STRINGSTRING
asd asd pycA pycA CBH20207.1 CBH20207.1 mtbC mtbC CBH20210.1 CBH20210.1 astC astC CBH20326.1 CBH20326.1 CBH20381.1 CBH20381.1 CBH20510.1 CBH20510.1 fucA fucA glyA glyA lysA lysA fsaB fsaB prsA prsA CBH20616.1 CBH20616.1 vorB vorB CBH20618.1 CBH20618.1 CBH20619.1 CBH20619.1 folD folD ydgJ ydgJ glcK glcK ltaE ltaE pgi pgi gapA gapA pgk pgk tpiA tpiA gpmI gpmI eno eno CBH20799.1 CBH20799.1 CBH20809.1 CBH20809.1 CBH20810.1 CBH20810.1 porC porC CBH20880.1 CBH20880.1 CBH20918.1 CBH20918.1 CBH20953.1 CBH20953.1 CBH21001.1 CBH21001.1 accB accB accC accC accD accD accA accA CBH21026.1 CBH21026.1 pfp pfp arcC arcC CBH21063.1 CBH21063.1 CBH21064.1 CBH21064.1 yqjC yqjC CBH21068.1 CBH21068.1 gcdC gcdC oadB oadB hemA hemA CBH21120.1 CBH21120.1 hemC hemC CBH21122.1 CBH21122.1 hemB hemB hemL hemL CBH21189.1 CBH21189.1 CBH21190.1 CBH21190.1 atoD atoD atoA atoA CBH21253.1 CBH21253.1 atoB atoB CBH21255.1 CBH21255.1 CBH21276.1 CBH21276.1 vorB-2 vorB-2 CBH21278.1 CBH21278.1 CBH21279.1 CBH21279.1 CBH21280.1 CBH21280.1 fhs fhs CBH21285.1 CBH21285.1 acoL acoL CBH21288.1 CBH21288.1 CBH21289.1 CBH21289.1 CBH21290.1 CBH21290.1 CBH21291.1 CBH21291.1 gatY gatY CBH21354.1 CBH21354.1 icd icd CBH21364.1 CBH21364.1 glyA-2 glyA-2 ackA ackA mgsA mgsA CBH21533.1 CBH21533.1 CBH21579.1 CBH21579.1 korC korC korB korB korA korA CBH21594.1 CBH21594.1 pykF pykF pfkA pfkA CBH21785.1 CBH21785.1 CBH21808.1 CBH21808.1 tktB tktB ppdK ppdK CBH21933.1 CBH21933.1 dapH dapH dapB dapB dapA dapA rpe rpe dapF dapF CBH22033.1 CBH22033.1 CBH22035.1 CBH22035.1 asrC asrC asrB asrB asrA asrA CBH22153.1 CBH22153.1 rpiB rpiB glpX glpX glpX-2 glpX-2 CBH22360.1 CBH22360.1 cysK cysK CBH22389.1 CBH22389.1 ybhJ ybhJ gdhA gdhA CBH22411.1 CBH22411.1 pflB pflB thrC thrC thrB thrB CBH22598.1 CBH22598.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (327 aa)
pycAPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1144 aa)
CBH20207.1Homologs of previously reported genes of unknown function; Belongs to the uroporphyrinogen decarboxylase family. (288 aa)
mtbCDimethylamine corrinoid protein 2. (218 aa)
CBH20210.1Homologs of previously reported genes of unknown function; Belongs to the uroporphyrinogen decarboxylase family. (343 aa)
astCSuccinylornithine transaminase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa)
CBH20326.13-hydroxyacyl-CoA dehydrogenase precursor. (319 aa)
CBH20381.1Acetaldehyde dehydrogenase / alcohol dehydrogenase-like protein. (494 aa)
CBH20510.1Putative FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (438 aa)
fucAL-fuculose phosphate aldolase. (212 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa)
fsaBFructose-6-phosphate aldolase 2; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
prsAPhosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa)
CBH20616.14Fe-4S ferredoxin, iron-sulfur binding domain protein. (72 aa)
vorBKetoisovalerate oxidoreductase subunit vorB (VOR) (2-oxoisovalerate oxidoreductase beta chain) (2-oxoisovalerate ferredoxin reductase subunit beta). (351 aa)
CBH20618.1Putative subunit of oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (249 aa)
CBH20619.1Putative subunit of oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (184 aa)
folDBifunctional protein folD [Includes: Methylenetetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (294 aa)
ydgJPutative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (356 aa)
glcKGlucokinase. (318 aa)
ltaEL-allo-threonine aldolase, PLP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (342 aa)
pgiGlucose-6-phosphate isomerase (GPI) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI); Belongs to the GPI family. (453 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase A; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (339 aa)
pgkPhosphoglycerate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the phosphoglycerate kinase family. (398 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
gpmIPhosphoglycero mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (507 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
CBH20799.1Class II aldolase/adducin-like. (282 aa)
