(6 nodes) (2015) Butanol production in S. cerevisiae via a synthetic ABE pathway is enhanced by specific metabolic engineering and butanol resistance. network (Clostridium beijerinckii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	prs_2	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
	AJG97025.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	mmgB	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	adhE_2	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
	acdA_1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)
	AJH01598.1	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (379 aa)

Your Current Organism:

Clostridium beijerinckii

NCBI taxonomy Id: 1520
Other names: ATCC 25752, BCRC 14488, C. beijerinckii, CCUG 56442, CIP 104308, Clostridium rubrum, Clostridium sp. H18, DSM 791, LMG 5716, LMG:5716, NCIMB 9362, NCTC 13035

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AJG97025.1	AJH01598.1	LF65_00356	LF65_05070	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AJG97025.1	acdA_1	LF65_00356	LF65_02207	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
AJG97025.1	adhE_2	LF65_00356	LF65_01862	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.603
AJG97025.1	mmgB	LF65_00356	LF65_00359	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
AJH01598.1	AJG97025.1	LF65_05070	LF65_00356	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AJH01598.1	acdA_1	LF65_05070	LF65_02207	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
AJH01598.1	adhE_2	LF65_05070	LF65_01862	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.595
AJH01598.1	mmgB	LF65_05070	LF65_00359	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
acdA_1	AJG97025.1	LF65_02207	LF65_00356	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
acdA_1	AJH01598.1	LF65_02207	LF65_05070	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.902
acdA_1	adhE_2	LF65_02207	LF65_01862	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.603
acdA_1	mmgB	LF65_02207	LF65_00359	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958
adhE_2	AJG97025.1	LF65_01862	LF65_00356	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.603
adhE_2	AJH01598.1	LF65_01862	LF65_05070	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.595
adhE_2	acdA_1	LF65_01862	LF65_02207	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.603
adhE_2	mmgB	LF65_01862	LF65_00359	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.721
adhE_2	prs_2	LF65_01862	LF65_00104	Butanol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.	0.442
mmgB	AJG97025.1	LF65_00359	LF65_00356	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
mmgB	AJH01598.1	LF65_00359	LF65_05070	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.951
mmgB	acdA_1	LF65_00359	LF65_02207	3-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958

page 1 of 2

Server load: low (32%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About