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| | rplR | 50S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (119 aa) |
| | rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (180 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rplX | 50S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rpsQ | 30S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rpmC | 50S ribosomal protein L29; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL29 family. (70 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (144 aa) |
| | rpsC | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (221 aa) |
| | rplV | 50S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (111 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (90 aa) |
| | rplB | 50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (277 aa) |
| | rplW | 50S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (98 aa) |
| | rplD | 50S ribosomal protein L4; Forms part of the polypeptide exit tunnel. (206 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (209 aa) |
| | rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (102 aa) |
| | tuf-2 | Elongation factor Tu; EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; Derived by automated computational analysis using gene prediction method: Protein Homology. (397 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (688 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | rpsL | 30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (125 aa) |
| | rplL | 50S ribosomal protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa) |
| | rplJ | 50S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (167 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (229 aa) |
| | rplK | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (141 aa) |
| | rpmG | 50S ribosomal protein L33; In Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; Derived by automated computational analysis using gene prediction method: Protein Homology. (49 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (397 aa) |
| | cysS | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (466 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...] (570 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (458 aa) |
| | glyQS | glycine--tRNA ligase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (463 aa) |
| | lysS | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (501 aa) |
| | yugI | RNA-binding protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa) |
| | pth | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (191 aa) |
| | glmU | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa) |
| | murC_1 | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (459 aa) |
| | asnS | asparagine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa) |
| | lgt_1 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (256 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (645 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1037 aa) |
| | yrpC_1 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (259 aa) |
| | AJG96710.1 | L,D-transpeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (393 aa) |
| | rpsN1 | 30S ribosomal protein S14 type Z; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site. (61 aa) |
| | gatB | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (479 aa) |
| | gatA | aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (479 aa) |
| | gatC_3 | glutamyl-tRNA amidotransferase; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (94 aa) |
| | asnS_2 | aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily. (429 aa) |
| | fmt-2 | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (317 aa) |
| | AJH00225.2 | methionine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (698 aa) |
| | thrS-2 | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (635 aa) |
| | def1 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (150 aa) |
| | AJH00504.2 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (136 aa) |
| | lysS-2 | lysine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. (508 aa) |
| | murI | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (267 aa) |
| | AJH00802.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa) |
| | AJH01069.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa) |
| | AJH01147.1 | Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa) |
| | AJH01149.1 | Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa) |
| | AJH01249.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (481 aa) |
| | AJH01279.1 | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (828 aa) |
| | AJH01325.2 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa) |
| | AJH01333.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (355 aa) |
| | AJH01336.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (378 aa) |
| | AJH01340.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (605 aa) |
| | murG | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (359 aa) |
| | dltC_1 | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. (75 aa) |
| | AJH01383.1 | D-alanyl-lipoteichoic acid biosynthesis protein DltB; Could be involved in the transport of activated D-alanine through the membrane. (384 aa) |
| | dltA_2 | D-alanine--poly(phosphoribitol) ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-de [...] (504 aa) |
| | AJH01386.1 | D-alanyl-lipoteichoic acid biosynthesis protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. (394 aa) |
| | AJH01451.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (170 aa) |
| | leuS | leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (816 aa) |
| | tyrS_2 | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (406 aa) |
| | wlbE | Glycosyltransferase WbuB; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa) |
| | gtf1_2 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa) |
| | wbpI | UDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (354 aa) |
| | AJH01696.1 | O-antigen polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa) |
| | AJH01699.1 | Lipopolysaccharide cholinephosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa) |
| | AJH01729.1 | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa) |
| | rfbX_3 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa) |
| | prfC | Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (531 aa) |
| | AJH01793.1 | Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (476 aa) |
| | AJH01796.1 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa) |
| | AJH01797.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa) |
| | AJG99477.1 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (304 aa) |
| | AJG99490.2 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa) |
| | AJG99496.1 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa) |
| | AJG99521.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa) |
| | AJG99536.1 | aminoacyl-tRNA deacylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily. (162 aa) |
| | tyrS_1 | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (403 aa) |
| | AJG99762.1 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa) |
| | lgt-2 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (277 aa) |
| | lgt_3 | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (260 aa) |
| | AJH01799.1 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa) |
| | AJH01800.1 | Glycosyl transferase family 28; Derived by automated computational analysis using gene prediction method: Protein Homology. (162 aa) |
| | AJH01801.1 | UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa) |
| | AJH01804.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (100 aa) |
| | AJH01805.2 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | AJH01806.2 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (229 aa) |
| | AJH01825.1 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa) |
| | AJH01826.1 | Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa) |
| | AJH01869.1 | Phosphosugar isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (304 aa) |
| | fusA-2 | Elongation factor G; EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; Derived by automated computational analysis using gene prediction method: Protein Homology. (693 aa) |
| | murAB | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (421 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (148 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (86 aa) |
| | rpsF | 30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. (95 aa) |
| | rpmH | 50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL34 family. (44 aa) |
| | AMK50448.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa) |
