(5 nodes) (2010) Assessment of heterologous butyrate and butanol pathway activity by measurement of intracellular pathway intermediates in recombinant Escherichia coli. network (Clostridium beijerinckii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	buk-2	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family. (356 aa)
	buk	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family. (355 aa)
	mmgB	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	atoB	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
	buk2_3	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family. (356 aa)

Your Current Organism:

Clostridium beijerinckii

NCBI taxonomy Id: 1520
Other names: ATCC 25752, BCRC 14488, C. beijerinckii, CCUG 56442, CIP 104308, Clostridium rubrum, Clostridium sp. H18, DSM 791, LMG 5716, LMG:5716, NCIMB 9362, NCTC 13035

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
atoB	buk	LF65_04088	LF65_00242	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.657
atoB	buk-2	LF65_04088	LF65_04509	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.657
atoB	buk2_3	LF65_04088	LF65_05155	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.657
atoB	mmgB	LF65_04088	LF65_00359	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
buk	atoB	LF65_00242	LF65_04088	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.657
buk	buk-2	LF65_00242	LF65_04509	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.901
buk	buk2_3	LF65_00242	LF65_05155	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.902
buk	mmgB	LF65_00242	LF65_00359	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
buk-2	atoB	LF65_04509	LF65_04088	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.657
buk-2	buk	LF65_04509	LF65_00242	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.901
buk-2	buk2_3	LF65_04509	LF65_05155	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.900
buk-2	mmgB	LF65_04509	LF65_00359	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
buk2_3	atoB	LF65_05155	LF65_04088	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.657
buk2_3	buk	LF65_05155	LF65_00242	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.902
buk2_3	buk-2	LF65_05155	LF65_04509	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.900
buk2_3	mmgB	LF65_05155	LF65_00359	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.778
mmgB	atoB	LF65_00359	LF65_04088	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family.	0.999
mmgB	buk	LF65_00359	LF65_00242	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.778
mmgB	buk-2	LF65_00359	LF65_04509	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.778
mmgB	buk2_3	LF65_00359	LF65_05155	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Butyrate kinase; Catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family.	0.778

Server load: low (28%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About