STRINGSTRING
murB murB leuB leuB ilvC_2 ilvC_2 AJG96938.1 AJG96938.1 mtlD mtlD AJG96997.1 AJG96997.1 mmgB mmgB guaB_2 guaB_2 AJG97161.1 AJG97161.1 AJG97241.2 AJG97241.2 AJG97272.1 AJG97272.1 AJG97575.1 AJG97575.1 ldh-3 ldh-3 fabG_9 fabG_9 AJG97759.1 AJG97759.1 AJG97764.1 AJG97764.1 AJG97788.2 AJG97788.2 AJG97802.1 AJG97802.1 gpsA gpsA dxr dxr ribD ribD panE panE hisD hisD gutB gutB AJG98222.1 AJG98222.1 AJG98287.1 AJG98287.1 AJG98321.1 AJG98321.1 AJG98368.1 AJG98368.1 adhE_2 adhE_2 AJG98569.2 AJG98569.2 uxaB_1 uxaB_1 uxaB uxaB AJG98691.1 AJG98691.1 AJG98696.1 AJG98696.1 AJG98705.1 AJG98705.1 AJG98714.1 AJG98714.1 AJG99011.1 AJG99011.1 adhA adhA gntZ gntZ AJG99064.1 AJG99064.1 AJG99065.1 AJG99065.1 AJG99193.1 AJG99193.1 gldA gldA licH_1 licH_1 AJG99502.1 AJG99502.1 AJG99593.1 AJG99593.1 AJG99595.2 AJG99595.2 AJG99676.1 AJG99676.1 AJG99733.1 AJG99733.1 AJG99877.1 AJG99877.1 AJH00164.1 AJH00164.1 AJH00475.1 AJH00475.1 AJH00501.1 AJH00501.1 AJH00546.1 AJH00546.1 AJH00597.1 AJH00597.1 AJH00699.1 AJH00699.1 AJH00844.2 AJH00844.2 AJH00922.1 AJH00922.1 AJH01048.1 AJH01048.1 AJH01077.1 AJH01077.1 AJH01095.2 AJH01095.2 ldh ldh AJH01135.1 AJH01135.1 AJH01239.1 AJH01239.1 AJH01407.1 AJH01407.1 AJH01412.1 AJH01412.1 AJH01608.1 AJH01608.1 aroE aroE aroE-2 aroE-2 aroE-3 aroE-3 AJH01652.1 AJH01652.1 AJH01665.1 AJH01665.1 licH_3 licH_3 AJH01767.1 AJH01767.1 AJH01771.1 AJH01771.1 AJH01773.1 AJH01773.1 AJH01802.1 AJH01802.1 AJH01813.2 AJH01813.2 AJH01875.1 AJH01875.1 ldh-2 ldh-2 AJH02257.1 AJH02257.1 AJH02143.1 AJH02143.1 AJH02064.1 AJH02064.1 wbpA_2 wbpA_2 AJH01932.1 AJH01932.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (304 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa)
ilvC_2Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (334 aa)
AJG96938.1Sorbitol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
mtlDMannitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AJG96997.1Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (860 aa)
mmgB3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
guaB_2IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (485 aa)
AJG97161.1Lactaldehyde reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
AJG97241.2Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
AJG97272.1Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AJG97575.1Hydroxyacid dehydrogenase; Involved in the metabolism of aromatic amino acids; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
ldh-3L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
fabG_9beta-ketoacyl-ACP reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
AJG97759.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
AJG97764.1NAD(P)-dependent oxidoreductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (302 aa)
AJG97788.2Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)
AJG97802.1NAD(P)-dependent oxidoreductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (293 aa)
gpsAGlycerol-3-phosphate dehydrogenase; Catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (330 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (387 aa)
ribDDiaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (361 aa)
panE2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (310 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa)
gutBButanediol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AJG98222.1Theronine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
AJG98287.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (84 aa)
AJG98321.1Lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (327 aa)
AJG98368.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)
adhE_2Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
AJG98569.2Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
uxaB_1Altronate oxidoreductase; Catalyzes the formation of D-tagaturonate from D-altronate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. UxaB subfamily. (482 aa)
uxaBAltronate oxidoreductase; Catalyzes the formation of D-tagaturonate from D-altronate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannitol dehydrogenase family. UxaB subfamily. (482 aa)
AJG98691.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
AJG98696.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
AJG98705.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)
AJG98714.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (307 aa)
AJG99011.1Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
adhAButanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
gntZ6-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
AJG99064.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (333 aa)
AJG99065.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
AJG99193.1Ketopantoate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
gldAGlycerol dehydrogenase; Forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa)
licH_16-phospho-beta-glucosidase; Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
AJG99502.1NAD(P)-dependent oxidoreductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (293 aa)
AJG99593.1Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (348 aa)
AJG99595.2Glycerol-1-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
AJG99676.1Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AJG99733.1Glycerol-1-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AJG99877.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
AJH00164.1L-threonine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AJH00475.1Zn-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
AJH00501.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)
AJH00546.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (319 aa)
AJH00597.1Ketopantoate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
AJH00699.1Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AJH00844.23-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
AJH00922.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (93 aa)
AJH01048.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AJH01077.16-phospho-beta-glucosidase; Catalyzes the fromation of N-acetyl-D-glucosamine and N-acetyl-D-glucosamine-6-phosphate from diacetylchitobiose-6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
AJH01095.2Propanediol utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
AJH01135.1Glycerol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (353 aa)
AJH01239.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
AJH01407.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
AJH01412.1Alpha-glucosidase/alpha-galactosidase; Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
AJH01608.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
aroEQuinate/shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
aroE-2Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (289 aa)
aroE-3Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (269 aa)
AJH01652.1L-arabinose utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
AJH01665.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa)
licH_36-phospho-beta-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
AJH01767.16-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
AJH01771.1UDP-N-acetyl-D-glucosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)
AJH01773.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (345 aa)
AJH01802.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
AJH01813.2Galactitol-1-phosphate 5-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
AJH01875.16-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
ldh-2L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (315 aa)
AJH02257.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
AJH02143.16-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
AJH02064.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (302 aa)
wbpA_2UDP-N-acetyl-D-glucosamine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (438 aa)
AJH01932.1Alpha-glucosidase/alpha-galactosidase; Catalyses the hydrolysis of terminal non-reducing alpha-D-galactose residues in alpha-D-galactosides; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
Your Current Organism:
Clostridium beijerinckii
NCBI taxonomy Id: 1520
Other names: ATCC 25752, BCRC 14488, C. beijerinckii, CCUG 56442, CIP 104308, Clostridium rubrum, Clostridium sp. H18, DSM 791, LMG 5716, LMG:5716, NCIMB 9362, NCTC 13035
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