CBH20809.1Putative Coenzyme A transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (278 aa)
CBH20810.1Putative glutaconate CoA-transferase, subunit B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (249 aa)
porCPyruvate synthase subunit porC (Pyruvate oxidoreductase gamma chain) (POR) (Pyruvic-ferredoxin oxidoreductase subunit gamma). (178 aa)
CBH20880.1Pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit (modular protein). (86 aa)
CBH20918.1Putative GCN5-related N-acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (424 aa)
CBH20953.1Aldehyde:ferredoxin oxidoreductase. (579 aa)
CBH21001.1Homologs of previously reported genes of unknown function. (562 aa)
accBAcetyl CoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (142 aa)
accCacetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa)
accDacetyl-CoA carboxylase, beta (carboxyltranferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (264 aa)
accAAcetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (265 aa)
CBH21026.1Homoserine dehydrogenase. (403 aa)
pfpPhosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (406 aa)
arcCCarbamate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family. (311 aa)
CBH21063.1Methylmalonyl-CoA mutase, large subunit. (559 aa)
CBH21064.1Cobalamin B12-binding domain protein. (134 aa)
yqjCPutative lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (135 aa)
CBH21068.1Sodium pump decarboxylase, gamma subunit; Catalyzes the decarboxylation of oxaloacetate coupled to Na(+) translocation; Belongs to the OadG family. (134 aa)
gcdCGlutaconyl-CoA decarboxylase subunit gamma (Biotin carrier). (129 aa)
oadBOxaloacetate decarboxylase beta chain; Tunnel subunit of the primary sodium pump glutaconyl-CoA decarboxylase (GCD). (403 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (415 aa)
CBH21120.1Homologs of previously reported genes of unknown function. (202 aa)
hemCPorphobilinogen deaminase (hydroxymethylbilane synthase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (304 aa)
CBH21122.1Uroporphyrinogen III synthase/methyltransferase. (498 aa)
hemBPorphobilinogen synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (319 aa)
hemLGlutamate-1-semialdehyde aminotransferase (aminomutase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (431 aa)
CBH21189.1Putative fumarate hydratase subunit beta (Fumarase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (184 aa)
CBH21190.1Putative fumarate hydratase subunit alpha (Fumarase); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (280 aa)
atoDacetyl-CoA:acetoacetyl-CoA transferase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier. (216 aa)
atoAacetyl-CoA:acetoacetyl-CoA transferase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; carrier. (215 aa)
CBH21253.13-hydroxybutyryl-CoA dehydrogenase. (279 aa)
atoBacetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; carrier; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
CBH21255.1Acyl-CoA dehydrogenase, short-chain specific. (379 aa)
CBH21276.14Fe-4S ferredoxin, iron-sulfur binding domain protein. (79 aa)
vorB-2Ketoisovalerate oxidoreductase subunit vorB (VOR) (2-oxoisovalerate oxidoreductase beta chain) (2-oxoisovalerate ferredoxin reductase subunit beta). (356 aa)
CBH21278.1Thiamine pyrophosphate protein domain protein TPP-binding. (251 aa)
CBH21279.1Pyruvate ferredoxin/flavodoxin oxidoreductase. (176 aa)
CBH21280.1Carbon monoxide dehydrogenase 1 (CODH 1); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (629 aa)
fhsFormate-tetrahydrofolate ligase (Formyltetrahydrofolate synthetase) (FHS) (FTHFS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the formate--tetrahydrofolate ligase family. (558 aa)
CBH21285.1Methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (302 aa)
acoLDihydrolipoamide dehydrogenase. (457 aa)
CBH21288.1Corrinoid/iron-sulfur protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (314 aa)
CBH21289.1Corrinoid-iron-sulfur protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (451 aa)
CBH21290.15-methyltetrahydrofolate corrinoid/iron sulfur protein methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (261 aa)
CBH21291.1Acetyl-CoA synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (708 aa)
