(129 nodes) Positive regulation of transcription by RNA polymerase II network (Aspergillus nomius)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANOM_001787	Putative cell cycle control protein TINC. (694 aa)
	ANOM_001810	Putative cAMP-dependent protein kinase pathway protein (Som1). (788 aa)
	ANOM_002028	Protein kinase domain-containing protein. (1052 aa)
	ANOM_001710	Beta-lactamase domain-containing protein. (157 aa)
	ANOM_001179	Multiprotein-bridging factor 1. (195 aa)
	ANOM_001001	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (764 aa)
	ANOM_000633	DNA helicase ino80. (1651 aa)
	ANOM_000640	Chromatin structure-remodeling complex subunit snf2. (1447 aa)
	ANOM_000740	Negative cofactor 2 complex subunit beta. (165 aa)
	ANOM_000474	C6 transcription factor. (381 aa)
	ANOM_000135	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (792 aa)
	ANOM_000287	Uncharacterized protein. (438 aa)
	ANOM_000175	Uncharacterized protein. (374 aa)
	ANOM_000476	Uncharacterized protein. (361 aa)
	ANOM_001592	Uncharacterized protein. (677 aa)
	ANOM_001166	SRF-type transcription factor RlmA. (610 aa)
	ANOM_001709	Beta-lactamase family protein. (196 aa)
	ANOM_001992	C6 transcription factor. (388 aa)
	ANOM_003183	Putative C2H2 finger domain protein (Ezf). (408 aa)
	ANOM_001613	Esterase. (366 aa)
	ANOM_002536	APSES transcription factor. (691 aa)
	ANOM_002740	BZIP transcription factor (HapX). (544 aa)
	ANOM_002587	Uncharacterized protein. (324 aa)
	ANOM_002733	Putative DNA damage repair protein (Rad9). (1415 aa)
	ANOM_002752	Putative lipase. (337 aa)
	ANOM_003464	Protein PtaB. (503 aa)
	ANOM_003068	Esterase. (342 aa)
	ANOM_003087	Putative C6 transcription factor. (882 aa)
	ANOM_003071	Uncharacterized protein. (531 aa)
	ANOM_003355	Beta-lactamase family protein. (409 aa)
	ANOM_003353	C6 transcription factor. (834 aa)
	ANOM_004991	Putative RING finger domain protein (Rnf10). (731 aa)
	ANOM_002922	Beta-lactamase family protein. (401 aa)
	ANOM_003852	Putative AAA family ATPase. (1988 aa)
	ANOM_004612	Uncharacterized protein. (512 aa)
	ANOM_005011	Zn(2)-C6 fungal-type domain-containing protein. (723 aa)
	ANOM_004411	NDT80 / PhoG like DNA-binding family protein. (656 aa)
	ANOM_003789	Nuclear transcription factor Y subunit B-3. (215 aa)
	ANOM_003921	C6 transcription factor. (1032 aa)
	ANOM_005906	HTH CENPB-type domain-containing protein. (206 aa)
	ANOM_004949	Uncharacterized protein. (639 aa)
	ANOM_003552	26S protease subunit rpt4; Belongs to the AAA ATPase family. (393 aa)
	ANOM_011865	BZIP transcription factor. (276 aa)
	ANOM_011312	MYB DNA-binding domain protein. (636 aa)
	ANOM_011784	C2H2 transcription factor (Azf1). (450 aa)
	ANOM_011699	Stress response regulator/HFS transcription factor. (631 aa)
	ANOM_006719	Forkhead transcription factor Fkh1/2. (700 aa)
	ANOM_005955	Glutaminase. (665 aa)
	ANOM_007062	Uncharacterized protein. (149 aa)
	ANOM_006720	pH-response transcription factor pacC/RIM101. (662 aa)
	ANOM_005742	PX domain protein. (1146 aa)
	ANOM_006061	C6 transcription factor. (1097 aa)
	ANOM_006197	NTP binding protein. (269 aa)
	ANOM_006184	Forkhead box protein L2. (701 aa)
	ANOM_005548	BZIP transcription factor HacA. (441 aa)
	ANOM_006621	ISWI chromatin-remodeling complex ATPase ISW2. (1109 aa)
	ANOM_006420	Putative serine/threonine protein kinase. (1127 aa)
	ANOM_007475	CP2 transcription factor. (671 aa)
	ANOM_007646	Putative membrane-tethered transcription factor (SPT23). (1411 aa)
	ANOM_006114	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (462 aa)
