STRINGSTRING
prs_2 prs_2 AJG96939.1 AJG96939.1 AJG96940.1 AJG96940.1 AJG96941.1 AJG96941.1 AJG96942.1 AJG96942.1 pgi pgi AJG97109.1 AJG97109.1 AJG97167.2 AJG97167.2 kdgA_1 kdgA_1 AJG97242.1 AJG97242.1 AJG97243.1 AJG97243.1 AJG97244.1 AJG97244.1 AJG97245.1 AJG97245.1 pfp pfp AJG97448.1 AJG97448.1 AJG97463.1 AJG97463.1 pgcA pgcA pfkA_1 pfkA_1 rpe_3 rpe_3 AJG98022.1 AJG98022.1 AJG98216.1 AJG98216.1 AJG98224.1 AJG98224.1 AJG98594.1 AJG98594.1 kdgK_2 kdgK_2 fba fba AJG98972.1 AJG98972.1 gntZ gntZ agaC_2 agaC_2 AJG99072.1 AJG99072.1 AJG99306.1 AJG99306.1 AJG99351.1 AJG99351.1 AJG99352.1 AJG99352.1 gapN gapN fbp fbp prs_1 prs_1 tal_5 tal_5 rpiA_2 rpiA_2 fda fda deoC deoC deoB deoB AJH00152.2 AJH00152.2 tal tal AJH00156.1 AJH00156.1 AJH00180.1 AJH00180.1 AJH00509.2 AJH00509.2 tal-2 tal-2 rbsK_1 rbsK_1 rbsK rbsK deoC-2 deoC-2 tal_4 tal_4 fbp-2 fbp-2 fbaA fbaA AJH01649.2 AJH01649.2 tal-3 tal-3 AJH01654.1 AJH01654.1 pfkA_2 pfkA_2 dxs_1 dxs_1 tktA_3 tktA_3 AJH02033.1 AJH02033.1 AJH02034.1 AJH02034.1 AMK50405.1 AMK50405.1 AMK50485.1 AMK50485.1 AMK50495.1 AMK50495.1 AMK50496.1 AMK50496.1 AMK50497.1 AMK50497.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prs_2Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (321 aa)
AJG96939.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AJG96940.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
AJG96941.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (223 aa)
AJG96942.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (449 aa)
AJG97109.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AJG97167.22-keto-3-deoxygluconate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
kdgA_12-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (208 aa)
AJG97242.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (272 aa)
AJG97243.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AJG97244.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (219 aa)
AJG97245.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (405 aa)
AJG97448.12-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (234 aa)
AJG97463.1Ribose-5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
pgcAPhosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (575 aa)
pfkA_16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (365 aa)
rpe_3Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (214 aa)
AJG98022.16-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
AJG98216.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AJG98224.1Ketose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AJG98594.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
kdgK_22-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AJG98972.1Ribose-phosphate pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
gntZ6-phosphogluconate dehydrogenase; Similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
agaC_2PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AJG99072.14-hydroxy-2-oxoglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
AJG99306.1Transaldolase; Similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AJG99351.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AJG99352.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
gapNGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (486 aa)
fbpClass 3; catalyzes the formation of fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
prs_1Phosphoribosylpyrophosphate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribose-phosphate pyrophosphokinase family. (363 aa)
tal_5Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
rpiA_2Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (233 aa)
fdaClass I fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I fructose-bisphosphate aldolase family. (295 aa)
deoC2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (216 aa)
deoBPhosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (396 aa)
AJH00152.2Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
talFructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
AJH00156.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AJH00180.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AJH00509.2Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
tal-2Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
rbsK_1Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (309 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (305 aa)
deoC-22-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (216 aa)
tal_4Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (215 aa)
fbp-2Class 3; catalyzes the formation of fructose 6-phosphate from fructose-1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (653 aa)
fbaAFructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
AJH01649.2Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (664 aa)
tal-3Fructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (218 aa)
AJH01654.1PTS N-acetylgalactosamine transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
pfkA_2ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (318 aa)
dxs_1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
tktA_3Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AJH02033.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AJH02034.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AMK50405.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
AMK50485.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa)
AMK50495.16-phospho 3-hexuloisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
AMK50496.13-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
AMK50497.12-dehydro-3-deoxygluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
Your Current Organism:
Clostridium beijerinckii
NCBI taxonomy Id: 1520
Other names: ATCC 25752, BCRC 14488, C. beijerinckii, CCUG 56442, CIP 104308, Clostridium rubrum, Clostridium sp. H18, DSM 791, LMG 5716, LMG:5716, NCIMB 9362, NCTC 13035
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