gatYD-tagatose 1,6-bisphosphate aldolase 2, catalytic subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (311 aa)
CBH21354.1Glutamine synthetase, catalytic region. (638 aa)
icdIsocitrate dehydrogenase, specific for NADP+; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. (334 aa)
CBH21364.1Methylcitrate synthase. (446 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (413 aa)
ackAAcetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (399 aa)
mgsAMethylglyoxal synthase (MGS); Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (147 aa)
CBH21533.1Aspartokinase; Belongs to the aspartokinase family. (442 aa)
CBH21579.1Rhodanese-like domain protein. (275 aa)
korC2-oxoglutarate synthase subunit korC (2-ketoglutarate oxidoreductase gamma chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit gamma). (176 aa)
korB2-oxoglutarate synthase subunit korB (2-ketoglutarate oxidoreductase beta chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit beta). (266 aa)
korA2-oxoglutarate synthase subunit korA (2-ketoglutarate oxidoreductase alpha chain) (KOR) (2-oxoglutarate-ferredoxin oxidoreductase subunit alpha). (382 aa)
CBH21594.1Ferredoxin. (62 aa)
pykFPyruvate kinase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family. (583 aa)
pfkA6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa)
CBH21785.1Phosphoglucomutase. (576 aa)
CBH21808.1Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (326 aa)
tktBTransketolase 2, thiamin-binding; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (661 aa)
ppdKPyruvate, phosphate dikinase (Pyruvate, orthophosphate dikinase); Belongs to the PEP-utilizing enzyme family. (881 aa)
CBH21933.1Predicted phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (303 aa)
dapHTetrahydrodipicolinate N-acetyltransferase; Catalyzes the transfer of an acetyl group from acetyl-CoA to tetrahydrodipicolinate. (238 aa)
dapBDihydrodipicolinate reductase (DHPR); Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (253 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (297 aa)
rpeD-ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family. (218 aa)
dapFDiaminopimelate epimerase (DAP epimerase); Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (281 aa)
CBH22033.1Homologs of previously reported genes of unknown function. (1178 aa)
CBH22035.1Putative propanediol utilization protein; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (190 aa)
asrCAnaerobic sulfite reductase subunit C; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (333 aa)
asrBAnaerobic sulfite reductase subunit B. (262 aa)
asrAAnaerobic sulfite reductase subunit A (Anaerobic sulfite reductase iron-sulfur subunit). (339 aa)
CBH22153.12-haloalkanoic acid dehalogenase. (227 aa)
rpiBRibose 5-phosphate isomerase B/allose 6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (151 aa)
glpXFructose 1,6-bisphosphatase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (323 aa)
glpX-2Fructose 1,6-bisphosphatase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (331 aa)
CBH22360.1Serine acetyltransferase (SAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (191 aa)
cysKCysteine synthase A, O-acetylserine sulfhydrolase A subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (304 aa)
CBH22389.1Homologs of previously reported genes of unknown function. (173 aa)
ybhJPutative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (773 aa)
gdhAGlutamate dehydrogenase, NADP-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
CBH22411.1Molybdopterin oxidoreductase. (1195 aa)
pflBPyruvate formate lyase I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (747 aa)
thrCThrC; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (353 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (298 aa)
CBH22598.1Putative Ribose-phosphate pyrophosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (269 aa)
Your Current Organism:
Acetoanaerobium sticklandii
NCBI taxonomy Id: 1511
Other names: A. sticklandii, ATCC 12662, BCRC 14485, CCRC 14485, CCRC:14485, CCUG 9281, Clostridium sticklandii, DSM 519, NCIMB 10654, strain StadtmanHF
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