	ANOM_006178	Uncharacterized protein. (408 aa)
	ANOM_006851	HLH transcription factor. (446 aa)
	ANOM_006949	RNA polymerase-associated protein LEO1. (466 aa)
	ANOM_006882	Putative C2H2 transcription factor Crz1. (760 aa)
	ANOM_008017	CP2 transcription factor. (768 aa)
	ANOM_008595	WD_REPEATS_REGION domain-containing protein. (400 aa)
	ANOM_006391	C6 transcription factor NosA. (689 aa)
	ANOM_004380	Cell differentiation protein RCD1. (393 aa)
	ANOM_005043	SAP30_Sin3_bdg domain-containing protein. (243 aa)
	ANOM_004645	Quinic acid utilization activator. (932 aa)
	ANOM_004714	Abhydrolase_3 domain-containing protein. (423 aa)
	ANOM_003844	Putative C6 finger domain protein. (755 aa)
	ANOM_004529	RNA polymerase II transcription elongation factor Rtf1p. (439 aa)
	ANOM_005595	Uncharacterized protein. (257 aa)
	ANOM_006240	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (415 aa)
	ANOM_004707	Putative GATA transcription factor (AreB). (510 aa)
	ANOM_005513	Uncharacterized protein. (580 aa)
	ANOM_005383	26S protease subunit rpt4; Belongs to the AAA ATPase family. (389 aa)
	ANOM_005459	Abhydrolase_3 domain-containing protein. (318 aa)
	ANOM_006256	Lipase/esterase. (488 aa)
	ANOM_006013	Uncharacterized protein. (834 aa)
	ANOM_003651	Putative histone-lysine N-methyltransferase (Ash1). (815 aa)
	ANOM_005331	Transcriptional repressor rco-1. (589 aa)
	ANOM_008859	Putative YT521-B-like splicing factor. (623 aa)
	ANOM_007286	RPEL repeat protein. (177 aa)
	ANOM_008854	Serine/threonine-protein kinase KIN28; Belongs to the protein kinase superfamily. (403 aa)
	ANOM_008067	Zn(II)2Cys6 transcription factor. (793 aa)
	ANOM_008792	SAGA complex component (Sgf29). (438 aa)
	ANOM_007996	C6 zinc finger domain protein. (702 aa)
	ANOM_007981	Putative nucleosome remodeling complex ATPase subunit (Snf2h). (962 aa)
	ANOM_009813	APSES transcription factor (MbpA). (896 aa)
	ANOM_009402	S1 motif domain-containing protein. (2235 aa)
	ANOM_009259	Uncharacterized protein. (994 aa)
	ANOM_009512	C6 zinc finger domain protein. (754 aa)
	ANOM_009524	MADS box transcription factor Mcm1. (313 aa)
	ANOM_009852	Putative C2H2 transcription factor. (569 aa)
	ANOM_009655	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1079 aa)
	ANOM_009032	Helix-loop-helix DNA-binding domain protein. (140 aa)
	ANOM_008405	Putative HLH transcription factor (PalcA). (686 aa)
	ANOM_009387	Uncharacterized protein. (194 aa)
	ANOM_006746	Putative CDK9. (538 aa)
	ANOM_008286	M protein repeat protein. (860 aa)
	ANOM_008281	Prefoldin subunit 5. (172 aa)
	ANOM_006802	CCAAT-binding factor complex subunit HapE. (278 aa)
	ANOM_009129	Uncharacterized protein. (686 aa)
	ANOM_010733	HTH CENPB-type domain-containing protein. (280 aa)
	KAE1	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (339 aa)
	ANOM_009630	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (112 aa)
	ANOM_010043	Histone deacetylase HosB. (1084 aa)
	ANOM_010218	Transcriptional corepressor Cyc8. (876 aa)
	ANOM_010706	Putative HMG box protein. (493 aa)
	ANOM_009564	Putative lipase/esterase. (363 aa)
	ANOM_009896	CBF/NF-Y family transcription factor. (175 aa)
	ANOM_010874	Uncharacterized protein. (396 aa)
	ANOM_011774	UDP-N-acetylglucosaminyltransferase. (1641 aa)
	ANOM_009678	Uncharacterized protein. (631 aa)
	ANOM_011775	MYB family conidiophore development protein FlbD. (323 aa)
	ANOM_010578	Beta-lactamase family protein. (347 aa)
	ANOM_011486	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (714 aa)
	ANOM_011162	Transcriptional regulator PacG/VIB-1. (591 aa)
