.899
ANOM_006706	GET3	A0A0L1J047	A0A0L1J2V1	Zn(2)-C6 fungal-type domain-containing protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.907
ANOM_006991	ANOM_007828	A0A0L1IZ50	A0A0L1IVA4	Uncharacterized protein.	Protein GET1.	0.668
ANOM_006991	GET3	A0A0L1IZ50	A0A0L1J2V1	Uncharacterized protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.543
ANOM_007750	ANOM_007828	A0A0L1IWI1	A0A0L1IVA4	Zn(2)-C6 fungal-type domain-containing protein.	Protein GET1.	0.668
ANOM_007750	GET3	A0A0L1IWI1	A0A0L1J2V1	Zn(2)-C6 fungal-type domain-containing protein.	ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...]	0.543
ANOM_007828	ANOM_001740	A0A0L1IVA4	A0A0L1JDL5	Protein GET1.	C6 zinc finger domain protein.	0.668
ANOM_007828	ANOM_005320	A0A0L1IVA4	A0A0L1J264	Protein GET1.	Uncharacterized protein.	0.676
ANOM_007828	ANOM_006053	A0A0L1IVA4	A0A0L1J0I0	Protein GET1.	Uncharacterized protein.	0.552