| | AMK50518.1 | Glucose-1-phosphate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (386 aa) |
| | glgA | Glycogen synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (479 aa) |
| | AMK50536.1 | Glycogen-branching enzyme; Catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa) |
| | rpsU_2 | 30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family. (58 aa) |
| | AJG99287.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (357 aa) |
| | AJG98975.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa) |
| | dacB_1 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (284 aa) |
| | dacF | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (396 aa) |
| | valS | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (881 aa) |
| | AJG98467.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa) |
| | AJG98466.1 | Dolichyl-phosphate-mannose--protein mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (739 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (185 aa) |
| | AJG98416.1 | Ferrous iron transporter A; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa) |
| | spoVE | Rod shape-determining protein RodA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SEDS family. (378 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (326 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (450 aa) |
| | murE-2 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (486 aa) |
| | pheT | phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (792 aa) |
| | pheS | phenylalanine--tRNA ligase subunit alpha; Catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (339 aa) |
| | rplT | 50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (119 aa) |
| | rpmI | 50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | infC | Translation initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (173 aa) |
| | rpsD | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (198 aa) |
| | aspS | aspartate--tRNA ligase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (599 aa) |
| | hisS_1 | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (417 aa) |
| | serS | serine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa) |
| | glnS | glutamine--tRNA ligase; Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (553 aa) |
| | lgt | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (258 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (489 aa) |
| | AJG98043.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa) |
| | rpsO | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (87 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (695 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | tsf | Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (305 aa) |
| | rpsB | 30S ribosomal protein S2; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS2 family. (233 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (116 aa) |
| | AJG97916.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0109 family. (75 aa) |
| | rpsP | 30S ribosomal protein S16; Binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS16 family. (81 aa) |
| | rpmF | 50S ribosomal protein L32; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL32 family. (60 aa) |
| | rpmB | 50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL28 family. (63 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (308 aa) |
| | def_1 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (152 aa) |
| | sigG | RNA polymerase sigma-G factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (257 aa) |
| | sigE | RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (232 aa) |
| | AJG97851.2 | Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa) |
| | mltG | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (341 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (879 aa) |
| | AJG97838.2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa) |
| | AJG97822.1 | Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the membrane-bound acyltransferase family. (532 aa) |
| | AJG97800.1 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (304 aa) |
| | AJG97797.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (488 aa) |
| | AJG97796.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (362 aa) |
| | AJG97789.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa) |
| | AJG97787.1 | UDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (373 aa) |
| | AJG97785.2 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa) |
| | AJG97784.1 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa) |
| | AJG97783.1 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | AJG97772.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (509 aa) |
| | AJG97762.1 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (312 aa) |
| | AJG97761.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (288 aa) |
| | AJG97760.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa) |
| | AJG97756.1 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa) |
| | AJG97755.2 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa) |
| | argS | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (563 aa) |
| | uppP | Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (286 aa) |
| | AJG97660.1 | Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa) |
| | AJG97659.1 | Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa) |
| | AJG97658.1 | Glycosyl transferase group 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (429 aa) |
| | murJ | Murein biosynthesis protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (508 aa) |
| | ctc | 50S ribosomal protein L25/general stress protein Ctc; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (189 aa) |
| | AJG97639.1 | Capsular biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa) |
| | AJG97621.1 | UDP-N-acetylmuramyl peptide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa) |
| | cobQ_1 | Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa) |
| | AJG97619.1 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (440 aa) |
| | rpsU_1 | 30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bS21 family. (58 aa) |
| | lepA | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (601 aa) |
| | rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (87 aa) |
| | trpS | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (339 aa) |
| | AJG97457.1 | Peptidoglycan-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa) |
| | AJG97456.2 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa) |
| | greA | Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides. (154 aa) |
| | smpB | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (156 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (301 aa) |
| | AJG97226.1 | D-alanyl-D-alanine carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (411 aa) |
| | rpmA | 50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL27 family. (99 aa) |
| | rplU | 50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | prfB | Peptide chain release factor 2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (324 aa) |
| | murA | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa) |
| | AJG97112.2 | UDP-N-acetyl glucosamine 2-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (396 aa) |
| | prfA | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa) |
| | rpmE | 50S ribosomal protein L31; Binds the 23S rRNA. (69 aa) |
| | AJG97088.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa) |
| | AJG97084.1 | Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa) |
| | AJG97073.1 | Sulfatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (627 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (643 aa) |
| | rpsI | 30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rplM | 50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (144 aa) |
| | rplQ | 50S ribosomal protein L17; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa) |
| | rpsD_1 | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (131 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (122 aa) |
| | rpmJ | 50S ribosomal protein L36; Smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; Derived by automated computational analysis using gene prediction method: Protein Homology. (37 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | AJG96888.1 | LSU ribosomal protein L14E; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa) |
| | rplO | 50S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (146 aa) |
| | rpmD | 50S ribosomal protein L30; Derived by automated computational analysis using gene prediction method: Protein Homology. (59 aa) |
| | rpsE | 30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (165 aa) |