	ANOM_011480	HLH transcription factor (Hpa3). (483 aa)
	ANOM_011118	GATA factor SREP. (551 aa)
	ANOM_011255	Putative C6 transcription factor (UaY). (1052 aa)
	ANOM_011547	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (556 aa)
	ANOM_010352	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (167 aa)
	ANOM_011065	HLH transcription factor (GlcD gamma). (520 aa)
	ANOM_011692	Uncharacterized protein. (357 aa)
	ANOM_011396	Jumonji family transcription factor. (776 aa)
	ANOM_011721	Pol II transcription elongation factor subunit Cdc73. (470 aa)

Your Current Organism:

Aspergillus nomius

NCBI taxonomy Id: 1509407
Other names: A. nomius NRRL 13137, Aspergillus nomius NRRL 13137, Aspergillus nomius NRRL13137

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANOM_000135	ANOM_000175	A0A0L1JIH8	A0A0L1JIU2	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.447
ANOM_000135	ANOM_000633	A0A0L1JIH8	A0A0L1JGT4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	DNA helicase ino80.	0.430
ANOM_000135	ANOM_000640	A0A0L1JIH8	A0A0L1JGT9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Chromatin structure-remodeling complex subunit snf2.	0.477
ANOM_000135	ANOM_001166	A0A0L1JIH8	A0A0L1JDZ2	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	SRF-type transcription factor RlmA.	0.734
ANOM_000135	ANOM_003651	A0A0L1JIH8	A0A0L1J2A2	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative histone-lysine N-methyltransferase (Ash1).	0.476
ANOM_000135	ANOM_004707	A0A0L1JIH8	A0A0L1J3L1	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative GATA transcription factor (AreB).	0.914
ANOM_000135	ANOM_005331	A0A0L1JIH8	A0A0L1J1Y9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Transcriptional repressor rco-1.	0.413
ANOM_000135	ANOM_005548	A0A0L1JIH8	A0A0L1IZZ8	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	BZIP transcription factor HacA.	0.464
ANOM_000135	ANOM_006184	A0A0L1JIH8	A0A0L1J002	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Forkhead box protein L2.	0.401
ANOM_000135	ANOM_006621	A0A0L1JIH8	A0A0L1IZW4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	ISWI chromatin-remodeling complex ATPase ISW2.	0.462
ANOM_000135	ANOM_006719	A0A0L1JIH8	A0A0L1J1U5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Forkhead transcription factor Fkh1/2.	0.401
ANOM_000135	ANOM_006949	A0A0L1JIH8	A0A0L1IY14	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	RNA polymerase-associated protein LEO1.	0.662
ANOM_000135	ANOM_007981	A0A0L1JIH8	A0A0L1IUA2	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Putative nucleosome remodeling complex ATPase subunit (Snf2h).	0.462
ANOM_000135	ANOM_008595	A0A0L1JIH8	A0A0L1IXE7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	WD_REPEATS_REGION domain-containing protein.	0.413
ANOM_000135	ANOM_009259	A0A0L1JIH8	A0A0L1ITI4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.413
ANOM_000135	ANOM_009402	A0A0L1JIH8	A0A0L1ITU9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	S1 motif domain-containing protein.	0.404
ANOM_000135	ANOM_009524	A0A0L1JIH8	A0A0L1ITA0	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	MADS box transcription factor Mcm1.	0.427
ANOM_000135	ANOM_009655	A0A0L1JIH8	A0A0L1ISF9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.728
ANOM_000135	ANOM_010218	A0A0L1JIH8	A0A0L1IQ65	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Transcriptional corepressor Cyc8.	0.415
ANOM_000135	ANOM_011118	A0A0L1JIH8	A0A0L1IMF3	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	GATA factor SREP.	0.411