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argG argG tmcAL tmcAL CBH21871.1 CBH21871.1 CBH21806.1 CBH21806.1 thiI thiI nadD nadD guaA guaA CBH20402.1 CBH20402.1 tyrS tyrS trmU trmU phr phr argS argS etfA etfA etfB etfB glnS glnS CBH21138.1 CBH21138.1 CBH21131.1 CBH21131.1 tilS tilS valS valS metS metS CBH20493.1 CBH20493.1 asnB asnB CBH21346.1 CBH21346.1 CBH22600.1 CBH22600.1 CBH22547.1 CBH22547.1 gltX gltX cysS cysS leuS leuS CBH22064.1 CBH22064.1 ileS ileS nadE nadE trpS trpS coaD coaD
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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argGArgininosuccinate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (421 aa)
tmcALConserved protein of unknown function; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of elongator tRNA(Met), using acetate and ATP as substrates. First activates an acetate ion to form acetyladenylate (Ac- AMP) and then transfers the acetyl group to tRNA to form ac(4)C34. (410 aa)
CBH21871.1ATP-utilizing enzyme of the PP-loop superfamily (modular protein). (428 aa)
CBH21806.1Bifunctional riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (310 aa)
thiIPutative thiamine biosynthesis protein thiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (394 aa)
nadDNicotinic acid mononucleotide adenylyltransferase, NAD(P)-dependent; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (200 aa)
guaAGMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. (509 aa)
CBH20402.1Putative universal stress protein family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (143 aa)
tyrSTyrosyl-tRNA synthetase 1 (Tyrosine--tRNA ligase 1) (TyrRS 1); Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (408 aa)
trmUtRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (372 aa)
phrDeoxyribodipyrimidine photo-lyase (DNA photolyase) (Photoreactivating enzyme). (447 aa)
argSArginyl-tRNA synthetase 2 (Arginine--tRNA ligase 2) (ArgRS 2). (566 aa)
etfAElectron transfer flavoprotein (alpha subunit). (336 aa)
etfBElectron transfer flavoprotein (beta subunit). (260 aa)
glnSglutamyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (559 aa)
CBH21138.1PP-loop family protein; Belongs to the TtcA family. (290 aa)
CBH21131.1Protein of unknown function; No homology to any previously reported sequences. (141 aa)
tilStRNAile lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (464 aa)
valSvalyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (884 aa)
metSmethionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (651 aa)
CBH20493.1Homologs of previously reported genes of unknown function. (377 aa)
asnBAsparagine synthase (Glutamine-hydrolyzing). (605 aa)
CBH21346.1UspA. (131 aa)
CBH22600.1Putative NH3-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (247 aa)
CBH22547.1Homologs of previously reported genes of unknown function. (218 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (495 aa)
cysScysteinyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa)
leuSleucyl-tRNA synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (800 aa)
CBH22064.1Cytidyltransferase-related domain. (1594 aa)
ileSIsoleucyl-tRNA synthetase 2 (Isoleucine--tRNA ligase 2) (IleRS 2); Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 [...] (1034 aa)
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (249 aa)
trpStryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (339 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (162 aa)
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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